Volume 19 Issue 3
Mar.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(3): 398-401
SHENG Jing, YAN Ying-zhao, SUN Yu, QU Hang-bo, HUANG Xiao-qin. The efficacy and safety of transdermal buprenorphine patch for postoperative analgesia after arthroscopic rotator cuff repair[J]. Chinese Journal of General Practice, 2021, 19(3): 398-401. doi: 10.16766/j.cnki.issn.1674-4152.001820
Citation: SHENG Jing, YAN Ying-zhao, SUN Yu, QU Hang-bo, HUANG Xiao-qin. The efficacy and safety of transdermal buprenorphine patch for postoperative analgesia after arthroscopic rotator cuff repair[J]. Chinese Journal of General Practice, 2021, 19(3): 398-401. doi: 10.16766/j.cnki.issn.1674-4152.001820
shu

The efficacy and safety of transdermal buprenorphine patch for postoperative analgesia after arthroscopic rotator cuff repair

doi: 10.16766/j.cnki.issn.1674-4152.001820

  • Department of Orthopaedic Surgery, Zhejiang Hospital, Hangzhou, Zhejiang 310030, China

Funds:

 2020ZA001

  • Received Date: 2020-02-18
    Available Online: 2022-02-19
    Abstract
  •   Objective  To explore the effect of transdermal buprenorphine patch (TBP) for postoperative analgesia after arthroscopic rotator cuff repair (ARCR) and to count the incidence of adverse drug reactions (ADR).  Methods  The clinical data of patients (30 cases in each group) who did not receive and received buprenorphine transdermal patch after ARCR under arthroscope in Zhejiang hospital from October 2017 to October 2019 were retrospectively analyzed. Group A were only treated with flurbiprofen axetil (FA) 100 mg twice a day for 5 days postoperatively. Group B were treated with FA as in A group postoperatively and 5mg TBP for 14 days (from 1 day before operation). The visual analogue score (VAS) of each group was tracked 1 day before operation and 1, 2, 3, 5 and 14 day after operation, and the incidence of ADR was counted. The simple shoulder test score (SST), range of shoulder forward elevation (FE) and external rotation (ER) were recorded, and compared between the same patients preoperatively and postoperatively and compared also between two groups.The statistical data was analyzed with t-test, analysis of variance and chi-squared test.  Results  On 3, 5 and 14 day after operation, the VAS of group B was lower than that of group A (P < 0.05).At 12 weeks follow-up, compared with preoperative values, the VAS, SST, FE and ER of two groups were significantly improved (P < 0.05). At 12 weeks, group B showed a larger FE range compared with group A (P < 0.05), while the difference of VAS, SST and ER between two groups had no statistical significance. The ADR of group A and group B was 2/30 (6.67%) and 5/30 (16.67%). No significant difference was found between two groups.  Conclusion  TBP has good effect for postoperative analgesia after ARCR and does not delay the recovery of shoulder joint function.

     

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