Volume 19 Issue 2
Feb.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(2): 293-297
WANG Xi, AN Song-tao, LI Wen-bo, CHEN Dong-chang, MENG Hua. Research progress of the effect of SARS-CoV-2 on the circulatory system[J]. Chinese Journal of General Practice, 2021, 19(2): 293-297. doi: 10.16766/j.cnki.issn.1674-4152.001792
Citation: WANG Xi, AN Song-tao, LI Wen-bo, CHEN Dong-chang, MENG Hua. Research progress of the effect of SARS-CoV-2 on the circulatory system[J]. Chinese Journal of General Practice, 2021, 19(2): 293-297. doi: 10.16766/j.cnki.issn.1674-4152.001792
shu

Research progress of the effect of SARS-CoV-2 on the circulatory system

doi: 10.16766/j.cnki.issn.1674-4152.001792
  • 1.

    Department of Cardiology, Hennan University People's Hospital, Henan Provincial People's Hospital, Henan, Zhengzhou 450003, China

Funds:

 81970312

 182300410304

  • Received Date: 2020-08-15
    Available Online: 2022-02-19
    Abstract
  • Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus (SARS-CoV-2). It is a disease that can spread widely amongst the population with fever, cough, and dyspnea as the main clinical symptoms. To date, SARS-CoV-2 is causing a pandemic. With the effective development of domestic epidemic prevention and control and the understanding and research of the new type of coronavirus pneumonia, many patients with new coronary pneumonia have been discovered to have clinical symptoms that are first or secondary to symptoms of circulatory system damage. SARS-CoV-2 can directly damage cardiomyocytes through angiotensin converting enzyme 2 receptors. It can also activate the immune system abnormally and release a large number of cytokines to cause acute and chronic myocardial damage. When the heart function is severely impaired, kidney function may be affected through the RAS system, which may lead to clinical manifestations of heart and kidney damage at the same time. For COVID-19 patients, risks of arterial and venous thromboembolism also exist. This article combines the data of the new coronary pneumonia cases announced in recent days and the latest findings of research teams to provide a brief overview of the study progress of the new coronavirus on the circulatory system. We aim to better elucidate the damage to the circulatory system caused by the new coronavirus infection.

     

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