Volume 29 Issue 10
Oct.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(10): 1761-1763
WANG Shiqiang, LIU Wenbing, ZHANG Yuna, YUAN Feng, JIN Xinlai. Effects of transcranial direct current stimulation on therapeutic effect and cognitive function in patients with depression[J]. Chinese Journal of General Practice, 2025, 23(10): 1761-1763. doi: 10.16766/j.cnki.issn.1674-4152.004223
Citation: WANG Shiqiang, LIU Wenbing, ZHANG Yuna, YUAN Feng, JIN Xinlai. Effects of transcranial direct current stimulation on therapeutic effect and cognitive function in patients with depression[J]. Chinese Journal of General Practice, 2025, 23(10): 1761-1763. doi: 10.16766/j.cnki.issn.1674-4152.004223
shu

Effects of transcranial direct current stimulation on therapeutic effect and cognitive function in patients with depression

doi: 10.16766/j.cnki.issn.1674-4152.004223
  • 1.

    Department of Respiratory Medicine, Hangzhou Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang 310007, China

Funds:

 2024KY1391

  • Received Date: 2025-03-04
    Abstract
  •   Objective  To investigate the effect of a multidisciplinary pulmonary rehabilitation program based on the timing theory on mechanically ventilated patients with severe pneumonia. The ultimate goal is to provide a basis for the pulmonary rehabilitation treatment of patients with severe pneumonia undergoing mechanical ventilation.  Methods  A total of 60 patients diagnosed with severe pneumonia were selected for this study. The patients were admitted to the Respiratory Intensive Care Unit of Hangzhou Hospital of Traditional Chinese Medicine and the Third Affiliated Hospital of Zhejiang Chinese Medical University from March to December 2024. The patients were divided into two groups: the control group and the treatment group. The random number table method was used to assign patients to each group. Each group contained 30 patients. The control group received routine nursing. The treatment group received a multidisciplinary pulmonary rehabilitation program based on timing theory. The efficacy indexes—which include the length of ICU stay, duration of mechanical ventilation, and acute physiology and chronic health (APACHE-Ⅱ) score, as well as the blood gas indexes [arterial partial pressure of carbon dioxide (PaCO2), arterial partial pressure of oxygen (PaO2), blood oxygen saturation (SaO2), oxygenation index], quality of life and adverse events were compared between the two groups.  Results  Following the intervention, the treatment group exhibited a significant reduction in the duration of ICU stay [(7.48±1.37) d vs. (9.65±1.45) d], the duration of mechanical ventilation [(6.26±1.08) d vs. (8.41±1.61) d], and the APACHE-Ⅱ score [(9.14±1.75) points vs. (12.71±2.54) scores] were lower than those in the control group (P < 0.001). The PaCO2 in the treatment group [(29.35±4.53) mmHg vs. (37.18±4.92) mmHg, 1 mmHg=0.133 kPa], PaO2 [(84.69±7.45) mmHg vs. (77.84±7.19) mmHg], oxygenation index [(405.94±40.58) mmHg vs. (319.02±34.72) mmHg] were better than those in the control group (P < 0.05). The scores of quality of life in the treatment group were higher than those in the control group (P < 0.05). No obvious adverse events occurred in the two groups during treatment.  Conclusion  The multidisciplinary pulmonary rehabilitation program based on the timing theory is safe and effective, offering a new strategy for pulmonary rehabilitation in mechanically ventilated patients with severe pneumonia.

     

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