Volume 22 Issue 8
Aug.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(8): 1347-1349
ZHENG Jifeng, FENG Caiqin. The correlation between the degree of depression and polysomnography parameters and fatigue level in patients with late-onset depression[J]. Chinese Journal of General Practice, 2024, 22(8): 1347-1349. doi: 10.16766/j.cnki.issn.1674-4152.003633
Citation: ZHENG Jifeng, FENG Caiqin. The correlation between the degree of depression and polysomnography parameters and fatigue level in patients with late-onset depression[J]. Chinese Journal of General Practice, 2024, 22(8): 1347-1349. doi: 10.16766/j.cnki.issn.1674-4152.003633
shu

The correlation between the degree of depression and polysomnography parameters and fatigue level in patients with late-onset depression

doi: 10.16766/j.cnki.issn.1674-4152.003633

  • Department of Psychosomatic Disorders (Second Ward of Sleep), Shaoxing Seventh People ' s Hospital, Shaoxing, Zhejiang 312000, China

Funds:

 2023RC292

  • Received Date: 2024-02-18
    Available Online: 2024-11-19
    Abstract
  •   Objective  The differences in polysomnography parameters and fatigue levels were compared between patients with late-onset depression and non-depressed elderly patients, and the correlation between the degree of depression and sleep quality, structure and fatigue level in patients with late-onset depression was further evaluated.  Methods  A total of 52 patients with late-onset depression admitted to Shaoxing Seventh People ' s Hospital from March 2020 to March 2023 were selected as the study group, and 67 elderly patients without depression during the same period were selected as the control group. The levels of polysomnography parameters and fatigue were compared between groups. Additionally, the correlation between the degree of depression and polysomnography parameters as well as fatigue level in patients with late-onset depression was evaluated.  Results  The sleep efficiency (SE), percentage of N2 phase (N2%) and percentage of slow wave sleep (SWS%) in the study group were lower than those in the control group (P < 0.05). The Pittsburgh sleep quality index (PSQI), sleep latency (SL), micro-arousal index (MAI), fatigue severity scale (FSS), percentage of N1 phase (N1%), percentage of rapid eye movement sleep (REM%), activity, intensity and density of rapid eye movement sleep (REM) in the study group were higher than those in the control group (P < 0.05). Correlation analysis showed that SE and N2% were negatively correlated with the degree of depression in patients, rs=-0.869 and -0.734, respectively. Other indicators were positively correlated with the degree of depression in patients, which were PQSI score (rs=0.786), SL (rs=0.649), AMI (rs=0.714), FSS score (rs=0.738), N1% (rs=0.687), SWS% (rs=0.608), REM% (rs=0.708), REM activity (rs=0.815), REM intensity (rs=0.837) and REM density (rs=0.707).  Conclusion  The sleep quality of patients with late-onset depression is decreased, accompanied by disrupted sleep structure and aggravated fatigue, exhibiting a linear correlation with the degree of depression.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    孔令明, 牛威, 朱晓丽, 等. 老年人晚发性抑郁症预后与外周血lncRNA表达水平和应对方式的关系[J]. 中华老年医学杂志, 2023, 42(3): 267-271.

    KONG L M, NIU W, ZHU X L, et al. Relationship between the prognosis of late-onset depression in the elderly and lncRNA expression levels in peripheral blood and coping styles[J]. Chinese Journal of Geriatrics, 2023, 42(3): 267-271.
    [2]
    美国精神医学学会. 精神障碍诊断与统计手册(第五版)[M]. 北京: 北京大学出版社, 2014.

    American Psychiatric Association. The Diagnostic and Statistical Manual of Mental Disorders-5[M]. Beijing: Peking University Press, 2014.
    [3]
    成俊英. 黛力新治疗围绝经期妇女焦虑伴抑郁症的临床疗效及对医院焦虑/抑郁情绪测定量表和汉密尔顿-抑郁量表评分的影响[J]. 中国妇幼保健, 2023, 38(13): 2486-2490.

    CHENG J Y. The clinical efficacy of Deanxit in the treatment of anxiety and depression in perimenopausal women and its effect on the scores of hospital anxiety/depression scale and Hamilton depression scale[J]. Maternal and Child Health Care of China, 2023, 38(13): 2486-2490.
    [4]
    周翠, 江文, 姚梦, 等. 抑郁焦虑与老年人睡眠质量的关联分析[J]. 中华老年医学杂志, 2023, 42(2): 206-210.

    ZHOU C, JIANG W, YAO M, et al. Relationship between depression and anxiety with sleep quality in elderly adults[J]. Chinese Journal of Geriatrics, 2023, 42(2): 206-210.
    [5]
    夏宁, 聂秀红, 张丽, 等. OSA患者睡眠效率与糖尿病发病率的相关性研究[J]. 中国病案, 2023, 24(5): 103-106.

    XIA N, NIE X H, ZHANG L, et al. Study on the correlation between sleep efficiency and the incidence of diabetes mellitus in OSA patients[J]. Chinese Medical Record, 2023, 24(5): 103-106.
    [6]
    陈超, 常丽, 郭文卉, 等. 多导睡眠呼吸监测中部分脑电相关数据监测在儿科临床应用探讨[J]. 中国医刊, 2022, 57(12): 1367-1369.

    CHEN C, CHANG L, GUO W H, et al. The clinical application of some EEG related data monitoring in polysomnography in pediatrics[J]. Chinese Journal of Medicine, 2022, 57(12): 1367-1369.
    [7]
    刘奕罕, 朱宁, 薛孟周, 等. 阻塞性睡眠呼吸暂停低通气综合征伴脑卒中患者睡眠状况对情绪及日间疲劳的影响[J]. 实用临床医药杂志, 2023, 27(17): 77-81.

    LIU Y H, ZHU N, XUE M Z, et al. Effect of sleep status on mood and daytime fatigue in patients with obstructive sleep apnea hypopnea syndrome complicating with stroke[J]. Journal of Clinical Medicine in Practice, 2023, 27(17): 77-81.
    [8]
    郑鑫, 安建雄. 慢性失眠新学说: 全神经损伤[J]. 中华麻醉学杂志, 2023, 43(11): 1287-1291.

    ZHENG X, AN J X. A new theory of chronic insomnia: comprehensive neural insult[J]. Chinese Journal of Anesthesiology, 2023, 43(11): 1287-1291.
    [9]
    范雪菲, 马亚荣, 邱允, 等. 抑郁症患者睡眠结构与自杀风险的相关性分析[J]. 国际精神病学杂志, 2023, 50(4): 719-722.

    FAN X F, MA Y R, QIU Y, et al. Relationship between sleep structure and suicide risk in patients with depression[J]. Journal of International Psychiatry, 2023, 50(4): 719-722.
    [10]
    颜蓉, 潘友让. 睡眠结构、通气氧合水平与阻塞性睡眠呼吸暂停合并亚临床抑郁症患者人际反应、快感及认知的关系[J]. 中华全科医学, 2023, 21(10): 1643-1646, 1777. doi: 10.16766/j.cnki.issn.1674-4152.003189

    YAN R, PAN Y R. Relationship between sleep structure, ventilation oxygenation level and interpersonal response, pleasure and cognition in patients with obstructive sleep apnea complicated with subclinical depression[J]. Chinese Journal of General Practice, 2023, 21(10): 1643-1646, 1777. doi: 10.16766/j.cnki.issn.1674-4152.003189
    [11]
    郑玉玲, 欧海燕, 熊灿标, 等. 老年失眠患者睡眠结构分析及其影响因素[J]. 中国当代医药, 2021, 28(20): 66-68.

    ZHENG Y L, OU H Y, XIONG C B, et al. Analysis of sleep structure and its influencing factors in elderly patients with insomnia[J]. China Modern Medicine, 2021, 28(20): 66-68.
    [12]
    胡依, 李贝. 基于CHARLS面板数据的中国老年人抑郁症状变动情况及影响因素分析[J]. 中国全科医学, 2021, 24(26): 3281-3287.

    HU Y, LI B. Temporal trend of prevalence of depressive symptoms and associated factors among chinese older adults: an analysis based on the CHARLS panel data[J]. Chinese General Practice, 2021, 24(26): 3281-3287.
    [13]
    叶刚, 李哲, 潘雯, 等. 伴中重度阻塞性睡眠呼吸暂停低通气综合征的抑郁症患者多导睡眠监测特点[J]. 四川精神卫生, 2021, 34(5): 424-428.

    YE G, LI Z, PAN W, et al. Characteristics of polysomnography in depression patients complicating moderate-to-severe obstructive sleep apnea hypopnea syndrome[J]. Sichuan Mental Health, 2021, 34(5): 424-428.
    [14]
    栗恺雯. 重性精神障碍患者的睡眠结构比较及预测模型建立[D]. 太原: 山西医科大学, 2023.

    LI K W. Comparison of sleep structure in patients with severe mental disorders and establishment of prediction model[D]. Taiyuan: Shanxi Medical University, 2023.
    [15]
    孙奕, 郑慧芬. 失眠伴轻度认知功能障碍老年患者的睡眠分析[J]. 中华全科医学, 2023, 21(10): 1640-1642, 1809. doi: 10.16766/j.cnki.issn.1674-4152.003188

    SUN Y, ZHENG H F. Analysis of sleep characteristics in elderly patients with insomnia and mild cognitive impairment[J]. Chinese Journal of General Practice, 2023, 21(10): 1640-1642, 1809. doi: 10.16766/j.cnki.issn.1674-4152.003188
    [16]
    孔令明, 朱晓丽, 何明骏, 等. 心理资本、宽恕倾向与老年人晚发性抑郁症的关系[J]. 中华保健医学杂志, 2021, 23(1): 18-21.

    KONG L M, ZHU X L, HE M J, et al. Correlation of psychological capital, forgiveness trait and late-onset depression in older adults[J]. Chinese Journal of Health Care and Medicine, 2021, 23(1): 18-21.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (1) PDF downloads(0) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return