Volume 23 Issue 9
Sep.  2025
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BAO Lichao, HE Ying. Application of precision nutrition intervention based on patient subjective holistic assessment in nursing care of patients with colorectal cancer[J]. Chinese Journal of General Practice, 2025, 23(9): 1614-1617. doi: 10.16766/j.cnki.issn.1674-4152.004189
Citation: BAO Lichao, HE Ying. Application of precision nutrition intervention based on patient subjective holistic assessment in nursing care of patients with colorectal cancer[J]. Chinese Journal of General Practice, 2025, 23(9): 1614-1617. doi: 10.16766/j.cnki.issn.1674-4152.004189

Application of precision nutrition intervention based on patient subjective holistic assessment in nursing care of patients with colorectal cancer

doi: 10.16766/j.cnki.issn.1674-4152.004189
Funds:

 LTGY24H160038

  • Received Date: 2024-12-26
    Available Online: 2025-11-17
  •   Objective  To construct a precision nutrition intervention program for colorectal cancer based on patient-generated subjective global assessment (PG-SGA), and to provide a reference for the nutritional management of similar patients.  Methods  A total of 101 patients with colorectal cancer who were treated in Huzhou First People ' s Hospital from March 2022 to March 2024 were selected and divided into a control group (n=50) and an observation group (n=51) by random number table method. The control group received conventional nutrition intervention, while the observation group received PG-SGA-based precision nutrition intervention. Nutritional status, immune function, incidence of gastrointestinal adverse reactions during chemotherapy, and the score of the European organization research and therapeutic tissue quality of life scale (EORTCQLQ-C30) were compared between the two groups.  Results  There was no significant difference in BMI and upper arm circumference between the observation group and the control group after intervention (P>0.05). The levels of total protein [(63.44±7.22) g/L vs. (52.09±6.73) g/L], albumin [(35.77±6.73) g/L vs. (30.12±5.25) g/L] and hemoglobin [(110.98±11.23) g/L vs. (95.45±5.67) g/L] were higher than those of control group (P < 0.05); CD3+ [(71.22±8.94) % vs. (60.09±7.85) %], CD4+ [(47.80±6.32) % vs. (39.09±5.66) %] and CD4+/CD8+(1.70±0.45 vs. 1.49±0.37) were higher than those in the control group (P < 0.05). The total incidence of gastrointestinal adverse reactions was lower than that of the control group (P < 0.05). The scores of EORTCQLQ-C30 were higher than those of the control group (P < 0.05).  Conclusion  Precise nutritional intervention based on PG-SGA can improve the nutritional status of colorectal cancer patients, improve immune function, reduce the adverse reactions of chemotherapy, and improve the quality of life.

     

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