Volume 23 Issue 4
Apr.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(4): 576-579
DIAO Lei, WU Qiaoling, LIU Hong, LU Jian. Clinical analysis of small bowel polyps in patients with Peutz-Jeghers syndrome treated with double balloon enteroscopy[J]. Chinese Journal of General Practice, 2025, 23(4): 576-579. doi: 10.16766/j.cnki.issn.1674-4152.003954
Citation: DIAO Lei, WU Qiaoling, LIU Hong, LU Jian. Clinical analysis of small bowel polyps in patients with Peutz-Jeghers syndrome treated with double balloon enteroscopy[J]. Chinese Journal of General Practice, 2025, 23(4): 576-579. doi: 10.16766/j.cnki.issn.1674-4152.003954
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Clinical analysis of small bowel polyps in patients with Peutz-Jeghers syndrome treated with double balloon enteroscopy

doi: 10.16766/j.cnki.issn.1674-4152.003954

  • Department of Gastroenterology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 2022AH051137

  • Received Date: 2024-07-24
    Available Online: 2025-06-30
    Abstract
  •   Objective  To investigate the efficacy and safety of double balloon enteroscopy (DBE) in the treatment of small intestinal polyps in patients with Peutz-Jeghers syndrome (PJS).  Methods  A retrospective analysis was conducted on PJS patients who underwent DBE at the Department of Gastroenterology, the First Affiliated Hospital of Anhui Medical University, from June 2020 to November 2023. Clinical data of the patients were collected, and the success rate of small intestinal polyps resection as well as the incidence of intraoperative and postoperative complications were recorded.  Results  A total of 12 patients (7 males, 5 females) with a mean age of (29.94±13.29) years were included in our study. A total of 20 DBE procedures were performed (15 via the oral approach, and 5 via the anal approach). The mean intubation depth were (306.00±126.71) cm and (220.00±34.64) cm, respectively. Among the 12 patients, jejunum polyps were most common (100.0%), with gastric polyps observed in 2 cases (16.7%) and colonic polyps in 2 cases (16.7%). The number and size of small intestinal polyps varied, with the largest measuring approximately 5.0 cm in diameter and the smallest 0.3 cm. The success rate of polypectomy was 100.0%, and no serious complications were associated with endoscopic treatment. Five patients had two or more hospitalizations, with no significant difference in the maximum polyps diameter between the first and second hospitalizations [(1.70±0.98) cm vs. (2.67±0.58) cm, t=1.467, P=0.216], though a decreasing trend was observed. Follow-up results revealed that no cases of intussusception or intestinal obstruction caused by small bowel polyps after DBE.  Conclusion  DBE is an effective and safe method for the removal of small bowel polyps in patients with PJS.

     

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