肺癌患者治疗间歇期静态行为现状及影响因素分析

袁妞; 裘文娟; 周云仙; 张如卉

doi:10.16766/j.cnki.issn.1674-4152.004553

肺癌患者治疗间歇期静态行为现状及影响因素分析

doi: 10.16766/j.cnki.issn.1674-4152.004553

1.
浙江大学医学院附属第一医院护理部，浙江杭州 310003
2.
浙江中医药大学护理学院，浙江杭州 310053
3.
浙江大学医学院附属第一医院呼吸内科

基金项目:

浙江省教育厅一般科研项目 Y202353909

详细信息

通讯作者:
周云仙，E-mail：1193138211@qq.com

中图分类号: R734.2 R473.73
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- 文章访问数: 7
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出版历程
- 收稿日期: 2025-07-10
- 网络出版日期: 2026-11-10

Current status and influencing factors of sedentary behavior during treatment intervals in lung cancer patients

1.
Department of Nursing, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China

摘要

摘要: 目的了解肺癌患者治疗间歇期静态行为现状及影响因素，为今后制定针对性干预方案提供参考。方法便利抽取2024年4—7月在浙江大学医学院附属第一医院就诊的310例肺癌患者，运用一般资料调查表、中国成人静态行为问卷、日常生活活动能力Barthel指数、疼痛数字评定量表、呼吸困难改良量表、医院焦虑抑郁量表、领悟社会支持量表、Tilburg衰弱量表进行问卷调查。采用二元logistic回归分析研究肺癌患者治疗间歇期静态行为的影响因素。结果共回收有效问卷308份。调查结果显示，肺癌患者治疗间歇期静态行为时间为6.25（4.50, 7.50）h。二元logistic回归分析结果显示, 肺癌类型（OR=2.408，95% CI：1.251~4.695，P=0.009）、日常生活活动能力（OR=0.961，95% CI：0.937~0.984，P=0.001）、焦虑抑郁（OR=1.033，95% CI：1.004~1.065，P=0.028）、领悟社会支持（OR=0.971，95% CI：0.948~0.993，P=0.011）与衰弱（OR=3.225，95% CI：1.891~ 5.605，P < 0.001）均是肺癌患者治疗间歇期静态行为的影响因素。结论肺癌患者治疗间歇期静态行为时间较长，未来可根据影响因素制定干预方案，改善患者静态行为。
- 肺癌 /
- 静态行为 /
- 影响因素
Abstract: Objective To investigate the current status and influencing factors of sedentary behavior during the treatment intermission in lung cancer patients, providing a reference for the development of targeted intervention strategies in the future. Methods A convenient sampling method was employed to select 310 lung cancer patients who visited the First Affiliated Hospital of Zhejiang University School of Medicine from April to July 2024. Data were collected through a series of questionnaires, including a general information questionnaire, the Chinese version of the adult sedentary behavior questionnaire, the Barthel Index for activities of daily living, numerical rating scale for pain, modified Medical Research Council scale, hospital anxiety and depression scale, perceived social support scale, and the Tilburg frailty indicator. Binary logistic regression was used to identify the factors influencing sedentary behavior during the treatment intermission in lung cancer patients. Results A total of 308 valid questionnaires were collected. The survey results revealed that the time spent on sedentary behavior during the treatment intermission was 6.25 (4.50, 7.50) hours. Binary logistic regression analysis identified lung cancer type (OR=2.408, 95% CI: 1.251-4.695, P=0.009), activities of daily living (OR=0.961, 95% CI: 0.937-0.984, P=0.001), anxiety and depression (OR=1.033, 95% CI: 1.004-1.065, P=0.028), perceived social support (OR=0.971, 95% CI: 0.948-0.993, P=0.011), and frailty (OR=3.225, 95% CI: 1.891-5.605, P < 0.001) as significant factors influencing sedentary behavior during the treatment intermission in lung cancer patients. Conclusion Lung cancer patients exhibit prolonged sedentary behavior during the treatment intermission. Based on these influencing factors, future intervention strategies can be designed to address and improve sedentary behavior in this patient population.
- Lung cancer /
- Sedentary behavior /
- Influencing factors

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图 1 肺癌患者治疗间歇期SBQ时间

Figure 1. The SBQ time for lung cancer patients during the treatment interval

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表 1 肺癌患者治疗间歇期静态行为的单因素分析

Table 1. Univariate analysis of sedentary behavior in patients with lung cancer during the treatment interval

项目	静态行为组(n=192)	非静态行为组(n=116)	统计量	P值
性别[例(%)]			0.849^a	0.358
男性	151(78.65)	97(83.62)
女性	41(21.35)	19(16.38)
年龄[M(P₂₅, P₇₅), 岁]	67.00(61.00, 72.00)	64.50(57.75, 68.25)	3.755^b	＜0.001
婚姻状况[例(%)]			0.394^a	0.530
已婚	181(94.27)	112(96.55)
单身	11(5.73)	4(3.45)
文化程度[例(%)]			1.709^b	0.087
文盲	40(20.83)	14(12.07)
小学	96(50.00)	61(52.59)
初中	44(22.92)	34(29.31)
高中	8(4.17)	4(3.45)
专科	3(1.56)	2(1.72)
本科及以上	1(0.52)	1(0.86)
居住地[例(%)]			0.030^a	0.863
农村	101(52.60)	63(54.31)
城镇	91(47.40)	53(45.69)
居住方式[例(%)]			7.405^a	0.025
独居	32(16.67)	7(6.03)
与配偶居住	112(58.33)	77(66.38)
与配偶子女居住	48(25.00)	32(27.59)
BMI[M(P₂₅, P₇₅)]	21.64(19.89, 24.14)	22.61(20.05, 24.93)	1.300^b	0.194
肺癌类型[例(%)]			8.117^a	0.004
小细胞肺癌	29(15.1)	34(29.31)
非小细胞肺癌	163(84.9)	82(70.69)
肺癌分期[例(%)]			1.427^b	0.154
Ⅰ期	10(5.21)	11(9.48)
Ⅱ期	39 (20.13)	29(25.00)
Ⅲ期	67 (34.90)	35(30.17)
Ⅳ期	76 (39.58)	41(35.34)
病程[例(%)]			0.482^b	0.629
≤1年	81(42.19)	50(43.10)
>1~3年	78(40.62)	50(43.10)
>3~5年	12(6.25)	8(6.90)
>5~10年	11(5.73)	4(3.45)
>10年	10(5.21)	4(3.45)
继发胸腔积液[例(%)]	46(23.96)	19(16.38)	2.060^a	0.151
继发心包积液[例(%)]	18(23.96)	7(6.03)	0.680^a	0.409
继发脑转移[例(%)]	51(26.56)	25(21.55)	0.726^a	0.394
继发静脉血栓栓塞症[例(%)]	28(14.58)	14(12.07)	0.204^a	0.652
继发骨转移[例(%)]	43(22.4)	18(15.52)	1.743^a	0.187
继发周围神经病[例(%)]	35(18.23)	26(22.41)	0.556^a	0.456
合并心血管疾病[例(%)]	65(33.85)	48(41.38)	1.454^a	0.228
BI评分[M(P₂₅, P₇₅), 分]	72.50(55.00, 85.00)	85.00(75.00, 90.00)	6.217^b	＜0.001
NRS评分[M(P₂₅, P₇₅), 分]	1.00(0.00, 2.00)	0.00(0.00, 2.00)	1.948^b	0.051
mMRC评分[M(P₂₅, P₇₅), 分]	2.00(2.00, 3.00)	2.00(2.00, 2.00)	4.784^b	＜0.001
HADS评分[M(P₂₅, P₇₅), 分]	20.50(12.75, 27.00)	15.00(7.00, 23.00)	3.325^b	＜0.001
PSSS评分[M(P₂₅, P₇₅), 分]	42.00(34.00, 54.00)	49.00(42.00, 58.00)	4.484^b	＜0.001
TFI评分[M(P₂₅, P₇₅), 分]	3.00(2.00, 3.00)	2.00(2.00, 3.00)	5.739^b	＜0.001
注：^a为χ²值，^b为Z值。

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表 2 肺癌患者静态行为的单因素和多因素分析

Table 2. Univariate and multivariate analysis of sedentary behavior in patients with lung cancer

变量	单因素		多因素
变量	OR(95% CI)	P值	OR(95% CI)	P值
年龄	1.055(1.025~1.086)	＜0.001	1.030(0.994~1.068)	0.104
肺癌类型	2.331(1.331~4.110)	0.003	2.408(1.251~4.695)	0.009
BI评分	0.950(0.933~0.966)	＜0.001	0.961(0.937~0.984)	0.001
NRS评分	1.272(1.017~1.603)	0.038	1.099(0.812~1.494)	0.543
mMRC评分	2.087(1.530~2.909)	＜0.001	0.936(0.603~1.457)	0.766
HADS评分	1.040(1.015~1.066)	0.002	1.033(1.004~1.065)	0.028
PSSS评分	0.956(0.938~0.974)	＜0.001	0.971(0.948~0.993)	0.011
TFI评分	3.877(2.442~6.259)	＜0.001	3.225(1.891~5.605)	＜0.001
注：单因素分析仅列出差异有统计学意义的变量。

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