偏头痛患者认知功能状况及与焦虑、抑郁的相关性研究

王静; 胡艳丽; 朱书渊; 彭述珊; 叶小芳; 曹江; 王铁虎

doi:10.16766/j.cnki.issn.1674-4152.003598

偏头痛患者认知功能状况及与焦虑、抑郁的相关性研究

doi: 10.16766/j.cnki.issn.1674-4152.003598

1.
丽水市第二人民医院心身科，浙江丽水 323000
2.
湖州市第三人民医院精神科，浙江湖州 313000

基金项目:

浙江省医药卫生科技计划项目 2018KY787

浙江省丽水市公益性技术研究项目 2019SJZC56

详细信息

通讯作者:
胡艳丽，E-mail：gongxigxfc@163.com

中图分类号: R747.2
计量
- 文章访问数: 95
- HTML全文浏览量: 59
- PDF下载量: 6
- 被引次数: 0
出版历程
- 收稿日期: 2023-04-20
- 网络出版日期: 2024-09-05

Cognitive function of migraine patients and its correlation with anxiety and depression

1.
Psychosomatic Department, the Second People ' s Hospital of Lishui, Lishui, Zhejiang 323000, China

摘要

摘要: 目的对偏头痛患者的认知功能状况进行分析，并探讨认知功能障碍与焦虑和抑郁的相关性。方法选取丽水市第二人民医院心身科2022年1月—2023年1月收治的偏头痛患者165例，根据蒙特利尔认知功能评估量表(MoCA)将患者分为认知功能下降组(MoCA评分＜26分)42例和认知功能正常组(MoCA评分≥26分)123例。比较2组认知功能状况及焦虑、抑郁程度，并分析认知功能障碍与焦虑、抑郁之间的相关性。结果 165例患者中出现认知功能下降共42例，占25.45%。认知功能下降组MoCA评分明显低于认知功能正常组[(23.52±2.16)分vs. (27.79±2.85)分，t=8.872，P＜0.001]，而焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、视觉模拟(VAS)评分、头痛影响测评量表-6(HIT-6)评分均明显高于认知功能正常组(P＜0.05)。Spearman相关性分析显示，MoCA评分与SAS评分、SDS评分均呈正相关关系(r值分别为0.468、0.492，均P＜0.001)。结论偏头痛患者存在认知功能障碍的比例较高，伴有认知功能障碍的患者其头痛程度更明显，且对日常生活质量造成的影响更大。偏头痛认知功能障碍与焦虑、抑郁呈正相关关系。
- 偏头痛 /
- 认知功能 /
- 焦虑 /
- 抑郁 /
- 相关性
Abstract: Objective To analyze the cognitive function of migraine patients and explore the correlation between cognitive dysfunction and anxiety and depression. Methods A total of 165 migraine patients admitted to the Department of Psychosomatic of the Second People ' s Hospital of Lishui from Jan.2022 to Jan.2023 were selected. According to the Montreal cognitive function assessment scale (MoCA), the patients were divided into the cognitive function decline group (42 cases, MoCA score < 26 points) and the cognitive function normal group (123 cases, MoCA score ≥26 points). The cognitive function of the two groups and the degree of anxiety and depression were compared, and the correlation between cognitive dysfunction and anxiety and depression was analyzed. Results Among the 165 patients, cognitive function decreased in 42 cases, accounting for 25.45%. The MoCA score of the group with declining cognitive function was significantly lower than that of the group with normal cognitive function [(23.52±2.16) points vs. (27.79±2.85) points, t=8.872, P < 0.001]. The scores of the self-rating anxiety scale (SAS), self-rating depression scale (SDS), visual analogue scale (VAS), and headache impact assessment scale-6 (HIT-6) were significantly higher than those of the normal cognitive function group (P < 0.05), respectively. Spearman correlation analysis showed that the MoCA score was positively correlated with the SAS score and SDS score (r values were 0.468 and 0.492, respectively, all P < 0.001). Conclusion The proportion of migraine patients with cognitive dysfunction is higher, and the degree of headache is more obvious in patients with cognitive dysfunction and has a greater impact on the quality of daily life. The cognitive dysfunction of migraine is positively correlated with anxiety and depression.
- Migraine /
- Cognitive function /
- Anxiety /
- Depression /
- Correlation

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表 1 2组偏头痛患者一般情况比较

Table 1. Comparison of general conditions between two groups in migraine patients

组别	例数	性别(例)		年龄(x ±s，岁)	病程(x ±s，年)	发作频率(x ±s，次/月)
组别	例数	男性	女性	年龄(x ±s，岁)	病程(x ±s，年)	发作频率(x ±s，次/月)
认知功能下降组	42	25	17	42.92±2.68	5.76±1.28	4.28±0.78
认知功能正常组	123	62	61	42.88±2.79	5.81±1.29	4.13±0.87
统计量		1.044^a		0.081^b	0.217^b	0.989^b
P值		0.307		0.936	0.828	0.324
注：^a为χ²值，^b为t值。

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表 2 2组偏头痛患者焦虑、抑郁状况比较(x ±s，分)

Table 2. Comparison of anxiety and depression between two groups in migraine patients (x ±s, points)

组别	例数	MoCA评分	SAS评分	SDS评分	VAS评分	HIT-6评分
认知功能下降组	42	23.52±2.16	55.72±4.71	58.21±5.62	7.83±1.78	61.58±5.76
认知功能正常组	123	27.79±2.85	52.81±3.85	53.61±4.26	6.91±1.69	57.92±5.89
t值		8.872	3.988	5.547	3.005	3.496
P值		＜0.001	＜0.001	＜0.001	0.003	＜0.001

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