Study on the rehabilitation effect of <i>Kaiqiao Dingzhi</i> Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke

ZHAO Wen-hua; LU Jun-ying; ZHAO Huai-xiao; LIU Yin-fang; ZHANG Xiao-man

doi:10.16766/j.cnki.issn.1674-4152.002698

Volume 20 Issue 10

Oct. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(10): 1763-1768

ZHAO Wen-hua, LU Jun-ying, ZHAO Huai-xiao, LIU Yin-fang, ZHANG Xiao-man. Study on the rehabilitation effect of Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke[J]. Chinese Journal of General Practice, 2022, 20(10): 1763-1768. doi: 10.16766/j.cnki.issn.1674-4152.002698

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ZHAO Wen-hua, LU Jun-ying, ZHAO Huai-xiao, LIU Yin-fang, ZHANG Xiao-man. Study on the rehabilitation effect of Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke[J]. Chinese Journal of General Practice, 2022, 20(10): 1763-1768. doi: 10.16766/j.cnki.issn.1674-4152.002698

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Study on the rehabilitation effect of Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke

doi: 10.16766/j.cnki.issn.1674-4152.002698

1.
Internal Medicine Department, Staff Hospital of Henan Wujian Construction Group, Zhengzhou, Henan 450000, China

Funds:

2018020725

Received Date: 2022-03-21
Available Online: 2022-11-30

Abstract

Abstract

Objective To observe the effect of rehabilitation intervention using Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on patients with unilateral spatial neglect after stroke. Methods A total of 94 patients suffering from stroke and unilateral spatial neglect and admitted to the Staff Hospital of Henan Wujian Construction Group from January 2019 to June 2020 were divided into treatment group (47 cases) and control group (47 cases) by the random-number table method. The patients in the control group underwent visual observation training on the basis of routine rehabilitation training, whereas the patients in the observation group received a combination of Kaiqiao Dingzhi Prescription and head acupuncture. The indicators of the two groups were compared. Results Compared with the control group, the scores of linear bisection test, bell drawing test, copy drawing test and number deletion test in the observation group all decreased after treatment (all P < 0.05). The Fugl-Meyer motor function assessment (FMA), activities of daily living (ADL) and stroke specific quality of life scale (SS-QOL) scores of the observation group significantly increased (all P < 0.05). After 2 and 4 weeks of treatment, the Catherine Bergego scale (CBS) score of the observation group was significantly lower than that of the control group [(16.17±2.32) points vs. (18.24±3.27) points, (12.58±1.83) points vs. (16.06±2.10) points, all P < 0.05]. The mini-mental state examination (MMSE) score of cognitive function was significantly higher than that of the control group [(24.16±3.25) points vs. (22.30±3.20) points, (26.51±2.78) points vs. (25.10±1.69) points, all P < 0.05]. After treatment, the serum S100β, macrophage inflammatory protein-1α (MIP-1α), neuron-specific enolase (NSE) levels, platelet aggregation rate, fibrinogen, whole blood high shear viscosity and whole blood low shear viscosity of the observation group were significantly lower than that of the control group (all P < 0.05). Conclusion Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training are beneficial to control unilateral spatial neglect of patients after stroke, which may be related to the inhibited expression of S100β, MIP-1α and NSE, improving hemorheology to promote brain function recovery and improve cerebral blood perfusion.
- Kaiqiao Dingzhi Prescription,
- Head needle,
- Visual observation training,
- Unilateral spatial neglect after stroke,
- Clinical research

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References(25)

References

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Study on the rehabilitation effect of Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke

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Study on the rehabilitation effect of Kaiqiao Dingzhi Prescription and head acupuncture combined with visual observation training on unilateral spatial neglect after stroke

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