Volume 19 Issue 3
Mar.  2021
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YANG Di, HUANG Yu-hong, ZHANG Bin. Application value of white blood cell, C-reactive protein and hematocrit in adult acute infectious diarrhea[J]. Chinese Journal of General Practice, 2021, 9(3): 375-378. doi: 10.16766/j.cnki.issn.1674-4152.001814
Citation: YANG Di, HUANG Yu-hong, ZHANG Bin. Application value of white blood cell, C-reactive protein and hematocrit in adult acute infectious diarrhea[J]. Chinese Journal of General Practice, 2021, 9(3): 375-378. doi: 10.16766/j.cnki.issn.1674-4152.001814
shu

Application value of white blood cell, C-reactive protein and hematocrit in adult acute infectious diarrhea

doi: 10.16766/j.cnki.issn.1674-4152.001814

  • Department of Infectious Diseases, the Third People's Hospital of Hefei, Hefei, Anhui 230022, China

Funds:

 1708085MH0117

  • Received Date: 2020-03-26
    Available Online: 2022-02-19
    Abstract
  •   Objective  To explore the application value of white blood cell (WBC), C-reactive protein (CRP) and hematocrit (HCT) in adult's acute infectious diarrhea.  Methods  A total of 90 patients with acute infectious diarrhea admitted to our hospital from April 2014 to October 2018 were collected. According to the dehydration symptoms caused by the disease, they were divided into three groups of mild, medium and severe group (30 cases each). All patients were treated with antibiotics. WBC, CRP, HCT, abdominal pain, nausea and vomiting, fever and fatigue were examined before and after treatment. Pearson's method was used to analyze the relationship among the three indexes, dehydration degree and antidiarrheal time.  Results  The differences of WBC, CRP and HCT in the three groups before treatment were statistically significant (F=23.092, 3.998, 8.905, all P < 0.05). Among them, the WBC, CRP and HCT levels were the lowest in the mild group and the highest in the severe group (P < 0.05). The differences of WBC, CRP and HCT in the three group after treatment were statistically significant (F=13.966, 4.031, 5.435, all P < 0.05). Among them, the WBC, CRP and HCT levels were the lowest in the mild group, and the highest in the severe group (P < 0.05). The antidiarrheal time [(10.57±4.36) d] and antibiotic treatment time [(10.71±3.92) d] were the longest in the severe group, and the incidence of abdominal pain, nausea and vomiting, fever and fatigue were the highest in the severe group (P < 0.05). WBC was positively correlated with dehydration degree and antidiarrheal time (r=0.767, 0.813, all P < 0.05), CRP was positively correlated with dehydration degree and antidiarrheal time (r=0.829, 0.802, all P < 0.05), HCT was positively correlated with dehydration degree and antidiarrheal time (r=0.886, 0.823, all P < 0.05).  Conclusion  WBC, CRP and HCT can predict the dehydration degree and prognosis of patients with negative bacterial culture, and provide reference for guiding treatment and avoiding excessive use of antibiotics.

     

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