Effect of epidural anesthesia for cesarean section on hemodynamics of patients with severe pre-eclampsia

Objective To investigate the effect of epidural anesthesia for cesarean section on hemodynamics of patients with severe pre-eclampsia. Methods Selected 90 cases of severe preeclampsia as the experimental group,90 cases of healthy pregnant women as the control group from April,2013 to March,2014 in Ninghai County MCH.The pregnant women in two groups were cesarean section underwent epidural anesthesia.The changes of blood pressure and heart rate before and after anesthesia,birth weight and Apgar score and the situation hypotension were observed in two groups pregnant women. Results The infusion volume(1 067±315)ml,the amount of lidocaine(4.5±2.7)ml and ephedrine(6.5±2.9)mg in anesthesia of experimental group pregnant women were lower than that of the control group(1 358.0±322.0)ml,(7.3±3.1)ml,(14.1±6.7)mg (P<0.05).The birth weight in the experimental group(975±675)g was lower than that of the control group(3 214±602)g(P<0.05),the newborns 1 min Apgar score ≤ 7 proportion in the experimental group(28.9%) was higher than that of the control group(12.2%,P<0.05),the newborns 5 min Apgar score ≤ 7 proportion in the experimental group was higher than that of the control group,but the difference was not statistically significant(P>0.05).Systolic blood pressure and diastolic blood pressure:the blood pressure before anesthesia,the minimum blood pressure after anesthesia,blood pressure before anesthesia-minimum blood pressure after anesthesia of experimental group pregnant women were significantly higher that of the control group(P<0.05).The heart rate before anesthesia,the minimum heart rate after anesthesia,heart rate before anesthesia-minimum heart rate after anesthesia of experimental group pregnant women[(98.2±15.7,82.9±16.3,16.7±11.6)times/min] were significantly higher than those of the control group[(82.6±11.5,76.1±13.8,6.5±10.4)times/min,P<0.05].The incidence of hypotension in the experimental group(68.9%) was significantly higher than that of the control group(35.6%,P<0.05). Conclusion The rate of hypotension in severe preeclampsia patients with cesarean delivery under epidural anesthesia is high,should pay attention to the prevention of hypotension in cesarean delivery.