Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1596-1600
ZHANG Qianru, ZHU Jirong, ZHU Mei, GE Jianjun, LI Baozhu. Time series study on the effect of air pollutants on hospitalization risk of arrhythmia patients in Hefei[J]. Chinese Journal of General Practice, 2023, 21(9): 1596-1600. doi: 10.16766/j.cnki.issn.1674-4152.003179
Citation: ZHANG Qianru, ZHU Jirong, ZHU Mei, GE Jianjun, LI Baozhu. Time series study on the effect of air pollutants on hospitalization risk of arrhythmia patients in Hefei[J]. Chinese Journal of General Practice, 2023, 21(9): 1596-1600. doi: 10.16766/j.cnki.issn.1674-4152.003179
shu

Time series study on the effect of air pollutants on hospitalization risk of arrhythmia patients in Hefei

doi: 10.16766/j.cnki.issn.1674-4152.003179
  • 1.

    Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China

Funds:

 81803310

 2021zhyx-C21

 2008085MH240

  • Received Date: 2022-09-19
    Available Online: 2023-10-19
    Abstract
  •   Objective  To investigate the effect of air pollutant exposure on the daily hospitalization number of cardiac arrhythmias in Hefei, and to provide a scientific basis for the development of appropriate intervention measures.  Methods  Meteorological data such as daily average temperature, daily average humidity, air pollutants (PM2.5, PM10, NO2, SO2, CO, O3) and the number of hospitalizations of patients with cardiac arrhythmias were collected in Hefei city from 2015 to 2020. A time-series distributed lag nonlinear model was used to analyze the cumulative and lag effects of air pollutants on the number of hospital cases and hospitalizations in Hefei from 2015 to 2020, and subgroup analysis was performed.  Results  After controlling for long-term trends and confounding factors, this study showed that PM2.5, PM10, NO2 and CO had a significant effect on the number of hospitalizations for arrhythmia onset. In the subgroup, PM2.5, PM10 and CO had an effect on the number of female patients and patients aged <65 years, and all had a lag effects. NO2 had an effect on the number of male inpatients with a lag effect. Every increase of PM10 concentration by 10 μg/m3 had a statistically significant difference in the number of hospitalized patients with arrhythmia on the same day, and the effect value was the largest(RR=1.021, 95% CI: 1.004-1.038). When PM2.5 concentration increased by 10 μg/m3, there was a statistically significant difference in the number of hospitalized patients with arrhythmia on the first day, and the cumulative effect value reached the largest(RR=1.025, 95% CI: 1.011-1.041). When NO2 and CO concentrations increased by 10 μg/m3, the effects on the number of hospitalized patients with arrhythmia accumulated to the second day, and the cumulative effect value reached the largest(RR=1.111, 95% CI: 1.010-1.223; RR=1.248, 95% CI: 1.065-1.462). The effects of SO2 and O3 on the number of hospitalized patients with arrhythmia were not statistically significant (all P>0.05).  Conclusion  The increased concentrations of air pollutants (PM2.5, PM10, NO2, CO) in Hefei can lead to an increased risk of hospitalization for the development of cardiac arrhythmias in the population.

     

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