A bibliometric-based study on the progress in traditional Chinese medicine for the treatment of bronchial asthma over the past decade
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摘要:
目的 支气管哮喘是临床常见的慢性气道炎症性疾病，中医药在其防治方面具有独特优势。本研究旨在通过文献计量学方法系统分析近10年来中医药治疗支气管哮喘的研究现状、热点及发展趋势，为后续研究提供参考依据。 方法 检索2014年1月—2023年12月中国知网(CNKI)收录的4 302篇相关文献，运用CiteSpace 6.2.R4软件对作者、机构及关键词进行文献计量学分析并绘制知识图谱。 结果 年发文量总体呈上升趋势，赵霞-李竹英团队贡献显著，黑龙江中医药大学与北京中医药大学为本研究领域核心机构。分析后得到613个关键词、8个关键词聚类图谱及20个突现词。中医药治疗哮喘研究的主要热点集中在穴位贴敷治疗小儿哮喘研究、中医药治疗哮喘的临床疗效研究、中医药对哮喘免疫功能的影响与机制研究等3个方面，且近几年产生了大量新的研究主题及关键词，如网络药理学、中医传承辅助平台、分子对接、麻黄、外寒内饮证、冷哮证、炎症、哮喘控制测试、肺脾气虚型等。 结论 通过知识图谱直观地呈现出中医药治疗支气管哮喘的研究现状、热点以及未来研究趋势，近几年来，研究内容不再拘泥于中医药的临床疗效，更侧重于临床应用创新、疗效比较、用药规律、数据挖掘、信号通路等的研究，这是我国近年来促进中医药传承与创新的生动体现，为支气管哮喘的中医诊疗和相关研究提供临床思路。 Abstract:Objective Bronchial asthma is a clinically prevalent chronic inflammatory airway disease, in which traditional Chinese medicine (TCM) has demonstrated distinctive advantages in both prevention and treatment. This study aims to systematically analyze the research status, hotspots, and development trends of TCM in treating bronchial asthma over the past decade using bibliometric methods, thereby providing a reference for subsequent research. Methods We retrieved 4 302 relevant articles published between January 2014 and December 2023 from the China National Knowledge Infrastructure (CNKI) database. Using CiteSpace 6.2.R4 software, we conducted a bibliometric analysis of authors, institutions, and keywords, and generated knowledge maps. Results The annual publication volume showed an overall upward trend, with the Zhao Xia-Li Zhuying research team making significant contributions. Heilongjiang University of Chinese Medicine and Beijing University of Chinese Medicine were identified as the core institutions in this field. The analysis revealed 613 keywords, 8 keyword clusters, and 20 burst terms. The primary research hotspots in the TCM treatment of asthma focused on three key areas: (1) acupoint application therapy for pediatric asthma; (2) clinical efficacy studies of TCM in asthma treatment; (3) investigations into the effects and mechanisms of TCM on immune function in asthma. In recent years, new research themes and emerging keywords have included network pharmacology, TCM inheritance support system, molecular docking, Ephedra sinica, "external cold with internal fluid retention" syndrome, "cold wheezing" syndrome, inflammation, asthma control test (ACT), and lung-spleen qi deficiency pattern. Conclusion The knowledge maps provide a visual representation of the research landscape, hotspots, and future trends in the TCM treatment of bronchial asthma. Recent research has gradually evolved from focusing on clinical efficacy to encompassing clinical application innovation, comparative effectiveness studies, medication patterns, data mining, and signal pathways. This reflects China's growing efforts to promote the inheritance and innovation of TCM, providing valuable clinical insights for the diagnosis, treatment, and future research of bronchial asthma in TCM practice. -
Key words:
- Bronchial asthma /
- Traditional Chinese medicine /
- Bibliometrics /
- Visualization analysis
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图 1 2014—2023年中医药治疗哮喘研究文献数量及趋势
Figure 1. Number and trend of research literature on Chinese medicine for asthma, 2014-2023
图 2 2014—2023年中医药治疗哮喘研究作者发文及合作分布
Figure 2. Distribution of research authors ' publications and collaborations in Chinese medicine for asthma, 2014-2023
图 3 2014—2023年中医药治疗哮喘研究机构发文及合作分布
Figure 3. Distribution of publications and collaborations of research organizations on Chinese medicine for asthma, 2014-2023
图 4 2014—2023年中医药治疗哮喘研究关键词共现图谱
Figure 4. Keyword co-occurrence mapping of research on Chinese medicine for asthma, 2014-2023
图 5 2014—2023年中医药治疗哮喘研究关键词聚类图谱
Figure 5. Keyword clustering in research on Chinese medicine for asthma, 2014-2023
图 6 2014—2023年中医药治疗哮喘研究关键词时间线图谱
Figure 6. Timeline mapping of keywords for research on Chinese medicine for asthma, 2014-2023
表 1 2014—2023年中医药治疗哮喘研究突现词统计
Table 1. Keyword burst analysis in traditional Chinese medicine research on asthma, 2014-2023
Keywords Year Strength Begin End 2014—2023 护理 2014 4.35 2014 2016 ▃▃▃▂▂▂▂▂▂▂ 辨证分型 2014 3.07 2014 2016 ▃▃▃▂▂▂▂▂▂▂ 学术性 2014 3.07 2014 2016 ▃▃▃▂▂▂▂▂▂▂ 天灸疗法 2014 2.84 2014 2016 ▃▃▃▂▂▂▂▂▂▂ 效果 2014 5.18 2015 2018 ▂▃▃▃▃▂▂▂▂▂ 随机对照试验 2015 4.04 2015 2017 ▂▃▃▃▂▂▂▂▂▂ 肿瘤坏死因子-α 2016 3.03 2016 2018 ▂▂▃▃▃▂▂▂▂▂ 中医治疗 2014 2.94 2016 2018 ▂▂▃▃▃▂▂▂▂▂ 代谢组学 2017 3.34 2017 2020 ▂▂▂▃▃▃▃▂▂▂ 用药规律 2015 7.82 2019 2023 ▂▂▂▂▂▃▃▃▃▃ 肺脾气虚型 2019 3.13 2019 2021 ▂▂▂▂▂▃▃▃▂▂ 呼出气一氧化氮 2017 2.83 2019 2023 ▂▂▂▂▂▃▃▃▃▃ 补肺益肾汤 2019 2.73 2019 2021 ▂▂▂▂▂▃▃▃▂▂ 中医传承辅助平台 2019 2.73 2019 2021 ▂▂▂▂▂▃▃▃▂▂ 数据挖掘 2017 9.97 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 中医证候积分 2018 9.12 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 炎性因子 2017 8.40 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 针刺疗法 2016 3.62 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 气道炎症 2015 3.50 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 冷哮证 2020 2.86 2020 2023 ▂▂▂▂▂▂▃▃▃▃ 
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