Compare bronchoalveolar lavage via nasal or tracheal cannula in pathogenic diagnosis and drug resistance rate monitoring of pulmonary infection

Objective To investigate the value of bronchoalveolar lavage (BAL) via nasal or tracheal cannula in pathogenic diagnosis and drug resistance rate monitoring of pulmonary infection (PI). Methods We conducted a retrospective analysis of pathogenic detection and drug resistance rate by bronchoalveolar lavage via nasal or tracheal cannula in patients with PI from 2013 to 2015;the data were analyzed by SPSS 19.0 and WHONET 5 software. Results Total 1 332 patients with pulmonary infection underwent bronchoalveolar lavage by fiberoptic bronchoscopy in 3 years,207 cases via nasal (A group) and 1 125 cases via tracheal cannula (B group),and 84.5% of specimens were in the Intensive Care Unit (ICU) and neurosurgery ward.The qualification rates were similar in the 2 groups,which were 99.0% and 99.6%,respectively (P>0.05);the pathogenic detecting rate of bronchoalveolar lavage fluid (BALF) were also similar between the 2 groups,with an 85.5% and 86.9%,respectively (P>0.05).The pathogenic distributions were similar except Acinetobacter spp,however,drug resistant rates to most antibiotics were different between the 2 groups (P>0.05). Conclusions Both of transnasal or transtracheal cannula bronchoalveolar lavages are a high value approach in the pathogenic diagnosis and drug resistance monitor of pulmonary infection.