Analysis of diagnostic efficacy of fine-needle aspiration for ultrasonic parameters of thyroid nodules

Objective To investigate diagnostic effectiveness of ultrasound-guided fine-needle aspiration(US-FNA) for the sonographic features of thyroid nodules like size and calcification. Methods A retrospective analysis of the clinical patients of 614 thyroid nodules from 2012 to 2014.According to the maximal diameter of thyroid nodules,the nodules were divided into group A(≤ 5 mm),B(5-10 mm),and C(>10 mm),and according to the calcification,the nodules were divided into group N(no calcification),group Mi(Microcalcification) and group Ma(Macrocalcification).By the Bethesda System,>grade IV was the malignant cytologic criteria for diagnosis of thyroid nodules.At the same receiver operating characteristic curve was to evaluate the diagnosis of size and calcification between groups. Results ①In group A,the sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of US-FNA were 92.1%,96.6%,94.0%,97.2%,and 90.3%.In group B,they were 91.1%,95.3%,93.0%,96.3%,and 89.1%.In group C,they were 93.6%,96.2%,95.1%,94.8% and 95.2%,respectively.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of the three groups showed no significant difference(P>0.05).In group N,they were 93.6%,96.4%,93.6%,96.3% and 90.9%.In group Mi,they were 89.5%,88.9%,93.0%,95.1% and 89.7%,and in group Ma,they were 96%,97.1%,96.8%,96.6% and 97.1%,respectively.The three groups also show no significant difference(P>0.05).②AUC of group A,B,and C were 0.94,0.93,and 0.95,while group N,Mi,and Ma were 0.94,0.93,and 0.97. Conclusion US-FNA is not limited to the size,calcification of thyroid nodules,but have high diagnostic value.