Volume 22 Issue 8
Aug.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(8): 1395-1398
LIU Kai, WU Jing, XU Xun, GUAN Zheng, XU Li, ZHANG Jun. Analysis of screening and identification of irregular antibodies in 39 671 blood transfusion patients[J]. Chinese Journal of General Practice, 2024, 22(8): 1395-1398. doi: 10.16766/j.cnki.issn.1674-4152.003644
Citation: LIU Kai, WU Jing, XU Xun, GUAN Zheng, XU Li, ZHANG Jun. Analysis of screening and identification of irregular antibodies in 39 671 blood transfusion patients[J]. Chinese Journal of General Practice, 2024, 22(8): 1395-1398. doi: 10.16766/j.cnki.issn.1674-4152.003644
shu

Analysis of screening and identification of irregular antibodies in 39 671 blood transfusion patients

doi: 10.16766/j.cnki.issn.1674-4152.003644

  • Department of Blood Transfusion, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China

Funds:

 KJ2020A0561

  • Received Date: 2023-11-17
    Available Online: 2024-11-19
    Abstract
  •   Objective   To analyze the screening and identification results of irregular antibodies in patients with blood transfusion, and to explore the relationship between irregular antibodies and gender, blood transfusion history, and pregnancy history.   Methods   The screening and identification results of irregular antibodies in 39 671 transfusion patients from January 2021 to December 2022 were obtained from the hospital electronic medical record system. The number of positive cases for irregular antibodies was recorded, the distribution of irregular antibodies was analyzed, and the relationship between the positive rate and specificity of irregular antibodies and patient gender, transfusion history, and pregnancy history was explored.   Results   Among the 39 671 transfusion patients, a total of 365 cases tested positive for irregular antibodies, with a positivity rate of 0.92%. Among them, the highest proportion was positive antibodies in the Rh blood type system (213 cases, accounting for 58.36%). The data showed that among the 365 patients with positive irregular antibodies, females (228 cases, 62.47%) had a higher proportion than males (137 cases, 37.53%), and the positivity rate of Rh blood type system antibodies in female patients (143 cases, 62.72%) was significantly higher than that in males (70 cases, 51.09%; P=0.037). Patients with a history of transfusion and those with a history of pregnancy were more likely to have positive Rh blood type system antibodies (P < 0.05).   Conclusion   Women, blood transfusion history and pregnancy history will increase the probability of positive results on irregular antibody screening. While irregular antibody screening and identification for patients who have conventional transfusion therapy are carried out, the detection for women, patients with blood transfusion history or pregnancy history should be especially strengthened.

     

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