Volume 20 Issue 8
Aug.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(8): 1319-1322
SUN Shi-bang, ZHU Chun-yan, XIA Yong. Risk factors for suicidal behaviour in patients with depressive episodes of bipolar disorder[J]. Chinese Journal of General Practice, 2022, 20(8): 1319-1322. doi: 10.16766/j.cnki.issn.1674-4152.002586
Citation: SUN Shi-bang, ZHU Chun-yan, XIA Yong. Risk factors for suicidal behaviour in patients with depressive episodes of bipolar disorder[J]. Chinese Journal of General Practice, 2022, 20(8): 1319-1322. doi: 10.16766/j.cnki.issn.1674-4152.002586
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Risk factors for suicidal behaviour in patients with depressive episodes of bipolar disorder

doi: 10.16766/j.cnki.issn.1674-4152.002586

  • Department of Psychiatry, Mental Health Centre Affiliated to Zhejiang University School of Medicine, Hangzhou Seventh People's Hospital, Hangzhou, Zhejiang 310013, China

Funds:

 2021KY914

  • Received Date: 2022-03-08
    Abstract
  •   Objective  Suicide is one of the key factors for high mortality in patients with depressive episodes of bipolar disorder. This study explored the risk factors of suicidal behaviour in patients with depressive episodes of bipolar disorder to reduce the occurrence of suicidal behaviour in such patients.  Methods  Using the method of cross-sectional study, 182 patients with depressive episodes of bipolar disorder who were hospitalised in Hangzhou Seventh People's Hospital from January 2018 to December 2021 were enrolled. They were classified into the suicidal behaviour group (n=80) and non-suicide behaviour group (n=102). The demographic characteristics, clinical features and thyroid function parameters of the two groups were compared. The statistically significant factors were analysed by logistic regression to determine the risk factors of suicidal behaviour in patients with depressive episodes of bipolar disorder.  Results  Compared with the non-suicide behaviour group, the suicidal behaviour group showed decreased age and age of onset, the number of previous suicide attempts, the number of non-suicidal self-injury in the past were higher. The proportion of previous suicide attempts and non-suicidal self-injury in the past was higher. The levels of free triiodothyronine (FT3) and total triiodothyronine (TT3) in peripheral blood were lower (all P < 0.05). Binary logistic regression showed, previous suicide attempt (OR=3.399), and non-suicidal self-injury (OR=4.190) were risk factors for suicidal behaviour in patients with bipolar in patients with major depressive episode of bipolar disorder, older age at first onset (OR=0.874) and higher FT3 (OR=0.153) were protective factors (all P < 0.05).  Conclusion  Previous attempted suicide behavior and previous non-suicidal self-injury behavior were risk factors of suicidal behavior in bipolar depression patients. Older age at first onset and higher FT3 were protective factors, which need to be paid attention to in clinic.

     

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