Volume 20 Issue 9
Sep.  2022
Turn off MathJax
Article Contents
YAN Xing, CHEN Huai-jing, LIU Hui, DUAN Dan, GONG Zhuo. Willingness and influencing factors of HIV pre-exposure prophylaxis for 295 men who have sex with men in Changsha[J]. Chinese Journal of General Practice, 2022, 20(9): 1560-1564. doi: 10.16766/j.cnki.issn.1674-4152.002649
Citation: YAN Xing, CHEN Huai-jing, LIU Hui, DUAN Dan, GONG Zhuo. Willingness and influencing factors of HIV pre-exposure prophylaxis for 295 men who have sex with men in Changsha[J]. Chinese Journal of General Practice, 2022, 20(9): 1560-1564. doi: 10.16766/j.cnki.issn.1674-4152.002649

Willingness and influencing factors of HIV pre-exposure prophylaxis for 295 men who have sex with men in Changsha

doi: 10.16766/j.cnki.issn.1674-4152.002649
Funds:

 20200064

 19C0217

  • Received Date: 2021-12-11
    Available Online: 2022-11-29
  •   Objective  To understand the needs and influencing factors of men who have sex with men (MSM) for HIV pre-exposure prophylaxis (PrEP) in Changsha.  Methods  A cross-sectional study was conducted using the on-site questionnaire survey method in MSM Sentinel of Changsha from January to December 2020. MSM with different characteristics was used to test the difference in PrEP service demand. Single-factor analysis was performed, and an unconditional two-category logistic regression model was used for multivariate analysis.  Results  Approximately 54.20% of MSM had heard of PrEP, and 30.80% expressed their willingness to accept PrEP. The awareness rate was higher than the willingness to use it. Monthly income level (χ2=17.037, P < 0.05), perception of local MSM infection with AIDS (χ2=8.449, P < 0.05), dangerous sexual behaviours such as condom rupture and slippage (χ2=9.916, P < 0.05) and same-sex commercial sex in the last 6 months (χ2=6.717, P < 0.05) were determined. The differences were statistically significant between the PrEP service demand and above factors. MSM with high monthly income, having dangerous sexual behaviours such as condom rupture or slippage, and believing that the local MSM AIDS epidemic was serious were more willing to use prep services, the corresponding OR values were 3.339, 3.710 and 2.517, respectively.  Conclusion  The MSM in Changsha City is dominated by young and highly educated singles. The awareness rate of PrEP services is relatively high, and the willingness to use it is lower than the awareness rate. There is a phenomenon of separation of awareness and action. Monthly income level, perception of local MSM infection with HIV and history of dangerous sexual behaviours such as condom rupture and slippage are related to the demand for PrEP services.

     

  • loading
  • [1]
    莫实德. 中国男男性行为者艾滋病高危行为特征研究进展[J]. 安徽预防医学杂志, 2020, 26(1): 42-45. https://www.cnki.com.cn/Article/CJFDTOTAL-AHYF202001012.htm

    MO S D. Research progress on the characteristics of HIV/AIDS high-risk behaviors among men who have sex with men in China[J]. Anhui Journal of Preventive Medicine, 2020, 26(1): 42-45. https://www.cnki.com.cn/Article/CJFDTOTAL-AHYF202001012.htm
    [2]
    杨人贵, 黄竹林, 欧新华. 长沙市2011-2016年艾滋病流行特征[J]. 中国热带医学, 2018, 18(5): 449-451, 455.

    YANG R G, HUANG Z L, OU X H. Epidemiological characteristics analyzation of HIV/AIDS cases in Changsha, 2011-2016[J]. China Tropical Medicine, 2018, 18(5): 449-451, 455.
    [3]
    MAYER K H, MOLINA J M, THOMPSON M A, et al. Emtricitabine and tenofovir alafenamidevs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): Primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial[J]. Lancet, 2020, 396(10246): 239-254. doi: 10.1016/S0140-6736(20)31065-5
    [4]
    PENG L J, LI P, GILMOUR S, et al. A mathematical model of biomedical interventions for HIV prevention among men who have sex with men in China[J]. BMC Infect Dis, 2018, 18(1): 600. doi: 10.1186/s12879-018-3516-8
    [5]
    中华医学会感染病学分会艾滋病丙型肝炎学组, 中国疾病预防控制中心. 中国艾滋病诊疗指南(2018版)[J]. 中国艾滋病性病, 2018, 24(12): 1266-1282. https://www.cnki.com.cn/Article/CJFDTOTAL-XFCR201902002.htm

    HIV/AIDS Hepatitis C Research Group, Chinese Association of Infectious Diseases, Chinese Center for Disease Control and Prevention. Guidelines for HIV/AIDS Diagnosis and Treatment in China (2018 edition)[J]. Chinese Journal of AIDS & STD, 2018, 24(12): 1266-1282. https://www.cnki.com.cn/Article/CJFDTOTAL-XFCR201902002.htm
    [6]
    肖璨, 付朝智, 马婧, 等. 开远市200名男男性行为者艾滋病暴露前预防用药使用意愿[J]. 中国艾滋病性病, 2019, 25(7): 741-742. https://www.cnki.com.cn/Article/CJFDTOTAL-XBYA201907025.htm

    XIAO C, FU C Z, MA J, et al. Intention to use AIDS pre-exposure prophylaxis among 200 men who have sex with men in Kaiyuan City[J]. Chinese Journal of AIDS & STD, 2019, 25(7): 741-742. https://www.cnki.com.cn/Article/CJFDTOTAL-XBYA201907025.htm
    [7]
    谢棚印, 王夏, 刘普林, 等. 2015年武汉市301名男男性行为人群对HIV暴露前预防用药使用意愿及相关因素[J]. 中华预防医学杂志, 2017, 51(11): 1001-1006. doi: 10.3760/cma.j.issn.0253-9624.2017.11.009

    XIE P Y, WANG X, LIU P L, et al. Willingness and influencing factors of using pre-exposure prophylaxis among 301 men have sex with men in Wuhan city, 2015[J]. Chinese Journal of Preventive Medicine, 2017, 51(11): 1001-1006. doi: 10.3760/cma.j.issn.0253-9624.2017.11.009
    [8]
    石安霞, Don Operario, 张志华, 等. 男男性行为人群HIV暴露前预防需求与使用障碍研究[J]. 中华流行病学杂志, 2020, 41(3): 343-344, 348. doi: 10.3760/cma.j.issn.0254-6450.2020.03.012

    YOU A X, Don Operario, ZHANG Z H, et al. Needs of pre-exposure prophylaxis for HIV infection and related barriers among men who have sex with men[J]. Chinese Journal of Epidemiology, 2020, 41(3): 343-344, 348. doi: 10.3760/cma.j.issn.0254-6450.2020.03.012
    [9]
    肖璨. 云南省两地MSM人群艾滋病暴露前预防用药接受意愿及影响因素研究[D]. 昆明: 昆明医科大学, 2019.

    XIAO C. Study on acceptance willingness and influencing factors of AIDS pre-exposure prophylaxis among MSM population in Yunnan Province[D]. Kunming: Kunming Medical University, 2019.
    [10]
    ZHENG Z W, QIU J L, GU J, et al. Pre-exposure prophylaxis comprehension and the certainty of willingness to use pre-exposure prophylaxis among men who have sex with men in China[J]. Int J STD AIDS, 2019, 30(1): 4-11. doi: 10.1177/0956462418781142
    [11]
    马奇三, 王正平, 李金亮, 等. 抗艾滋病药物的现状与挑战[J]. 聊城大学学报(自然科学版), 2020, 33(1): 70-78. https://www.cnki.com.cn/Article/CJFDTOTAL-TALK202001013.htm

    MA Q S, WANG Z P, LI J L, et al. Anti-aids drugs status quo and challenges[J]. Journal of Liaocheng University (Natural Science Edition), 2020, 33(1): 70-78. https://www.cnki.com.cn/Article/CJFDTOTAL-TALK202001013.htm
    [12]
    吴联朋, 何贵清, 胡型忠, 等. 温州地区51例AIDS合并播散性马尔尼菲篮状菌病患者临床特征及死亡危险因素分析[J]. 中华全科医学, 2021, 19(8): 1398-1402. doi: 10.16766/j.cnki.issn.1674-4152.002070

    WU L P, HE G Q, HU X Z, et al. Analysis of clinical characteristics and risk factors of death in 51 AIDS patients with disseminated Talaromycosis marneffei in Wenzhou[J]. Chinese Journal of General Practice, 2021, 19(8): 1398-1402. doi: 10.16766/j.cnki.issn.1674-4152.002070
    [13]
    黄朝辉, 张悦, 郭刘闰南, 等. HIV感染孕产妇启动抗病毒治疗情况及影响因素分析[J]. 中华全科医学, 2021, 19(6): 954-958. doi: 10.16766/j.cnki.issn.1674-4152.001959

    HUANG C H, ZHANG Y, GUO L R N, et al. Initiation of antiretroviral treatment among HIV-infected pregnant women and associated factors[J]. Chinese Journal of General Practice, 2021, 19(6): 954-958. doi: 10.16766/j.cnki.issn.1674-4152.001959
    [14]
    KESLER M A, KAUL R, MYERS T, et al. Perceived HIV risk, actual sexual HIV risk and willingness to take pre-exposure prophylaxis among men who have sex with men in Toronto, Canada[J]. Aids Care, 2016, 28(11): 1378-1385.
    [15]
    PENG L P, CAO W G, GU J, et al. Willingness to use and adhere to HIV pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in China[J]. Int J Environ Res Public Health, 2019, 16(14): 2620-2623.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Article Metrics

    Article views (282) PDF downloads(3) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return