Prognostic analysis of different surgical approaches in treating colorectal cancer peritoneal metastasis

Objective To analyze the different surgical methods on the prognosis of patients with peritoneal metastasis of colorectal cancer. Methods Retrospective analysis of 98 cases of peritoneal metastasis in patients with rectal cancer from May, 2010 to June, 2014 in our hospital, they were devided into complete resection group (35 cases), incomplete resection group (34 cases) and subtraction surgery group (29 cases) according to the different surgical methods, the clinicopathological data and postoperative survival of the three groups were analyzed, and Cox proportional risk model was used to analyze the prognosis of patients with colorectal cancer. Results In this study, 98 patients were followed up, and the follow-up rate was 100%, the follow-up time was 0.5-40.0 months, the mean survival time was (16.9±4.5) months, and the total survival rate was 40.8% (40/98) and 18.4% (18/98) in 1 year and 3 years respectively; Complete resection group average survival time was (28.6±6.2) months, the total survival rate was 71.4% (25/35) and 45.7% (16/35) in 1 year and 3 years, incomplete resection group average survival time was (11.2±4.1) months, the total survival rate was 26.5% (9/34) and 0 in 1 year and 3 years, subtraction surgery group average survival time was (10.9±3.2) months, the total survival rate was 13.8% (4/29) and 0 in 1 year and 3 years, the mean survival time, 1 year and 3 years of total survival rate in complete resection group were significantly higher than those in incomplete resection group and subtraction group (P<0.05), the mean survival time, 1 year, 3 years of total survival rate in incomplete resection group were not statistically significant with subtraction surgery group (P>0.05); Cox analysis showed that differentiation degree, PCI, primary stage T stage and operation mode were the main factors affecting the prognosis of patients with peritoneal metastasis of colorectal cancer. Conclusion Peritoneal metastasis of colorectal cancer patients with complete resection of the prognosis is better, and it is worthy of clinical application.