Volume 19 Issue 6
Jun.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(6): 1043-1045,1064
WANG Le-le, HAN Xu, ZHANG Qi, CHEN Xin. Epidemiological investigation and clinical symptom analysis of influenza among children in a hospital of Bengbu City from 2018 to 2019[J]. Chinese Journal of General Practice, 2021, 19(6): 1043-1045,1064. doi: 10.16766/j.cnki.issn.1674-4152.001980
Citation: WANG Le-le, HAN Xu, ZHANG Qi, CHEN Xin. Epidemiological investigation and clinical symptom analysis of influenza among children in a hospital of Bengbu City from 2018 to 2019[J]. Chinese Journal of General Practice, 2021, 19(6): 1043-1045,1064. doi: 10.16766/j.cnki.issn.1674-4152.001980
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Epidemiological investigation and clinical symptom analysis of influenza among children in a hospital of Bengbu City from 2018 to 2019

doi: 10.16766/j.cnki.issn.1674-4152.001980
  • 1.

    Department of Pediatrics, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2019A0378

  • Received Date: 2020-10-21
    Available Online: 2022-02-16
    Abstract
  •   Objective  To analyse the epidemiological characteristics and clinical symptoms of influenza among children in a hospital of Bengbu City from 2018 to 2019 so as to provide basis for the prevention and treatment of influenza.  Methods  A total of 528 children diagnosed with influenza and hospitalised in the First People's Hospital in Bengbu from January 2018 to December 2019 were selected as the research objects. The medical history data of the children were reviewed and statistically analysed along with the epidemiological characteristics, clinical symptoms and laboratory tests.  Results  Among the 528 children with influenza, 21.3% had influenza A, 55.6% had influenza B and 23.1% had influenza A combined with influenza B. The peak age of influenza was 1-7 years old and 7-14 years old, and the lowest was among the 0-1 year old infants. Among them, the incidence rate of influenza increased with age, regardless of gender. No significant difference was noted in the incidence rate (P=0.326). The high incidence season of influenza among children was from November to December to March of the next year. The high incidence age of school-age children was 3-7 years old. The clinical symptoms of fever, sore throat, diarrhoea, headache and other clinical symptoms of children with influenza A were severe, the hospitalization time was long, the fever lasted for a long time and the complications were more. In addition, the test indexes of white blood cell, calcitonin and C-reactive protein were significantly increased (all P < 0.05).  Conclusion  The influenza outbreak of children in Bengbu City is seasonal. The number of patients with influenza B is more than those with influenza A and influenza A combined with influenza B. The clinical symptoms and organ damage of children with influenza A are significantly more serious than those with mixed influenza A and B. The hospitalization time and fever duration of children with influenza A are longer than those with influenza B and mixed infection.

     

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    • References(18)
  • [1]
    WHO. Influenza(Seasonal)[EB/OL]. (2014-03-01)[2016-8-20]. DOI: 10.13140/RG.2.2.33938.07364.
    [2]
    MANCINELLI L, ONORI M, CONCATO C, et al. Clinical features of children hospitalized with influenza A and B infections during the 2012-2013 influenza season in Italy[J]. BMC Infect Dis, 2015, 16(1): 6-13. doi: 10.1186/s12879-015-1333-x
    [3]
    张爱君. 流行性感冒病毒[J]. 中国地方病防治杂志, 2009, 3(1): 172. https://www.cnki.com.cn/Article/CJFDTOTAL-DYBF200903007.htm
    [4]
    IULIANO A D, ROGUSKI K M, CHANG H H, et al. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study[J]. Lancet, 2018, 391(10127): 1285-1300. doi: 10.1016/S0140-6736(17)33293-2
    [5]
    中华医学会儿科学分会呼吸学组, 《中华实用儿科临床杂志》编辑委员会. 儿童流感诊断与治疗专家共识(2020年版)[J]. 中华实用儿科临床杂志, 2020, 35(17): 1281-1287. doi: 10.3760/cma.j.cn101070-20200224-00240
    [6]
    PAN Y, ZHANG Y, YANG P, et al. Epidemiological and phylogenetic charachteristics of influenza B infection in severe acute respiratory infection cases in Beijing, 2014 to 2015[J]. Medicine(Baltimore), 2015, 94(52): e2399. http://pdfs.semanticscholar.org/a0c6/9f6fb4e43a1837ebdef39bfe1547cee14274.pdf
    [7]
    ZIMMERMAN R K, RINALDO C R, NOWALK M P, et al. Viral infections in outpatients with medically attended acute respiratory illness during the 2012-2013 influenza season[J]. BMC Infect Dis, 2015, 15: 87. doi: 10.1186/s12879-015-0806-2
    [8]
    张幕丽, 彭质斌, 郑建东, 等. 中国儿童流感疾病负担和疫苗应用现状[J]. 中华实用儿科临床杂志, 2019, 34(2): 91-97.
    [9]
    张惺惺, 吴双胜, 王全意, 等. 北京市2017-2018流行季节流感感染率和发病率研究[J]. 国际病毒性杂志, 2019, 26(2): 73-76.
    [10]
    IULIANO A D, ROGUSKI K M, CHANG H H, et al. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study[J]. Lancet, 2018, 391(1127): 1285-1300. http://smartsearch.nstl.gov.cn/paper_detail.html?id=90b77c8d3ff1394c557b857d277e220c
    [11]
    LIU T, LI Z, ZHANG S, et al. Viral etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China[J]. Virol J, 2015, 12: 168. doi: 10.1186/s12985-015-0388-z
    [12]
    FU Y, PAN L, SUN Q, et al. The clinical and etiological characteristics of influenza-like illness in outpatients in Shanghai, China, 2011 to 2013[J]. PLoS One, 2015, 10(3): e0119513. doi: 10.1371/journal.pone.0119513
    [13]
    LIU T, LI Z, ZHANG S, et al. Viral etiology of acute respiratory tract infections in hospitalized children and adults in Shangdong Province, China[J]. Virol J, 2015, 12: 168. doi: 10.1186/s12985-015-0388-z
    [14]
    KIMIYA T, SHINJOH M, ANZO M, et al. Effectiveness of inactivated quadrivalent influenza vaccine in the 2015/2016 season as assessed in both a test-negative case-control study design and a traditional case-control study design[J]. Eur J Pediatr, 2018, 177(7): 1009-1017. doi: 10.1007/s00431-018-3145-7
    [15]
    SU W J, CHAN T C, CHUANG P, et al. Estimating influenza vaccine effectiveness using routine surveillance data among children aged 6-59 months for five consecutive influenza seasons[J]. Int J Infect Dis, 2015, 30: 115-121. doi: 10.1016/j.ijid.2014.11.011
    [16]
    SIMPSON M D, KIEKE B A, SUNDARAM M E, et al. Incidence of medically attended respiratory syncytial virus and influenza illnesses in children 6-59 months old during four seasons[J]. Open Forum Infect Dis, 2016, 3(2): 81-86. http://pdfs.semanticscholar.org/73f4/8a992c779f349ff5e305afe2f0538699ec33.pdf
    [17]
    ZHENG J, HUO X, HUAI Y, et al. Epidemiology, seasonality and treatment of hospitalized adults and adolescents with influenza in Jingzhou, China, 2010-2012[J]. PLoS One, 2016, 11(3): e0150713. doi: 10.1371/journal.pone.0150713
    [18]
    HUAI Y, GUAN X, LIU S, et al. Clinical characteristics and factors associated with severe acute respiratory infection and influenza among children in Jingzhou, China[J]. Influenza Other Respir Viruses, 2017, 11(2): 148-156. doi: 10.1111/irv.12419
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