Volume 21 Issue 11
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YANG Changlin, CAO Shufeng, QIAO Lian, ZHAO Huimin. A case of type Ⅰ Kounis syndrome caused by drug allergy[J]. Chinese Journal of General Practice, 2023, 21(11): 1987-1989. doi: 10.16766/j.cnki.issn.1674-4152.003273
Citation: YANG Changlin, CAO Shufeng, QIAO Lian, ZHAO Huimin. A case of type Ⅰ Kounis syndrome caused by drug allergy[J]. Chinese Journal of General Practice, 2023, 21(11): 1987-1989. doi: 10.16766/j.cnki.issn.1674-4152.003273
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A case of type Ⅰ Kounis syndrome caused by drug allergy

doi: 10.16766/j.cnki.issn.1674-4152.003273

  • Department of General Practice, 970 Hospital of the PLA JLSF, Yantai, Shandong 264000, China

  • Received Date: 2023-02-09
    Available Online: 2024-01-13
    Abstract
  • Kounis syndrome is a syndrome of coronary artery spasm and even acute myocardial infarction secondary to anaphylaxis. The elderly patient in this case developed delayed anaphylaxis when using piperacillin sodium and tazobactam sodium for anti-infective treatment of community-acquired pneumonia in hospital, and the antiallergic treatment improved, but the symptoms of chest tightness and breathlessness occurred, the typical arched back of the inferior wall lead is elevated and dynamic on the electrocardiograph, and the myocardial enzyme is normal. Coronary angiography is performed immediately in the catheter room, which shows a spasm of the right coronary artery, and the spasm disappears after local injection of nitroglycerine. This case is type Ⅰ Kounis syndrome. Kounis syndrome is rare in clinical practice, which can easily lead to missed diagnosis and misdiagnosis. Early recognition and appropriate treatment is the key to improving the clinical prognosis.

     

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