Volume 29 Issue 10
Oct.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(10): 1706-1708
ZENG Defei, LI Yanan, LIU Xiaoyu. Analysis of influencing factors of mild cognitive impairment in middle-aged and elderly patients with chronic atrial fibrillation[J]. Chinese Journal of General Practice, 2025, 23(10): 1706-1708. doi: 10.16766/j.cnki.issn.1674-4152.004210
Citation: ZENG Defei, LI Yanan, LIU Xiaoyu. Analysis of influencing factors of mild cognitive impairment in middle-aged and elderly patients with chronic atrial fibrillation[J]. Chinese Journal of General Practice, 2025, 23(10): 1706-1708. doi: 10.16766/j.cnki.issn.1674-4152.004210
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Analysis of influencing factors of mild cognitive impairment in middle-aged and elderly patients with chronic atrial fibrillation

doi: 10.16766/j.cnki.issn.1674-4152.004210

  • Department of General Practice, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China

Funds:

 SYJS2020026

  • Received Date: 2024-06-25
    Abstract
  •   Objective  To investigate the influencing factors of mild cognitive function impairment in middle-aged and elderly patients with chronic atrial fibrillation (AF), as to improve the cognitive function of chronic AF patients.  Methods  A total of 102 patients with chronic atrial fibrillation (AF group) and 102 patients with sinus rhythm (SR group) who visited the Department of General Medicine at the First Affiliated Hospital of Zhengzhou University from February 2023 to February 2024 were included. The Montreal cognitive assessment scale (MoCA) was used to assess the patients ' cognitive function. According to the MoCA score, the patients with chronic AF were divided into a cognitive impairment group (n=53) and a non-cognitive impairment group (n=49) for univariate and multivariate analyses.  Results  The MoCA scores of the chronic AF group and the SR group were (23.94±3.28) points and (27.17±2.51) points, respectively, and the difference was statistically significant (P < 0.05). Compared with SR group, CHA2DS2-VASc score and Pittsburgh sleep quality index (PSQI) score were higher in AF group, the proportion of AF combined with heart and the proportion of using anticoagulant and beta blockers were higher than those of SR group, and the differences were statistically significant (P < 0.05). Univariate and multivariate logistic regression analysis revealed that age and CHA2DS2-VASc score were the influencing factors of mild cognitive impairment in patients with chronic AF (P < 0.05).  Conclusion  The cognitive function of patients with chronic AF is significantly lower than that of SR group, and the most significant decrease is in visuospatial and executive function, memory and delayed recall, attention and calculation, language, and orientation. The age and CHA2DS2-VASc score are the influencing of mild cognitive impairment in chronic AF patients.

     

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