Volume 23 Issue 7
Jul.  2025
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(7): 1192-1195
WANG Xing, LU Fang, SHI Yan, LI Yang, XIE Changhao. Evaluation of ultrafast pulse wave technique in subclinical atherosclerosis in SLE and its clinical correlates[J]. Chinese Journal of General Practice, 2025, 23(7): 1192-1195. doi: 10.16766/j.cnki.issn.1674-4152.004095
Citation: WANG Xing, LU Fang, SHI Yan, LI Yang, XIE Changhao. Evaluation of ultrafast pulse wave technique in subclinical atherosclerosis in SLE and its clinical correlates[J]. Chinese Journal of General Practice, 2025, 23(7): 1192-1195. doi: 10.16766/j.cnki.issn.1674-4152.004095
shu

Evaluation of ultrafast pulse wave technique in subclinical atherosclerosis in SLE and its clinical correlates

doi: 10.16766/j.cnki.issn.1674-4152.004095
  • 1.

    Graduate School of Bengbu Medical University, Bengbu, Anhui 233000, China

Funds:

 AHWJ2023A20372

 2108085MH258

  • Received Date: 2024-08-20
    Available Online: 2025-10-25
    Abstract
  •   Objective  To make an assessment of vascular elasticity in patients with systemic lupus erythematosus (SLE) at varying levels of disease activity using ultrafast pulse wave technique, and to investigate associated clinical risk factors.  Methods  A total of 116 SLE patients admitted to the First Affiliated Hospital of Bengbu Medical University from October 2020 to April 2024 were selected. Patients were divided into a mild activity group (n=57) and a moderate-to-severe activity group (n=59) according to SLE disease activity index 2000. Additionally, 45 healthy adults were included as the control group. Carotid intima-media thickness (IMT), pulse wave velocity at the beginning of systole (PWV-BS), and pulse wave velocity at the end of systole (PWV-ES) were measured in each group. Clinical data of each group were recorded and analyzed. Carotid artery parameters and clinical data of the three groups were compared to analyze the correlation between PWV parameters and various indicators.  Results  Both PWV-BS and PWV-ES showed significant differences among the three groups, following the pattern: moderate-to-severe activity group > light activity group > control group (P < 0.05). PWV-BS was positively correlated with common carotid artery IMT (r=0.315, P < 0.001), systolic blood pressure (r=0.190, P=0.041), and diastolic blood pressure (r=0.191, P=0.040). PWV-ES was positively correlated with carotid bifurcation IMT (r=0.274, P=0.003), common carotid artery IMT (r=0.361, P < 0.001), and diastolic blood pressure (r=0.252, P=0.006).  Conclusion  The reduction in carotid artery elasticity in SLE patients occurs significantly earlier compared to healthy individuals. Ultrafast pulse wave is valuable, time-independent, and objective tool for quantitative assessing early vascular changes in patients with SLE, thus facilitating the early detection and clinical management of atherosclerosis.

     

    • FullText(HTML)
  • loading
    • References(18)
  • [1]
    LAZAR S, KAHLENBERG J M. Systemic lupus erythematosus: new diagnostic and therapeutic approaches[J]. Annu Rev Med, 2023, 74(1): 339-352. doi: 10.1146/annurev-med-043021-032611
    [2]
    FANOURIAKIS A, TZIOLOS N, BERTSIAS G, et al. Update on the diagnosis and management of systemic lupus erythematosus[J]. Ann Rheum Dis, 2021, 80(1): 14-25. doi: 10.1136/annrheumdis-2020-218272
    [3]
    KATAYAMA Y, YANAI R, ITAYA T, et al. Risk factors for cardiovascular diseases in patients with systemic lupus erythematosus: an umbrella review[J]. Clin Rheumatol, 2023, 42(11): 2931-2941. doi: 10.1007/s10067-023-06608-6
    [4]
    OLIVEIRA C B, KAPLAN M J. Cardiovascular disease risk and pathogenesis in systemic lupus erythematosus[J]. Semin Immunopathol, 2022, 44(3): 309-324. doi: 10.1007/s00281-022-00922-y
    [5]
    MINANO S, GONZALEZ-CORREA C, MOLEON J, et al. Metabolic modulators in cardiovascular complications of systemic lupus erythematosus[J]. Biomedicines, 2023, 11(12): 3142. DOI: 10.3390/biomedicines11123142.
    [6]
    WU X L, ZHANG S M, JIN Y Z, et al. Sex-related differences in sitagliptin treatment in type 2 diabetes: results from the PROLOGUE trial[J]. Med Sci Monit, 2022, 28: e938030. DOI: 10.12659/MSM.938030.
    [7]
    刁玉红, 刘志兴, 彭娟, 等. 超声极速成像技术评价烟雾病患者颈动脉血管弹性的临床应用价值[J]. 中国超声医学杂志, 2023, 39(1): 99-102.

    DIAO Y H, LIU Z X, PENG J, et al. Evaluation of carotid artery elasticity by hypervelocity ultrasound in patients with moyamoya disease[J]. Chinese Journal of Ultrasound in Medicine, 2023, 39(1): 99-102.
    [8]
    DZIEDZIC-OLEKSY H, MAZUREK A, BUGALA K, et al. Arterial stiffness and atherosclerosis in systemic lupus erythematosus patients[J]. Reumatologia, 2022, 60(3): 165-172. doi: 10.5114/reum.2022.117836
    [9]
    HONCHBERG M C. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus[J]. Arthritis Rheum, 1997, 40(9): 1725. DOI: 10.1002/art.1780400928.
    [10]
    乔敏, 陆萍萍, 沈德娟. 颈动脉斑块报告和数据系统联合临床特征对脑卒中的预测价值[J]. 中国超声医学杂志, 2024, 40(9): 961-963.

    QIAO M, LU P P, SHEN D J. The predictive value of plaque reporting and data system combined with clinical features for stroke[J]. Chinese Journal of Ultrasound in Medicine, 2024, 40(9): 961-963.
    [11]
    CHITPET P, CHAIAMNUAY S, NARONGROEKNAWIN P. The effect of systemic lupus erythematosus (SLE) disease activity score and SLE disease activity index 2000-based remission states in patients with SLE on damage accrual[J]. Int J Rheum Dis, 2023, 26(12): 2509-2516. doi: 10.1111/1756-185X.14949
    [12]
    NELSON M C, CHANDRAKASAN S, PONDER L, et al. Clinical determinants of childhood onset systemic lupus erythematosus among early and peri-adolescent age groups[J]. Children, 2022, 9(12): 1865. DOI: 10.3390/children9121865.
    [13]
    杨雅淇, 温军业, 高丽, 等. 极速脉搏波技术对SLE患者颈动脉弹性定量评价的初步研究[J]. 影像科学与光化学, 2021, 39(6): 823-826.

    YANG Y Q, WEN J Y, GAO L, et al. Preliminary study on the value of ultrafast pulse wave velocity in quantitative evaluation of carotid artery elasticity in patients with systemic lupus erythematosus[J]. Imaging Science and Photochemistry, 2021, 39(6): 823-826.
    [14]
    安欣, 李宜函, 葛丽丽, 等. 极速脉搏波技术评价原发性干燥综合征患者颈动脉弹性[J]. 中国医学影像学杂志, 2022, 30(12): 1218-1223.

    AN X, LI Y H, GE L L, et al. Carotid artery elasticity in patients with primary Sjogren's syndrome evaluated by ultrafast pulse wave velocity[J]. Chinese Journal of Medical Imaging, 2022, 30(12): 1218-1223.
    [15]
    孔淑君, 石彦, 宁艳, 等. 极速脉搏波技术在系统性红斑狼疮患者颈动脉弹性功能检测中的应用价值[J]. 中华全科医学, 2022, 20(8): 1380-1383. doi: 10.16766/j.cnki.issn.1674-4152.002602

    KONG S J, SHI Y, NING Y, et al. Application value of ultrafast pulse wave velocity in carotid artery elastic function detection in patients with systemic lupus erythematosus[J]. Chinese Journal of General Practice, 2022, 20(8): 1380-1383. doi: 10.16766/j.cnki.issn.1674-4152.002602
    [16]
    LAMPSAS S, XENOU M, OIKONOMOU E, et al. Lipoprotein(a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment[J]. Molecules, 2023, 28(3): 969. DOI: 10.3390/molecules28030969.
    [17]
    陈群, 严远飞, 陈数, 等. 系统性红斑狼疮合并心脏损害的相关危险因素分析[J]. 实用临床医药杂志, 2022, 26(1): 109-115.

    CHEN Q, YAN Y F, CHEN S, et al. Analysis of risk factors of systemic lupus erythematosus complicated with cardiac damage[J]. Journal of Clinical Medicine in Practice, 2022, 26(1): 109-115.
    [18]
    MA X H, ZHU Z Q, WANG Y P, et al. Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging[J]. Ultrasonography, 2023, 42(1): 89-99. doi: 10.14366/usg.22039
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(5)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (6) PDF downloads(0) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return