Analysis of the clinical characteristics and hospitalization costs of IgG4-related diseases

LYU Zhijie; WU Li; ZHANG Hongxia; DU Ping

doi:10.16766/j.cnki.issn.1674-4152.003048

Volume 21 Issue 6

Jun. 2023

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Article Navigation > Chinese Journal of General Practice > 2023 > 21(6): 1056-1059

LYU Zhijie, WU Li, ZHANG Hongxia, DU Ping. Analysis of the clinical characteristics and hospitalization costs of IgG4-related diseases[J]. Chinese Journal of General Practice, 2023, 21(6): 1056-1059. doi: 10.16766/j.cnki.issn.1674-4152.003048

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LYU Zhijie, WU Li, ZHANG Hongxia, DU Ping. Analysis of the clinical characteristics and hospitalization costs of IgG4-related diseases[J]. Chinese Journal of General Practice, 2023, 21(6): 1056-1059. doi: 10.16766/j.cnki.issn.1674-4152.003048

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Analysis of the clinical characteristics and hospitalization costs of IgG4-related diseases

doi: 10.16766/j.cnki.issn.1674-4152.003048

LYU Zhijie¹
, WU Li²
, ZHANG Hongxia³
, DU Ping^{4
,
,}

1.
Clinical Pharmacy Office, Qiantang Campus, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China

Funds:

2022KY833

A20210514

Received Date: 2022-03-12
Available Online: 2023-08-26

Abstract

Abstract

Objective To analyze the clinical characteristics and hospitalization costs of 42 IgG4-related diseases (IgG4-RD) patients, so as to provide reference for improving early diagnosis and reasonable cost control. Methods Clinical data of 42 IgG4-RD patients admitted to Sir Run Run Shaw Hospital Zhejiang University School of Medicine from October 2016 to October 2021 were retrospectively collected for statistical analysis. Results Among the 42 patients, the number of involved organ was 1 to 5, and the most common organs were pancreas (42.86%), biliary (26.19%), lymphatic (30.95%), the interquartile range of IgG4-RD responder index was 5.5(3.0, 7.0) and the number of involved organ was positively associated with serum of IgG4 and IgG4-RD responder index (IgG4-RD RI). There were 28 patients treated with glucocorticoids alone, 10 patients treated with glucocorticoids combined with immunosuppressant, 2 patients were not given drug treatment, 2 patients refused glucocorticoids treatment, 33 patients responded well to drug treatment, and serum of IgG4, erythrocyte sedimentation rate (ESR) and IgG4-RD RI decreased compared with previous treatment. The median hospitalization cost of IgG4-RD patients was 13 808.15 (6 968.50, 24 652.09) yuan. Drug treatment factors, surgical material factors, and co-examination factors were the three public factors affecting the hospitalization cost of patients with IgG4-RD. Conclusion IgG4-RD is a group of systemic diseases that occurs well in middle-aged and elderly men, with multiple organ involved and is highly treatable. Serum of IgG4 and IgG4-RD RI can be used as important reference indicators for clinical diagnosis and therapeutic evaluation. The hospitalization costs of IgG4-RD patients can be reasonably controlled from western medicine costs, surgical materials costs and examination costs.
- IgG4-related diseases,
- Serum of IgG4,
- Involved organs,
- Diagnosis,
- Treatment,
- Hospitalization costs

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References

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Analysis of the clinical characteristics and hospitalization costs of IgG4-related diseases

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