Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1566-1570
PAN Qi, REN Jingjing. Research progress in treatment of perimenopausal vasomotor symptoms[J]. Chinese Journal of General Practice, 2023, 21(9): 1566-1570. doi: 10.16766/j.cnki.issn.1674-4152.003172
Citation: PAN Qi, REN Jingjing. Research progress in treatment of perimenopausal vasomotor symptoms[J]. Chinese Journal of General Practice, 2023, 21(9): 1566-1570. doi: 10.16766/j.cnki.issn.1674-4152.003172
shu

Research progress in treatment of perimenopausal vasomotor symptoms

doi: 10.16766/j.cnki.issn.1674-4152.003172

  • Department of General Practice, the First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang 310003, China

Funds:

 72274169

  • Received Date: 2023-04-03
    Available Online: 2023-10-19
    Abstract
  • Perimenopausal period refers to a period before and after menopause in women, and it's also a period of gradual decline of ovarian function. This stage due to estrogen levels decreased, may appear a series of menopausal symptoms, short lasting 1-2 years, long lasting 10-20 years. Among them, hot flashes and sweating are the prominent manifestation of vasomotor symptoms and the main reason for perimenopausal women to come to see a doctor, which seriously affects women's sleep, work and life. Therefore, how to alleviate perimenopausal vasomotor symptoms has become a hot topic for medical researchers. At present, postmenopausal hormone replacement therapy is still recognized as the primary treatment for women with moderate to severe tidal fever. Hormone replacement therapy has strict indications and contraindications. Long-term use requires regular and comprehensive physical examination to assess the benefit/risk ratio to ensure medication safety. But there are still some risks in cardiovascular disease, venous thrombosis, endometrial cancer, breast cancer and other hormone-dependent tumors, the acceptance of hormone replacement therapy is not high. In recent years, more and more research has been conducted on the treatment of vasodilatory symptoms. Non-hormonal medications such as selective 5-hydroxytryptamine reuptake inhibitors (SSRI)/selective 5-hydroxytryptamine and norepinephrine dual reuptake inhibitors (SNRI), black cohosh extract, and kuntai capsules, as well as non-pharmacological treatments such as mind-body therapies, and acupuncture treatments, have also provided more treatment choices for women who are deeply afflicted by vasodilatory symptoms. This paper summarizes the treatment measures of vasomotor symptoms in perimenopausal women, including hormone drug therapy, non-hormone drug therapy and non-drug therapy, and provides theoretical guidance for formulating individualized clinical treatment programs to improve the quality of life of perimenopausal women.

     

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