Effect of Yiqi Shengjiang Decoction assisted therapy on postoperative function of patients with colon cancer

Objective To investigate the effect of Yiqi Shengjiang Decoction on gastrointestinal motility, immune function and quality of life in patients with colon cancer. Methods A total of 178 patients with postoperative colon cancer who were treated in our hospital from January 2016 to January 2018 were randomly divided into two groups, 89 cases in each group. The control group was given XELOX regimen chemotherapy, and the observation group was supplemented with Yiqi Shengjiang Decoction on the basis of the control group, both groups were treated for 3 cycles. After treatment, the changes of gastrointestinal motility recovery (first bowel sound time, anal exhaust time, defecation time, hospital stay) and immune function (CD3⁺, CD4⁺, CD8⁺, CD4⁺/CD8⁺) and peripheral blood cell levels (RBC, WBC, PLT, HB), quality of life (SF-36) were compared between the two groups. Results The first bowel sound time, anal exhaust time, defecation time and hospital stay in the observation group were significantly lower than those in the control group (all P<0.05). After treatment, the levels of CD3⁺, CD4⁺, CD8⁺ and CD4⁺/CD8⁺ in the control group did not change significantly (all P>0.05), the levels of CD3⁺, CD4⁺ and CD4⁺/CD8⁺ in the observation group were significantly increased (all P<0.05), and the level of CD4⁺ was significantly decreased (P<0.05), and all of them were significantly better than the control group (all P<0.05). After treatment, the levels of RBC, WBC, PLT and HB in the observation group did not decrease significantly (all P>0.05), and the levels of RBC, WBC, PLT and HB in the control group decreased significantly (all P<0.05), and the observation group was significantly higher than the control group (all P<0.05). After treatment, the physiological function, psychological function, physical pain, health status, social function, energy, mental health and emotional function scores of the two groups were significantly increased (all P<0.05), and the observation group was significantly higher than the control group (all P<0.05). Conclusion Yiqi Shengjiang Decoction can significantly promote the recovery of gastrointestinal motility in patients with postoperative colon cancer, enhance the immune function of patients, reduce the hematological toxicity of patients after chemotherapy, and thus help to improve the patients' quality of life.