Volume 29 Issue 10
Oct.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(10): 1694-1696
HUANG Xiuqin, YAO Haixin, ZHANG Yang, XU Lijuan, ZHUGE Weiwei, HU Tingting. The correlation between geriatric nutritional risk index and long-term prognosis of patients with ulcerative colitis[J]. Chinese Journal of General Practice, 2025, 23(10): 1694-1696. doi: 10.16766/j.cnki.issn.1674-4152.004207
Citation: HUANG Xiuqin, YAO Haixin, ZHANG Yang, XU Lijuan, ZHUGE Weiwei, HU Tingting. The correlation between geriatric nutritional risk index and long-term prognosis of patients with ulcerative colitis[J]. Chinese Journal of General Practice, 2025, 23(10): 1694-1696. doi: 10.16766/j.cnki.issn.1674-4152.004207
shu

The correlation between geriatric nutritional risk index and long-term prognosis of patients with ulcerative colitis

doi: 10.16766/j.cnki.issn.1674-4152.004207

  • Nursing Department, Ward 122 Department of Gastroenterology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funds:

 2023RC206

  • Received Date: 2025-01-26
    Abstract
  •   Objective  To retrospectively analyze risk factors for poor long-term prognosis in patients with ulcerative colitis (UC) and to explore the correlation between the Geriatric nutritional risk index (GNRI) and the long-term prognosis of patients with UC.  Methods  A total of 136 patients with UC who were treated at the First Affiliated Hospital of Wenzhou Medical University from January 1, 2020 to December 31, 2021 were enrolled. Colonoscopy was reexamined after 3 years of treatment. According to the reexamination results, the patients were divided into the good prognosis group (n=92) and the poor prognosis group (n=44). The clinical data of the two groups of patients were compared. Spearman correlation analysis was used to analyze the correlations between GNRI and Mayo score, presence of extraintestinal manifestations, and lesion involvement of the entire colon, and the independent risk factors influencing the poor long-term prognosis of UC patients were analyzed through multivariate logistic regression. The clinical value of GNRI in predicting poor long-term prognosis was analyzed by using the receiver operating characteristic (ROC) curve.  Results  The GNRI in the good prognosis group was higher than that in the poor prognosis group (104.74±10.49 vs. 94.24±11.20). The Mayo score, the proportion of patients with extraintestinal manifestations, and the proportion of patients with lesions involving the entire colon were all lower than those in the poor prognosis group [(6.74±2.18) points vs. (8.61±2.44) points, 9.78% (9/92) vs. 27.27% (12/44), 11.96% (11/92) vs. 31.82% (14/44), P < 0.05]. Multivariate logistic regression analysis showed that decreased GNRI, elevated Mayo score, and total colonic lesions were independent risk factors for poor long-term prognosis in UC patients (P < 0.05). ROC curve analysis showed that the area under the curve of GNRI for predicting poor long-term prognosis in UC patients was 0.734 (95% CI: 0.650-0.818, P < 0.001).  Conclusion  The GNRI is an independent risk factor for the poor long-term prognosis of patients with UC and can predict the poor long-term prognosis of patients with UC.

     

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