Volume 19 Issue 3
Mar.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(3): 425-427, 431
CHEN Qing-hong, YANG Lin-lin. Study on the outcome of glucose metabolism and related factors in gestational diabetes mellituss at 6-12 weeks postpartum[J]. Chinese Journal of General Practice, 2021, 19(3): 425-427, 431. doi: 10.16766/j.cnki.issn.1674-4152.001827
Citation: CHEN Qing-hong, YANG Lin-lin. Study on the outcome of glucose metabolism and related factors in gestational diabetes mellituss at 6-12 weeks postpartum[J]. Chinese Journal of General Practice, 2021, 19(3): 425-427, 431. doi: 10.16766/j.cnki.issn.1674-4152.001827
shu

Study on the outcome of glucose metabolism and related factors in gestational diabetes mellituss at 6-12 weeks postpartum

doi: 10.16766/j.cnki.issn.1674-4152.001827
  • 1.

    Department of Obstetrics and Gynecology, Cixi People's Hospital, Cixi, Zhejiang 315300, China

Funds:

 2018RC064

 20191CXS010035

  • Received Date: 2020-05-25
    Available Online: 2022-02-19
    Abstract
  •   Objective  To discuss the effects of glucose metabolism and related factors in gestational diabetes mellitus (GDM) patients at 6-12 weeks postpartum on GDM and to provide theoretical reference for preventing abnormal glucose metabolism in GDM patients.  Methods  GDM inpatients who met the requirements in our hospital from January 2019 to January 2020 were selected for the study and divided into the abnormal glucose metabolism group (80 cases) and normal glucose metabolism group (120 cases) on the basis of the results of 6-12 weeks postpartum glucose metabolism. Pre-pregnancy, mid-pregnancy and neonatal-related indicators were compared and analysed between the two groups.  Results  Univariate analysis showed that GDM patients had significant differences in age, family history of diabetes, pre-pregnancy BMI, oral glucose tolerance test (OGTT) FPG and OGTT 2hPG; all the differences were statistically significant (P < 0.05). Multivariate analysis showed that age (OR=2.177, P=0.002), pre-pregnancy BMI (ORfat=3.062, P=0.001; ORoverweight=0.038, P=0.036) and family history of diabetes (OR=6.968, P=0.030)were independent risk factors for glucose metabolism abnormalities in GDM patients at 6-12 weeks postpartum.  Conclusion  Abnormal postpartum glucose metabolism in GDM patients may be related to patient's age, family history of diabetes and BMI before pregnancy. Clinicians should be alert to the relevant risk factors during diagnosis and treatment, and follow-up and preventive and control measures should be taken to reduce the incidence of postpartum glucose metabolism abnormalities in GDM patients.

     

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