Volume 20 Issue 2
Feb.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(2): 224-227
LIANG Yu-jie, ZHANG Yong-qi, CHEN Meng-jie, GUAN Han, LI Wen-yong, LIU Bei-bei, LIU Jian-min. Predictive value of the pre-operative prognostic nutrition index for the survival of patients undergoing radical prostatectomy[J]. Chinese Journal of General Practice, 2022, 20(2): 224-227. doi: 10.16766/j.cnki.issn.1674-4152.002318
Citation: LIANG Yu-jie, ZHANG Yong-qi, CHEN Meng-jie, GUAN Han, LI Wen-yong, LIU Bei-bei, LIU Jian-min. Predictive value of the pre-operative prognostic nutrition index for the survival of patients undergoing radical prostatectomy[J]. Chinese Journal of General Practice, 2022, 20(2): 224-227. doi: 10.16766/j.cnki.issn.1674-4152.002318
shu

Predictive value of the pre-operative prognostic nutrition index for the survival of patients undergoing radical prostatectomy

doi: 10.16766/j.cnki.issn.1674-4152.002318

  • Department of Urology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 2008085QH358

 BYKY2019035ZD

  • Received Date: 2021-07-23
    Available Online: 2022-03-04
    Abstract
  •   Objective  To explore whether or not the prognostic nutrition index (PNI) can be used to evaluate the prognosis of patients undergoing the radical resection of prostate cancer.  Methods  Retrospective analysis was performed on 156 patients who underwent radical resection of prostate cancer in the First Affiliated Hospital of Bengbu Medical College from January 2014 to January 2015. Clinical data and follow-up data of patients with prostate cancer were determined on the basis of the results of the first blood examination at the time of radical surgery. Pre-operative PNI, neutrophil-to-lymphocyte ratio and lymphatic-to-monocyte ratio were calculated. On the basis of the characteristics of receiver operating characteristic curve, the optimal cut-off value on the curve was intercepted. The overall survival (OS) of patients was analysed by Kaplan-Meier survival curve, and the association between the prognosis of patients undergoing radical surgery and pre-operative PNI was analysed by Cox proportional risk model.  Results  The pre-operative PNI of patients was 49.58±6.69, the best cut-off value was 50.77. The high PNI group (≥ 50.77, 75 patients) had a significantly higher 5-year OS rate than the low PNI group (< 50.77, 81 patients). PNI was an independent risk element for 5-year OS after the radical resection of prostate cancer.  Conclusion  Pre-operative PNI is an independent risk factor affecting the survival of patients with prostate cancer after radical surgery, and it has a certain clinical application value to evaluate the prognosis of patients with prostate cancer undergoing radical surgery.

     

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