Volume 22 Issue 4
Apr.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(4): 638-641
ZENG Ge, JIANG Junjie, SUN Xing, CONG Huiqin, LI Qiaofeng. Consistency analysis of micro-flow imaging and contrast-enhanced ultrasound in evaluating the condition and synovial blood flow of patients with rheumatoid arthritis[J]. Chinese Journal of General Practice, 2024, 22(4): 638-641. doi: 10.16766/j.cnki.issn.1674-4152.003469
Citation: ZENG Ge, JIANG Junjie, SUN Xing, CONG Huiqin, LI Qiaofeng. Consistency analysis of micro-flow imaging and contrast-enhanced ultrasound in evaluating the condition and synovial blood flow of patients with rheumatoid arthritis[J]. Chinese Journal of General Practice, 2024, 22(4): 638-641. doi: 10.16766/j.cnki.issn.1674-4152.003469
shu

Consistency analysis of micro-flow imaging and contrast-enhanced ultrasound in evaluating the condition and synovial blood flow of patients with rheumatoid arthritis

doi: 10.16766/j.cnki.issn.1674-4152.003469

  • Department of Special Inspection Department, Huzhou Third Municipal Hospital, Huzhou, Zhejiang 313000, China

Funds:

 2021KY1098

  • Received Date: 2023-11-19
    Available Online: 2024-05-29
    Abstract
  •   Objective  To detect synovial blood flow by micro-flow imaging and contrast-enhanced ultrasound, and analyze the consistency of the two imaging methods in evaluating the condition of patients with rheumatoid arthriti.  Methods  A total of 50 patients with active rheumatoid arthritis who were treated in Huzhou Third Municipal Hospital from July 2019 to October 2022 were selected as the research objects. All patients were examined by micro-flow imaging and contrast-enhanced ultrasound, and the synovial blood flow of patients was recorded. After 6 months of treatment, the synovial blood flow of patients was evaluated by micro-flow imaging and contrast-enhanced ultrasound again, and the correlation between the results and laboratory indexes was analyzed by Spearman.  Results  Before treatment, the detection rate of blood flow signals in active patients (Kappa=0.730, P < 0.05) and synovial blood flow evaluation (Kappa=0.797, P < 0.05) were strongly consistent with each other in the micro-flow imaging and contrast-enhanced ultrasound. After 6 months ' treatment, the detection rate of blood flow signals (Kappa=0.845, P < 0.05) and synovial blood flow evaluation (Kappa=0.741, P < 0.05) of patients in remission were both consistent in the micro-flow imaging and contrast-enhanced ultrasound. Micro-flow imaging and contrast-enhanced ultrasound were positively correlated with erythrocyte sedimentation rate, CRP and rheumatoid factor levels in both active and remission stages (P < 0.05), and the correlation of micro-flow imaging was stronger than that of contrast-enhanced ultrasound.  Conclusion  Micro-flow imaging and contrast-enhanced ultrasound have strong consistency in the assessment of synovial blood flow in patients with rheumatoid arthritis in active stage and remission stage, and both have clinical guiding significance for disease assessment.

     

    • FullText(HTML)
  • loading
    • References(22)
  • [1]
    LIN Y J, ANZAGHE M, SCHüLKE S. Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis[J]. Cells, 2020, 9(4): 880. doi: 10.3390/cells9040880
    [2]
    JANG S, KWON E J, LEE J J. Rheumatoid arthritis: pathogenic roles of diverse immune cells[J]. Int J Mol Sci, 2022, 23(2): 905. doi: 10.3390/ijms23020905
    [3]
    CUSH J J. Rheumatoid arthritis: early diagnosis and treatment[J]. Med Clin North Am, 2021, 105(2): 355-365. doi: 10.1016/j.mcna.2020.10.006
    [4]
    CUSH J J. Rheumatoid arthritis: early diagnosis and treatment[J]. Rheum Dis Clin North Am, 2022, 48(2): 537-547. doi: 10.1016/j.rdc.2022.02.010
    [5]
    邵克忠, 陈利民, 李素蘋, 等. 超声造影在类风湿关节炎腕关节炎活动期病变中的诊断价值[J]. 中华全科医学, 2018, 16(6): 980-982, 1035. doi: 10.16766/j.cnki.issn.1674-4152.000269

    SHAO K Z, CHEN L M, LI S P, et al. Value of contrast-enhanced ultrasonography in the diagnosis of rheumatoid arthritis wrist[J]. Chinese Journal of General Practice, 2018, 16(6): 980-982, 1035. doi: 10.16766/j.cnki.issn.1674-4152.000269
    [6]
    LIU H, HUANG C, CHEN S, et al. Value of contrast-enhanced ultrasound for detection of synovial vascularity in experimental rheumatoid arthritis: an exploratory study[J]. J Int Med Res, 2019, 47(11): 5740-5751. doi: 10.1177/0300060519874159
    [7]
    SESKUTE G, JASIONYTE G, RUGIENE R, et al. The Use of superb microvascular imaging in evaluating rheumatic diseases: a systematic review[J]. Medicina (Kaunas), 2023, 59(9): 1641. doi: 10.3390/medicina59091641
    [8]
    LIN M, WANG C. Superb microvascular imaging evaluating joint lesion scores in rheumatoid arthritis compared with power Doppler imaging: a meta-analysis[J]. Medicine (Baltimore), 2020, 99(37): e22185. DOI: 10.1097/MD.0000000000022185.
    [9]
    SUN X, DENG X, XIE W, et al. The agreement between ultrasound-determined joint inflammation and clinical signs in patients with rheumatoid arthritis[J]. Arthritis Res Ther, 2019, 21(1): 100. doi: 10.1186/s13075-019-1892-0
    [10]
    中华医学会风湿病学分会. 2018中国类风湿关节炎诊疗指南[J]. 中华内科杂志, 2018, 57(4): 242-251. doi: 10.3760/cma.j.issn.0578-1426.2018.04.004

    Rheumatology Branch of Chinese Medical Association. 2018 Chinese guideline for the diagnosis and treatment of rheumatoid arthritis[J]. Chinese Journal of Internal Medicine, 2018, 57(4): 242-251. doi: 10.3760/cma.j.issn.0578-1426.2018.04.004
    [11]
    FELSON D T, SMOLEN J S, WELLS G, et al. American College of Rheumatology/European League against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials[J]. Ann Rheum Dis, 2011, 70(3): 404-413. doi: 10.1136/ard.2011.149765
    [12]
    WANG J, WU Z, WANG M, et al. Evaluation of tenosynovitis in patients with seronegative rheumatoid arthritis using microvascular flow imaging[J]. Med Eng Phys, 2022, 110: 103839. DOI: 10.1016/j.medengphy.2022.103839.
    [13]
    GUO D, LIN C, LU Y, et al. FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritis[J]. Bone Res, 2022, 10(1): 45. doi: 10.1038/s41413-022-00211-2
    [14]
    ALIVERNINI S, FIRESTEIN G S, MCINNES I B. The pathogenesis of rheumatoid arthritis[J]. Immunity, 2022, 55(12): 2255-2270. doi: 10.1016/j.immuni.2022.11.009
    [15]
    FILIPPUCCI E, CIPOLLETTA E, MASHADI MIRZA R, et al. Ultrasound imaging in rheumatoid arthritis[J]. Radiol Med, 2019, 124(11): 1087-1100. doi: 10.1007/s11547-019-01002-2
    [16]
    GASSERT F T, GASSERT F G, TOPPING G J, et al. SNR analysis of contrast-enhanced MR imaging for early detection of rheumatoid arthritis[J]. PLoS One, 2019, 14(3): e0213082. DOI: 10.1371/journal.pone.0213082
    [17]
    周丽, 何志容, 刘茂, 等. 超声造影在类风湿关节炎病情判断及治疗效果评估中的应用[J]. 临床误诊误治, 2022, 35(3): 69-72. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWZ202203016.htm

    ZHOU L, HE Z R, LIU M, et al. Contrast-enhanced Ultrasound in Application of Judgment for Rheumatoid Arthritis and Evaluation of Therapeutic Efficacy[J]. Clinical Misdiagnosis & Mistherapy, 2022, 35(3): 69-72. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWZ202203016.htm
    [18]
    YU X, LI Z, REN M, et al. Superb microvascular imaging (SMI) for evaluating hand joint lesions in patients with rheumatoid arthritis in clinical remission[J]. Rheumatol Int, 2018, 38(10): 1885-1890. doi: 10.1007/s00296-018-4112-3
    [19]
    DIAO X H, SHEN Y, CHEN L, et al. Superb microvascular imaging is as sensitive as contrast-enhanced ultrasound for detecting synovial vascularity in rheumatoid arthritis[J]. Quant Imaging Med Surg, 2022, 12(5): 2866-2876. doi: 10.21037/qims-21-859
    [20]
    邱跃文, 金林原, 张艳芬, 等. 彩色超微血管成像在类风湿关节炎治疗中的应用价值[J]. 临床超声医学杂志, 2021, 23(7): 556-559. doi: 10.3969/j.issn.1008-6978.2021.07.025

    QIU Y W, JIN L Y, ZHANG Y F, et al. Application value of color superb microvascular imaging in the treatment of rheumatoid arthritis[J]. Journal of Clinical Ultrasound in Medicine, 2021, 23(7): 556-559. doi: 10.3969/j.issn.1008-6978.2021.07.025
    [21]
    邓雪蓉, 孙晓莹, 张卓莉. 类风湿关节炎患者足踝部体征和超声下病变的一致性[J]. 北京大学学报(医学版), 2021, 53(6): 1037-1042. https://www.cnki.com.cn/Article/CJFDTOTAL-BYDB202106005.htm

    DENG X R, SUN X Y, ZHANG Z L. Agreement between ultrasound-detected inflammation and clinical signs in ankles and feet joints in patients with rheumatoid arthritis[J]. Journal of Peking University: Health Sciences, 2021, 53(6): 1037-1042. https://www.cnki.com.cn/Article/CJFDTOTAL-BYDB202106005.htm
    [22]
    TANG H, QU X, YUE B. Diagnostic test accuracy of magnetic resonance imaging and ultrasound for detecting bone erosion in patients with rheumatoid arthritis[J]. Clin Rheumatol, 2020, 39(4): 1283-1293. doi: 10.1007/s10067-019-04825-6
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (128) PDF downloads(3) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return