2型糖尿病患者营养风险筛查及其影响因素分析

李靖; 周玉森; 郝树立; 武炜; 马国旗

doi:10.16766/j.cnki.issn.1674-4152.003334

2型糖尿病患者营养风险筛查及其影响因素分析

doi: 10.16766/j.cnki.issn.1674-4152.003334

李靖¹,
周玉森^2, ,,
郝树立³,
武炜²,
马国旗⁴

1.
亳州市人民医院膳食营养科，安徽亳州 236804
2.
亳州市人民医院内分泌科
3.
亳州市人民医院口腔科
4.
亳州市人民医院临床营养科

基金项目:

安徽省卫生健康科研项目 AHWJ2022b117

详细信息

通讯作者:
周玉森，E-mail：zhouyusen9180@163.com

中图分类号: R587.1 R459.3
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- 文章访问数: 283
- HTML全文浏览量: 75
- PDF下载量: 30
- 被引次数: 0
出版历程
- 收稿日期: 2023-09-06
- 网络出版日期: 2024-03-09

Nutritional risk screening and influencing factors in patients with type 2 diabetes

LI Jing¹,
ZHOU Yusen^{2
, ,},
HAO Shuli³,
WU Wei²,
MA Guoqi⁴

1.
Dietary Nutrition Department of the People's Hospital of Bozhou, Bozhou, Anhui 236804, China

摘要

摘要: 目的基于营养风险筛查2002(NRS2002)系统分析2型糖尿病患者的营养状况，研究患者营养风险的主要影响因素。方法选取2022年10月10日—2023年5月9日亳州市人民医院收治的糖尿病住院患者196例，根据有无营养风险分为有营养风险组(35例)和无营养风险组(161例)。分析患者的性别和相关生化指标(血红蛋白、糖化血红蛋白、白蛋白、总胆固醇、甘油三酯、尿素氮和肌酐)在有、无营养风险患者中的差异，采用多元logistic回归分析研究营养风险的独立影响因素。结果不同性别患者营养风险的发生差异无统计学意义(P>0.05)。相关临床生化检测结果显示，有营养风险的T2DM患者血清血红蛋白、白蛋白、尿素氮、肌酐分别为(122.29±10.07)g/L、(40.98±3.61)g/L、(6.97±0.16)mmol/L、(86.91±5.96)mmol/L，与无营养风险患者比较差异均有统计学意义[(128.15±9.96)g/L、(43.38±4.34)g/L、(5.81±0.92)mmol/L、(79.75±8.56)mmol/L，P＜0.05]；有、无营养风险患者糖化血红蛋白、总胆固醇及血清甘油三酯比较差异均无统计学意义(P＞0.05)。多元logistic回归分析显示，血红蛋白、白蛋白和肌酐是T2DM患者发生营养风险的影响因素。结论应用NRS2002评估T2DM患者营养状况，血红蛋白、白蛋白和肌酐水平是T2DM患者发生营养风险的影响因素。
- 营养风险筛查2002 /
- 2型糖尿病 /
- 营养风险 /
- 糖化血红蛋白 /
- 白蛋白
Abstract: Objective To systematically analyze the nutritional status of type 2 diabetes (T2DM) patients based on nutrition risk screening (NRS2002), and screen the main impact indicators of nutritional risk. Methods A total of 196 T2DM patients were obtained from the People's Hospital of Bozhou between October 10, 2022 and May 9, 2023. The patients were divided into nutritional risk group (35 cases) and non-nutritional risk group (161 cases) based on the presence or absence of nutritional risk. Statistical analysis was used to investigate the differences in gender and related biochemical indicators (hemoglobin, glycated hemoglobin, albumin, total cholesterol, triglycerides, urea nitrogen, creatinine) between patients with and without nutritional risk. The independent influencing factors of nutritional risk were analyzed using multiple logistic regression analysis. Results There was no significant difference in the occurrence of nutritional risks between different genders (P>0.05). The relevant clinical biochemical test results showed that T2DM patients with nutritional risk had significant differences in serum hemoglobin [(122.29±10.07) g/L], albumin [(40.98±3.61) g/L], urea nitrogen [(6.97±0.16) mmol/L], and creatinine [(86.91±5.96) mmol/L] levels compared to non-nutritional risk patients [(128.15±9.96) g/L, (43.38±4.34) g/L, (5.81±0.92) mmol/L, (79.75±8.56) mmol/L, respectively, P < 0.05]. There was no significant difference in the statistics of glycated hemoglobin, total cholesterol, and serum triglycerides between patients with and without nutritional risk (P>0.05). Multiple logistic regression analysis was used to analyze hemoglobin, albumin, urea nitrogen, and creatinine. The results showed that hemoglobin, albumin, and creatinine were related risk factors for nutritional risk in T2DM patients. Conclusion NRS2002 is applied to assess the nutritional status of patients with T2DM, and haemoglobin, albumin and creatinine levels are influential factors in the occurrence of nutritional risk in patients with T2DM.
- Nutrition risk screening 2002 /
- Type 2 diabetes /
- Nutritional risk /
- Glycated hemoglobin /
- Albumin

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表 1 不同性别T2DM患者营养风险比较[例(%)]

Table 1. Comparison of nutritional risks between T2DM patients in different genders[cases (%)]

性别	例数	有营养风险	无营养风险
男性	105	19(18.1)	86(81.9)
女性	91	16(17.6)	75(82.4)
注：χ²=0.009，P=0.926。

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表 2 有无营养风险T2DM患者生化指标比较(x±s)

Table 2. Comparison of biochemical indicators in patients with and without nutritional risk(x±s)

组别	例数	血红蛋白(g/L)	白蛋白(g/L)	前白蛋白(mg/L)	糖化血红蛋白(%)	尿素氮(mmol/L)	肌酐(mmol/L)	总胆固醇(mmol/L)	甘油三酯(mmol/L)
有营养风险	35	122.29±10.07	40.98±3.61	168.58±9.53	11.89±1.37	6.97±0.16	86.91±5.96	5.43±0.66	1.57±0.40
无营养风险	161	128.15±9.96	43.38±4.34	181.20±48.88	10.89±6.15	5.81±0.92	79.75±8.56	5.26±0.48	1.49±0.26
t值		3.147	3.062	1.528	0.950	7.482	4.699	1.729	1.432
P值		0.002	0.003	0.131	0.343	< 0.001	< 0.001	0.085	0.154

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表 3 T2DM患者发生营养风险影响因素的logistic回归分析

Table 3. Logistic regression analysis of factors influencing nutritional risk in T2DM patients

变量	B	SE	Waldχ²	P值	OR(95% CI)
血红蛋白	0.101	0.031	10.632	0.001	1.107(1.041~1.176)
白蛋白	0.191	0.071	7.121	0.008	1.210(1.052~1.392)
尿素氮	0.000	0.003	0.020	0.888	1.000(0.995~1.006)
肌酐	-0.254	0.053	22.600	< 0.001	0.776(0.698~0.861)

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