Volume 20 Issue 4
Apr.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(4): 691-695
CHEN Jin-ming, ZHANG Fen, DENG Jiao, WANG Wei-bin, CHEN Qi-liang, YU Jie. Correlation between TCM constitution and polycystic ovary syndrome: a meta-analysis[J]. Chinese Journal of General Practice, 2022, 20(4): 691-695. doi: 10.16766/j.cnki.issn.1674-4152.002432
Citation: CHEN Jin-ming, ZHANG Fen, DENG Jiao, WANG Wei-bin, CHEN Qi-liang, YU Jie. Correlation between TCM constitution and polycystic ovary syndrome: a meta-analysis[J]. Chinese Journal of General Practice, 2022, 20(4): 691-695. doi: 10.16766/j.cnki.issn.1674-4152.002432
shu

Correlation between TCM constitution and polycystic ovary syndrome: a meta-analysis

doi: 10.16766/j.cnki.issn.1674-4152.002432
  • 1.

    College of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China

Funds:

 2019J01351

  • Received Date: 2021-04-16
    Available Online: 2022-08-20
    Abstract
  •   Objective  To summarise the research status of traditional Chinese medicine (TCM) constitution types and polycystic ovary syndrome (PCOS), and to explore the distribution of TCM constitution of PCOS patients, so as to provide evidence-based medical evidence for TCM prevention and treatment of PCOS.  Methods  The databases of CNKI, CQVIP, Wanfang Data, PubMed, Cochrane and Embase were searched, and all clinical research documents of TCM constitution types of PCOS were retrieved. Meta-analysis was carried out with Stata 16.0, and the effect values were expressed in terms of rate, ratio and 95% confidence interval.  Results  Twenty studies were included with 4 928 individuals. The results showed that phlegm-dampness, yang deficiency, qi stagnation and qi deficiency accounted for 15.8%, 14.1%, 12.5% and 12.1% of PCOS patients, respectively. Subgroup analysis by region showed that the proportion of phlegm-dampness, yang deficiency and special was the highest in Central China, blood stasis constitutions and qi deficiency were the highest in North China, qi stagnation and damp-heat constitutions were the highest in East China, and balanced constitution and yin deficiency were the highest in South China and West China. The comparison of constitution types between PCOS patients and the general population showed that phlegm dampness (OR=1.871, 95% CI: 1.109-3.156, P=0.019) and peace (OR=0.313, 95% CI: 0.208-0.472, P < 0.001). There was no significant difference in other constitution types.  Conclusion  Phlegm-dampness, yang deficiency, qi stagnation and qi deficiency are the main constitution types of PCOS patients. Phlegm-dampness is a risk factor of PCOS, and balanced constitution is a protective factor of PCOS.

     

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