Volume 19 Issue 8
Aug.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(8): 1269-1272,1321
LUO Guiying, WANG Jieyu, WANG Chunyan, SONG Linlin, YUAN Lanlan, CAO Yunxia. Analysis of influencing factors of pain in patients after oocyte retrieval of in vitro fertilization-embryo transfer[J]. Chinese Journal of General Practice, 2021, 19(8): 1269-1272,1321. doi: 10.16766/j.cnki.issn.1674-4152.002037
Citation: LUO Guiying, WANG Jieyu, WANG Chunyan, SONG Linlin, YUAN Lanlan, CAO Yunxia. Analysis of influencing factors of pain in patients after oocyte retrieval of in vitro fertilization-embryo transfer[J]. Chinese Journal of General Practice, 2021, 19(8): 1269-1272,1321. doi: 10.16766/j.cnki.issn.1674-4152.002037
shu

Analysis of influencing factors of pain in patients after oocyte retrieval of in vitro fertilization-embryo transfer

doi: 10.16766/j.cnki.issn.1674-4152.002037

  • Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 2016YFC1000204

 KJ2020A0203

 SK2020A0146

  • Received Date: 2020-11-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  To explore the influencing factors of pain after transvaginal aspiration for oocyte retrieval, and to provide theoretical basis for clinical analgesia intervention.  Methods  A total of 755 patients who underwent in vitro fertilization-embryo transfer vaginal puncture for oocyte retrieval in the Reproduction Center of the First Affiliated Hospital of Anhui Medical University from April to July 2020 were selected. The scores of their self-rating anxiety scale and self-rating depression scale were evaluated at 20:00 on trigger day. The numeric rating scale was used to evaluate the pain degree at 30 minutes and 1 hour after oocyte retrieval, and the adverse reactions such as nausea and vomiting were recorded at 30 minutes after operation. The pain degree at 6, 12 and 24 hours after surgery was followed up by telephone with numeric rating scale. Univariate ordered multiple logistic regression analysis and multivariate ordered multiple logistic regression analysis were used to investigate the influencing factors of pain.  Results  Univariate ordered multi-classification logistic regression analysis showed that age years, family per capita monthly income, pethidine hydrochloride analgesia, operation time, number of follicles obtained and total ovarian volume were the potential influencing factors of postoperative pain (all P < 0.05). Multivariate ordered multi-classification logistic regression analysis showed that the number of follicles obtained (OR=0.692, 95% CI: -0.784 to -0.048), ovarian volume (< 2 000 mm3, OR=0.252, 95% CI: -1.846 to -0.908; 2 000-3 999 mm3, OR=0.632, 95% CI: -0.803 to -0.113) were the influencing factors of postoperative pain (all P < 0.05).  Conclusion  The greater the number of follicles obtained (≥ 20) and the larger the ovarian volume (≥ 4 000 mm3), the more intense the pain may be. Controlling the number of follicles and the volume of ovaries during superovulation may reduce pain in patients.

     

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