Analysis of curative effects on KangF u XiaoY an suppository combined with azithromycin in the treatment of pelvic inflammation disease complicated by mycoplasma infection

Objective To compare the curative effect of KangFu XiaoYan suppository combined with azithromycin and azithromycin alone in the pelvic inflammation disease complicated by mycoplasma infection. Methods From January,2014 to December,2015,112 cases were selected in our hospital as the research object. According to admission order, 112 patients were divided into the control group(n=56)and the treatment group(n=56). The control group were given intravenous infusion of azithromycin,0.5 g/times,1 times/d, 2 days after the use of azithromycin oral preparation,0.25 g/times,1 times/d. Treatment group on the basis of the control group to give KangFu XiaoYan suppository embolism anus,1 per night. In two groups, 1 courses of treatment is 7 days, a total of 6 courses. After the treatment,the clinical efficacy, safety and changes of T lymphocyte subsets in peripheral blood were compared between the two groups.The data were processed by SPSS 17.0 statistical software. Results The clinical efficiency of the treatment group was significantly better than that of the control group (P<0.05).The incidence rate of adverse effect in the treatment group was lower than that in control group(8.93% vs. 12.50%),but the difference was not statistically significant (P>0.05).The two groups of patients after treatment, blood, urine, stool, liver function no obvious abnormal,high safety.Treatment of peripheral blood T cells subsets CD4⁺ percentages (45.51±5.15%) was significantly higher than those in control group (43.89%±4.06%),CD8⁺T cell ratio for(35.92%±3.05%) was significantly lower than that in control group (37.06%±3.25%),the ratio of CD4⁺/CD8⁺ was significantly higher than that of control group,the difference was statistically significant(P<0.05). Conclusion KangFu XiaoYan suppository combined with azithromycin in the treatment of pelvic inflammation disease complicated by mycoplasma infection has good curative effects,with safety,few side effects,the proportion of T cell subsets in peripheral blood was significantly improved.