The predictive value of uric acid to albumin ratio for medium and long-term all-cause mortality in patients with CTO

ZHANG Jingjing; ZHAO Yufei; ZHU Hualiang; ZHU Xiaoxia; LIU Zeyan; HUANG Zheng

doi:10.16766/j.cnki.issn.1674-4152.003667

Volume 22 Issue 9

Sep. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(9): 1496-1499

ZHANG Jingjing, ZHAO Yufei, ZHU Hualiang, ZHU Xiaoxia, LIU Zeyan, HUANG Zheng. The predictive value of uric acid to albumin ratio for medium and long-term all-cause mortality in patients with CTO[J]. Chinese Journal of General Practice, 2024, 22(9): 1496-1499. doi: 10.16766/j.cnki.issn.1674-4152.003667

Citation:

ZHANG Jingjing, ZHAO Yufei, ZHU Hualiang, ZHU Xiaoxia, LIU Zeyan, HUANG Zheng. The predictive value of uric acid to albumin ratio for medium and long-term all-cause mortality in patients with CTO[J]. Chinese Journal of General Practice, 2024, 22(9): 1496-1499. doi: 10.16766/j.cnki.issn.1674-4152.003667

Citation:

ZHANG Jingjing, ZHAO Yufei, ZHU Hualiang, ZHU Xiaoxia, LIU Zeyan, HUANG Zheng. The predictive value of uric acid to albumin ratio for medium and long-term all-cause mortality in patients with CTO[J]. Chinese Journal of General Practice, 2024, 22(9): 1496-1499. doi: 10.16766/j.cnki.issn.1674-4152.003667

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The predictive value of uric acid to albumin ratio for medium and long-term all-cause mortality in patients with CTO

doi: 10.16766/j.cnki.issn.1674-4152.003667

1.
Cardiovascular Department for Gerontism, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230011, China

Funds:

2022AH050770

Received Date: 2024-01-30

Abstract

Abstract

Objective Uric acid to albumin ratio (UAR) can reflect the inflammation and oxidation status, this study was to analyze its expression level in patients with chronic coronary artery occlusion (coronary chronic total occlusion, CTO), and evaluate its prediction value for long-term death in patients. Methods A total of 259 CTO patients undergoing coronary angiography in the Second Affiliated Hospital of Anhui Medical University from January 2019 to March 2023 were selected, and the patients were divided into survival group and death group according to their prognosis. Univariate regression analysis and multivariate logistic regression analysis were used to evaluate the effect of UAR on mortality adverse events in CTO patients. Results Among the 259 CTO patients, 39 (15.06%) died and 220 (84.94%) survived during the follow-up period of approximately of (39.9±12.3) months. Compared with the survival group, patients in the death group exhibited a older age, higher proportion of dual -vessel lesions of CTO, higher levels of blood urea nitrogen, creatinine, uric acid, UAR, and neutrophil-to-lymphocyte ratio (NLR), fewer cases of complete revascularization, and lower levels of albumin and triglycerides (P < 0.05). Multivariate logistic regression analysis showed that the risk factors for poor prognosis in CTO patients include increasing age, increased number of CTO lesions and elevated UAR. The area under the ROC curve for UAR predicting mid to long-term all-cause mortality in CTO patients was 0.648 (95% CI: 0.547-0.748, P=0.003), with a sensitivity of 53.8% and a specificity of 72.7%. Conclusion The UAR of the deceased is significantly higher compared to survivors, indicating that UAR holds certain predictive value for mid to long-term all-cause mortality in patients with chronic total occlusion of the coronary arteries.
- Uric acid to albumin ratio,
- Chronic total occlusion of coronary arteries,
- Regression analysis

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References

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