Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 934-936
LIU Shan-qing, WANG Nan, ZHANG Yan-bei. Application of bedside electronic bronchoscopic alveolar lavage in the treatment of severe pulmonary infection[J]. Chinese Journal of General Practice, 2022, 20(6): 934-936. doi: 10.16766/j.cnki.issn.1674-4152.002491
Citation: LIU Shan-qing, WANG Nan, ZHANG Yan-bei. Application of bedside electronic bronchoscopic alveolar lavage in the treatment of severe pulmonary infection[J]. Chinese Journal of General Practice, 2022, 20(6): 934-936. doi: 10.16766/j.cnki.issn.1674-4152.002491
shu

Application of bedside electronic bronchoscopic alveolar lavage in the treatment of severe pulmonary infection

doi: 10.16766/j.cnki.issn.1674-4152.002491
  • 1.

    Intensive Care Unit, the Fourth Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China

Funds:

 KJ2018A0208

  • Received Date: 2021-12-03
    Available Online: 2022-09-21
    Abstract
  •   Objective  To investigate the effect of electronic bronchoscopic alveolar lavage in the treatment of severe pneumonia.  Methods  Forty patients with severe pulmonary infection complicated with respiratory failure admitted to the Intensive Care Department of the Fourth Affiliated Hospital of Anhui Medical University from December 2018 to January 2021 were selected. They were divided into the observation group and control group according to treatment methods, with 20 patients in each group. The control group was treated with anti-infection, mechanical ventilation, sputum aspiration and other conventional treatments, whereas the observation group was treated with electronic bronchoscopic alveolar lavage on the basis of conventional treatment. The clinical efficacy, blood gas analysis, inflammatory indicators and operation safety of the two groups were observed.  Results  The curative effect of the observation group was higher than that of the control group(Z=2.054, P=0.040). After treatment, the observation group had higher arterial partial pressure of oxygen [(113.88±17.52) mm Hg vs. (91.36±16.70) mm Hg, P < 0.001, 1 mm Hg=0.133 kPa] and oxygenation index [(308.42±55.25) mm Hg vs. (258.43±64.02) mm Hg, P=0.012] and lower arterial partial pressure of carbon dioxide [(34.33±3.92) mm Hg vs. (37.37±2.72) mm Hg, P=0.007] than the control group. The white blood cell count [(7.42±1.82)×109/L], high-sensitivity C-reactive protein [22.43 (11.66, 31.02) mg/L] and procalcitonin [0.32 (0.14, 0.44) ng/mL] in the observation group were lower than those in the control group [(9.66±2.57)×109/L, 44.79 (16.03, 87.01) mg/L and 0.73 (0.17, 2.29)ng/mL, respectively, all P < 0.05]. There were no serious adverse reactions during bronchoalveolar lavage in the observation group.  Conclusion  Bronchoscopic alveolar lavage is safe, can improve lung function and has significant effect on the control of pulmonary infection.

     

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