Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease

DING Cheng; MA Yuzhuo; HUANG Xingzhao; HUANG Jinping; ZHONG Liangjun; CHEN Xing

doi:10.16766/j.cnki.issn.1674-4152.002040

Volume 19 Issue 8

Aug. 2021

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Article Navigation > Chinese Journal of General Practice > 2021 > 19(8): 1280-1282, 1299

DING Cheng, MA Yuzhuo, HUANG Xingzhao, HUANG Jinping, ZHONG Liangjun, CHEN Xing. Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease[J]. Chinese Journal of General Practice, 2021, 19(8): 1280-1282, 1299. doi: 10.16766/j.cnki.issn.1674-4152.002040

Citation:

DING Cheng, MA Yuzhuo, HUANG Xingzhao, HUANG Jinping, ZHONG Liangjun, CHEN Xing. Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease[J]. Chinese Journal of General Practice, 2021, 19(8): 1280-1282, 1299. doi: 10.16766/j.cnki.issn.1674-4152.002040

Citation:

DING Cheng, MA Yuzhuo, HUANG Xingzhao, HUANG Jinping, ZHONG Liangjun, CHEN Xing. Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease[J]. Chinese Journal of General Practice, 2021, 19(8): 1280-1282, 1299. doi: 10.16766/j.cnki.issn.1674-4152.002040

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Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease

doi: 10.16766/j.cnki.issn.1674-4152.002040

1.
Department of Stomatology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310000, China

Funds:

2019KY497

Received Date: 2020-12-28
Available Online: 2022-02-16

Abstract

Abstract

Objective To evaluate the effects of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease (NAFLD). Methods Thirty moderate or severe periodontitis cases with NAFLD were selected from July 2018 to June 2019 in Department of Periodontics, Affiliated Hospital of Hangzhou Normal University. All enrolled patients were treated with periodontal basic treatment. Periodontal clinical index, lipid levels and liver function examination were determined at baseline and 3 months after treatment. Paired t test was used to compare the data. Results Compared with periodontal basic treatment, the periodontal probing depth decreased from (3.76±0.46) mm to (2.30±0.37) mm, the clinical attachment level decreased from (4.90±0.48) mm to (3.90±0.49) mm, and the percentage of bleeding on probing decreased from (88.93±5.05) % to (20.47±5.98) %. Meanwhile, the alanine aminotransferase decreased from (61.60±12.07) U/L to (45.82±11.82) U/L, and the aspartate aminotransferase decreased from (54.71±11.20) U/L to (44.87±11.36) U/L. In addition, total cholesterol reduced from (5.63±0.24) mmol/L to (5.23±0.24) mmol/L, triacylglycerol decreased from (1.90±0.10) mmol/L to (1.63±0.13) mmol/L, low-density lipoprotein decreased from (2.78±0.30) mmol/L to (1.78±0.43) mmol/L, and high-density lipoprotein increased from (1.25±0.05) mmol/L to (1.39±0.06) mmol/L. Conclusion Periodontitis patients with NAFLD can obtain good clinical efficacy through periodontal basic treatment, which not only significantly improves their periodontal status, but also improves their liver function and blood lipid level. Therefore, periodontal basic treatment may be one of the treatment approaches for periodontitis patients with NAFLD.
- Periodontal initial therapy,
- Non-alcoholic fatty liver,
- Chronic periodontitis,
- Liver function,
- Blood lipid

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Effect of periodontal basic treatment on liver function and lipid levels in periodontitis patients with non-alcoholic fatty liver disease

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