Volume 23 Issue 7
Jul.  2025
Turn off MathJax
Article Contents
ZHU Qi, GAI Qiong, SHEN Fei, DING Zhuoying, PAN Yourang, LI Songtao. The effect of repetitive transcranial magnetic stimulation on emotion and cognitive level of depression patients with different theory of mind[J]. Chinese Journal of General Practice, 2025, 23(7): 1180-1182. doi: 10.16766/j.cnki.issn.1674-4152.004092
Citation: ZHU Qi, GAI Qiong, SHEN Fei, DING Zhuoying, PAN Yourang, LI Songtao. The effect of repetitive transcranial magnetic stimulation on emotion and cognitive level of depression patients with different theory of mind[J]. Chinese Journal of General Practice, 2025, 23(7): 1180-1182. doi: 10.16766/j.cnki.issn.1674-4152.004092

The effect of repetitive transcranial magnetic stimulation on emotion and cognitive level of depression patients with different theory of mind

doi: 10.16766/j.cnki.issn.1674-4152.004092
Funds:

 2024KY1735

 2022KY057

  • Received Date: 2024-11-28
    Available Online: 2025-10-25
  •   Objective  To explore the effect of repetitive transcranial magnetic stimulation (rTMS) on the improvement of emotional and cognitive levels in patients with depression with different theories of mind (TOM).  Methods  A total of 154 patients with depression admitted to Shaoxing Seventh People's Hospital from June 2023 to June 2024 were selected and divided into an intervention group (86 cases) and a control group (68 cases) according to the random number table method. The intervention group was further divided into a low TOM group (44 cases) and a high TOM group (42 cases) according to the median of the theory of mind picture-sequencing task (ToM-PST) score. The control group was treated with oral escitalopram oxalate, and the intervention group was treated with rTMS on this basis. The intervention period was 4 weeks. After the intervention, the total effective rate of patients in the low TOM group, the high TOM group, and the control group was compared, and the improvement of depression and cognitive level among the three groups was compared.  Results  The total effective rate of the high TOM group (76.19%, 32/42) was higher than that of the low TOM group (50.00%, 22/44) and the control group (38.24%, 26/68), and the difference was statistically significant (χ2=15.078, P=0.001). In terms of the improvement of depression level,'somatization/anxiety ','retardation ', and'sleep disorder'in the high TOM group were better than those in the control group. The'retardation'and'sleep disorder'in the low TOM group were better than those in the control group, and the difference was statistically significant (P < 0.05). In terms of cognitive improvement, the'attention'of the high TOM group was higher than that of the low TOM group and the control group; the'delayed recall'of the high TOM group and the low TOM group was better than that of the control group, and the difference was statistically significant (P < 0.05).  Conclusion  Repetitive transcranial magnetic stimulation has a certain auxiliary improvement effect on the emotion and cognition of patients with depression with different psychological theory abilities.

     

  • loading
  • [1]
    王丽英, 陈晶. 重度抑郁症患者肠道菌群代谢产物水平及其与炎症因子的相关性[J]. 中华全科医学, 2024, 22(9): 1563-1566. doi: 10.16766/j.cnki.issn.1674-4152.003683

    WANG L Y, CHEN J. Metabolite level of intestinal flora in patients with major depression and its correlation with inflammatory factors[J]. Chinese Journal of General Practice, 2024, 22(9): 1563-1566. doi: 10.16766/j.cnki.issn.1674-4152.003683
    [2]
    易峰, 汤莉, 李志佳. 非自杀性自我伤害者的社会认知特点及相关性研究[J]. 中国医师杂志, 2022, 24(8): 1246-1250.

    YI F, TANG L, LI Z J. A study on the social cognitive characteristics and correlation of non-suicidal self-harm victims[J]. Journal of Chinese Physician, 2022, 24(8): 1246-1250.
    [3]
    张淑婷, 沈悦娣, 刘兆宇. 重复经颅磁刺激对抑郁症病人认知功能影响的研究进展[J]. 护理研究, 2023, 37(21): 3886-3889.

    ZHANG S T, SHEN Y D, LIU Z Y. Research progress on effects of repetitive transcranial magnetic stimulation on cognitive function in patients with depression[J]. Chinese Nursing Research, 2023, 37(21): 3886-3889.
    [4]
    马丽景, 杨赞琦, 张佳, 等. 度洛西汀联合重复经颅磁刺激对重度抑郁症患者神经递质及认知功能的影响[J]. 中国康复, 2023, 38(5): 296-299.

    MA L J, YANG Z Q, ZHANG J, et al. Impacts of duloxetine combined with repetitive transcranial magnetic stimulation on neurotransmitters and cognitive function in patients with severe depression[J]. Chinese Journal of Rehabilitation, 2023, 38(5): 296-299.
    [5]
    CHEN Y X, LI X Z, WANG L B, et al. Effects of repetitive transcranial magnetic stimulation on cognitive function in patients with stress-related depression: a randomized double-blind fMRI and H-MRS study[J]. Front Neurol, 2022, 13: 844606. DOI: 10.3389/fneur.2022.844606.
    [6]
    陈海思, 高静芳, 王晓乐, 等. 重复经颅磁刺激联合舍曲林对首发青少年抑郁早期疗效及冷执行功能的影响[J]. 中华全科医学, 2022, 20(9): 1491-1494. doi: 10.16766/j.cnki.issn.1674-4152.002631

    CHEN H S, GAO J F, WANG X L, et al. Early effects and impacts on cold executive function of repetitive transcranial magnetic stimulation combined with sertraline in first-episode adolescent depression[J]. Chinese Journal of General Practice, 2022, 20(9): 1491-1494. doi: 10.16766/j.cnki.issn.1674-4152.002631
    [7]
    美国精神医学学会. 精神障碍诊断与统计手册[M]. 5版. 张道龙, 刘春宇, 张小梅, 等译. 北京: 北京大学出版社, 2015: 149-176.

    American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders[M]. 5th ed. Translated by ZHANG D L, LIU C Y, ZHANG X M, et al. Beijing: Peking University Press, 2015: 149-176.
    [8]
    张明园. 精神科评定手册[M]. 长沙: 湖南科学技术出版社, 1993: 16.

    ZHANG M Y. Psychiatric Assessment Handbook[M]. Changsha: Hunan Science and Technology Publishing House, 1993: 16.
    [9]
    HIERONYMUS F, LISINSKI A, NILSSON S, et al. Influence of baseline severity on the effects of SSRIs in depression: an item-based, patient-level post-hoc analysis[J]. Lancet Psychiatry, 2019, 6(9): 745-752. doi: 10.1016/S2215-0366(19)30216-0
    [10]
    陈红, 王立钢, 陈娇, 等. 问题解决疗法对首发老年抑郁症患者临床疗效、认知及社会功能的影响[J]. 中华行为医学与脑科学杂志, 2024, 33(1): 45-50.

    CHEN H, WANG L G, CHEN J, et al. Effect of problem-solving therapy on clinical efficacy, cognitive and social function in senile patients with first episode depression[J]. Chinese Journal of Behavioral Medicine and Brain Science, 2024, 33(1): 45-50.
    [11]
    胡淑文, 钟慧, 莫大明, 等. 青少年抑郁障碍患者心理理论能力与自杀未遂的相关性研究[J]. 中华行为医学与脑科学杂志, 2022, 31(3): 241-247.

    HU S W, ZHONG H, MO D M, et al. Correlation between theory of mind and attempted suicide in adolescents with depressive disorder[J]. Chinese Journal of Behavioral Medicine and Brain Science, 2022, 31(3): 241-247.
    [12]
    刘梦婉, 卢虹冰, 王化宁, 等. 基于磁共振成像技术的孤独症患者脑连接异常的研究进展[J]. 中华精神科杂志, 2020, 53(4): 351-355.

    LIU M W, LU H B, WANG H N, et al. Brain connectivity abnormity analysis in autism spectrum disorder based on magnetic resonance imaging[J]. Chinese Journal of Psychiatry, 2020, 53(4): 351-355.
    [13]
    黄方珺, 刘铁榜. 心理理论能力对首次住院青少年抑郁障碍患者非自杀性自伤行为的影响[J]. 中华行为医学与脑科学杂志, 2022, 31(11): 990-995.

    HUANG F J, LIU T B. Effect of theory of mind on non-suicidal self-injury behavior in adolescent patients with depressive disorder for the first hospitalization[J]. Chinese Journal of Behavioral Medicine and Brain Science, 2022, 31(11): 990-995.
    [14]
    GIANNAKOU M, KOSMIDIS M H, NAZLIDOU E I, et al. Understanding of faux pas in patients with schizophrenia[J]. Psychiatriki, 2019, 30(1): 17-23. doi: 10.22365/jpsych.2019.301.17
    [15]
    彭琪, 钟笑梅. 非侵入式脑刺激技术治疗老年抑郁症的研究进展[J]. 中华精神科杂志, 2024, 57(10): 685-691.

    PENG Q, ZHONG X M. Research progress on non-invasive brain stimulation techniques for treating geriatric depression[J]. Chinese Journal of Psychiatry, 2024, 57(10): 685-691.
    [16]
    李琪, 张红, 杨文东, 等. 重复经颅磁刺激治疗创伤后抑郁症的临床研究进展[J]. 中华神经医学杂志, 2024, 23(3): 304-309.

    LI Q, ZHANG H, YANG W D, et al. Recent advance in clinical application of transcranial magnetic stimulation in post-traumatic depression[J]. Chinese Journal of Neuromedicine, 2024, 23(3): 304-309.
    [17]
    关慕桢, 王中恒, 武文珺, 等. 重复经颅磁刺激治疗对抑郁症患者脑自发活动的影响[J]. 中华精神科杂志, 2022, 55(5): 383-392.

    GUAN M Z, WANG Z H, WU W J, et al. Altered brain spontaneous activity by repetitive transcranial magnetic stimulation treatment for major depressive disorder[J]. Chinese Journal of Psychiatry, 2022, 55(5): 383-392.
    [18]
    司飞飞, 刘璐, 李海梅, 等. 注意缺陷多动障碍共患对立违抗障碍儿童大脑皮质形态学特点[J]. 中国心理卫生杂志, 2024, 38(2): 97-103.

    SI F F, LIU L, LI H M, et al. Characteristics of brain cortical morphology in children with attention deficit hyperactivity disorder co-occurred with oppositional defiant disorder[J]. Chinese Mental Health Journal, 2024, 38(2): 97-103.
    [19]
    刘同辉, 李朋, 张华文, 等. 基于后扣带回功能连接研究乳腺癌患者化疗相关认知障碍的脑功能异常[J]. 医学影像学杂志, 2024, 34(5): 5-8, 14.

    LIU T H, LI P, ZHANG H W, et al. Study on brain dysfunction of chemotherapy related cognitive impairment in breast cancer patients based on posterior cingulate cortex functional connectivity[J]. Journal of Medical Imaging, 2024, 34(5): 5-8, 14.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Article Metrics

    Article views (11) PDF downloads(0) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return