Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1206-1209
SHANG Xin-tong, HUANG Nan, QIU Ya-fen. Effect of Chinese Herbal Decoction combined with dydrogesterone in the treatment of early threatened abortion[J]. Chinese Journal of General Practice, 2021, 19(7): 1206-1209. doi: 10.16766/j.cnki.issn.1674-4152.002022
Citation: SHANG Xin-tong, HUANG Nan, QIU Ya-fen. Effect of Chinese Herbal Decoction combined with dydrogesterone in the treatment of early threatened abortion[J]. Chinese Journal of General Practice, 2021, 19(7): 1206-1209. doi: 10.16766/j.cnki.issn.1674-4152.002022
shu

Effect of Chinese Herbal Decoction combined with dydrogesterone in the treatment of early threatened abortion

doi: 10.16766/j.cnki.issn.1674-4152.002022

  • Department of Obstetrics, Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310000, China

Funds:

 2019KY498

  • Received Date: 2020-09-04
    Available Online: 2022-02-16
    Abstract
  •   Objective  To explore the effect of self-made Gushen Antai Decoction combined with dydrogesterone in the treatment of early threatened abortion in order to provide a reference for the clinical treatment of early threatened abortion.  Methods  Eighty cases of early threatened abortion at the Affiliated Hospital of Hangzhou Normal University from January 2017 to December 2019 were selected and randomly divided into observation group and control group (40 cases in each group). The control group was treated with dydrogesterone, whereas the observation group was treated with Gushen Antai Decoction on the basis of the control group. The clinical efficacy, improvement of clinical indicators, progesterone level, nuchal translucency thickness (NT) and crown hip length (CRL) of foetuses, success rate of foetal preservation and incidence of adverse reactions at 12-14 weeks of gestation were compared between the two groups.  Results  After treatment, the total effective rate and the success rate of foetal preservation in the observation group were 92.5% (37/40), which were significantly higher than those in the control group [75.0% (30/40) and 72.5% (29/40), respectively. P < 0.05]. After treatment, the relief time of waist pain, abdominal pain and haemostasis in the observation group were significantly shorter than those in the control group (all P < 0.05). The levels of β-human chorionic gonadotropin, progesterone and estradiol in the observation group were significantly higher than those in the control group (all P < 0.05). No significant difference was observed in foetal NT and CRL levels and the incidence of adverse reactions between the two groups of patients at 12-14 weeks of gestation (P>0.05).  Conclusion  Gushen Antai Decoction has a significant effect on the treatment of early threatened abortion. It can effectively stabilise the patient's progesterone level, relieve the symptoms of abdominal pain and back pain, increase the efficiency of foetal preservation and is safe and reliable.

     

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