Volume 20 Issue 12
Dec.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(12): 2092-2095
YU Hai-jing, LI Yang, GUO Yan, DU Yan-wei, DUAN Yuan-yuan. Research on quantitative or semi-quantitative assessment of placental function in pationts with hypertension of pregnancy by dual-mode ultrasound[J]. Chinese Journal of General Practice, 2022, 20(12): 2092-2095. doi: 10.16766/j.cnki.issn.1674-4152.002777
Citation: YU Hai-jing, LI Yang, GUO Yan, DU Yan-wei, DUAN Yuan-yuan. Research on quantitative or semi-quantitative assessment of placental function in pationts with hypertension of pregnancy by dual-mode ultrasound[J]. Chinese Journal of General Practice, 2022, 20(12): 2092-2095. doi: 10.16766/j.cnki.issn.1674-4152.002777
shu

Research on quantitative or semi-quantitative assessment of placental function in pationts with hypertension of pregnancy by dual-mode ultrasound

doi: 10.16766/j.cnki.issn.1674-4152.002777
  • 1.

    Ultrasound Department of Suzhou Hospital Affiliated to Anhui Medical University (Suzhou Municipal Hospital, Anhui Province), Suzhou, Anhui 234000, China

Funds:

 KJ2018A1003

  • Received Date: 2022-04-26
    Available Online: 2023-02-07
    Abstract
  •   Objective  To explore the value of dual-modal ultrasound in quantitative or semi-quantitative evaluation of placental function in patients with hypertension of pregnancy.  Methods  A total of 163 pregnant women admitted to Suzhou Municipal Hospital from January 2018 to June 2021 were selected, and their gestational weeks were 30-41 weeks. Among them, 103 were patients with hypertension in pregnancy (38 cases of severe preeclampsia, 65 cases of preeclampsia), and 60 were normal pregnant women. The placental blood flow filling was monitored by three-dimensional power Doppler ultrasound, and placental energy histograms (VI, FI, VFI) were obtained. The fetal umbilical artery, middle cerebral artery, maternal uterine artery spectrum (PI, RI, S/D) were monitored by spectral Doppler ultrasound.  Results  With the disease progresses, three-dimensional power placental blood flow filling histogram data (VI, FI, VFI) of patients with hypertension of pregnancy decreased (P < 0.05), the fetal umbilical artery blood flow spectrum (PI, RI, S/D) increased (P < 0.05), the fetal middle cerebral artery blood flow spectrum (PI, RI, S/D) decreased (P < 0.05), and the pregnant women' s uterine artery blood flow spectrum (PI, RI, S/D) increased (P < 0.05). The ROC curve analysis found that monitor fetal umbilical artery S/D, middle cerebral artery PI, maternal uterine artery spectrum PI and energy histograms VFI had high diagnostic value for severe preeclampsia/preeclampsia (AUC=0.893, 0.827, 0.912, 0.880, all P < 0.05), and the diagnostic value of combined detection of the four was the highest (AUC=0.957, P < 0.05). After 30 weeks of gestation, when umbilical artery S/D was higher than 3.010, middle cerebral artery PI was lower than 1.575, uterine artery PI was higher than 1.215, placental VFI was lower than 4.755, there was a high sensitivity and specificity in the diagnosis of impaired placental function in gestational hypertension.  Conclusion  Dual-modal ultrasound imaging can quantitatively or semi-quantitatively analyze the changes of placental blood perfusion, and provide guidance for clinical evaluation of placental function in patients with hypertension of pregnancy.

     

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