Volume 19 Issue 9
Sep.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(9): 1466-1469,1487
JIANG Yu-yu, YU Ru, YIN Tian-yue, LI Xiao-yu, CHENG Xiang-yang. Effect of continuous serratus anterior plane block on postoperative recovery in elderly patients undergoing thoracoscopic radical resection of lung cancer[J]. Chinese Journal of General Practice, 2021, 19(9): 1466-1469,1487. doi: 10.16766/j.cnki.issn.1674-4152.002087
Citation: JIANG Yu-yu, YU Ru, YIN Tian-yue, LI Xiao-yu, CHENG Xiang-yang. Effect of continuous serratus anterior plane block on postoperative recovery in elderly patients undergoing thoracoscopic radical resection of lung cancer[J]. Chinese Journal of General Practice, 2021, 19(9): 1466-1469,1487. doi: 10.16766/j.cnki.issn.1674-4152.002087
shu

Effect of continuous serratus anterior plane block on postoperative recovery in elderly patients undergoing thoracoscopic radical resection of lung cancer

doi: 10.16766/j.cnki.issn.1674-4152.002087

  • Department of Anesthesiology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 202010367012

 KJ2018A0212

  • Received Date: 2020-08-18
    Available Online: 2022-02-15
    Abstract
  •   Objective  To explore the effect of continuous serratus anterior plane block (SAPB) guided by ultrasound on postoperative analgesia and recovery in elderly patients undergoing thoracoscopic radical resection of lung cancer.   Methods  From October 2019 to June 2020, 60 patients in the First Affiliated Hospital of Bengbu Medical College undergoing thoracoscopic radical resection of lung cancer were selected and divided into the P group and SP group with 30 cases each by a simple random method. Patients in the P group received intravenous patient-controlled analgesia, whilst those in the SP group received continuous SAPB analgesia. The VAS scores of rest and activity, quality of postoperative recovery (QoR-40) scores, CD4+, CD4+/CD8+ and postoperative adverse events were compared between the two groups before and after 1, 3 and 7 days of surgery.   Results  The resting and active pain scores of the SP group were 1.6±0.2, 2.3±0.4, 1.4±0.3 and 1.9±0.3, which were lower than those of the P group (2.5±0.3, 3.7±0.3, 2.1±0.2, 2.9±0.4, all P < 0.05). The QOR-40 scores, CD4+ and CD4+/CD8+ in the SP group were 170.7±3.2, 173.3±2.9, 40.8±6.4, 42.3±6.4, 1.5±0.1, 1.6±0.1 at 1 and 3 days after surgery, which were higher than those in the P group (162.8±3.7, 167.9±2.7 and 36.2±6.2, 39.0±5.0, 1.3±0.2, 1.4±0.2, all P < 0.05). The postoperative adverse reaction rate in the SP group was 4.6%, which was significantly lower than that in the P group (17.3%, P < 0.05).   Conclusion  As a postoperative analgesic strategy, continuous SAPB guided by ultrasound can significantly reduce postoperative pain, reduce stress response and immunosuppression, and promote early recovery of elderly patients undergoing thoracoscopic radical resection of lung cancer.

     

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    • References(16)
  • [1]
    GOTO T. What is the best pain control after thoracic surgery?[J]. J Thorac Dis, 2018, 10(3): 1335-1338. doi: 10.21037/jtd.2018.03.63
    [2]
    HANLEY C, WALL T, BUKOWSKA I, et al. Ultrasound-guided continuous deep serratus anterior plane block versus continuous thoracic paravertebral block for perioperative analgesia in videoscopic-assisted thoracic surgery[J]. Eur J Pain, 2020, 24(4): 828-838. doi: 10.1002/ejp.1533
    [3]
    KHALIL A E, ABDALLAH N M, BASHANDY G M, et al. Ultrasound-guided serratus anterior plane block versus thoracic epidural analgesia for thoracotomy pain[J]. J Cardiothorac Vasc Anesth, 2017, 31(1): 152-158. doi: 10.1053/j.jvca.2016.08.023
    [4]
    SAAD F S, EL BARADIE S Y, ABDEL ALIEM M A W, et al. Ultrasound-guided serratus anterior plane block versus thoracic paravertebral block for perioperative analgesia in thoracotomy[J]. Saudi J Anaesth, 2018, 12(4): 565-570.
    [5]
    ÖKMEN K, ÖKMEN B M, The efficacy of serratus anterior plane block in analgesia for thoracotomy: A retrospective study[J]. J Anesth, 2017, 31(4): 579-585. doi: 10.1007/s00540-017-2364-9
    [6]
    朱云柯, 林琳, 廖虎, 等. 中国胸外科围手术期疼痛管理专家共识(2018版)[J]. 中国胸心血管外科临床杂志, 2018, 25(11): 921-928. doi: 10.7507/1007-4848.201810052
    [7]
    PARK B, LEE G, KIM H K, et al. A retrospective comparative analysis of elderly and younger patients undergoing pulmonary resection for stage Ⅰ non-small cell lung cancer[J]. World J Surg Oncol, 2015, 14(1): 13. doi: 10.1186/s12957-015-0762-8
    [8]
    IMAM M Z, KUO A, GHASSABIAN S, et al. Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression[J]. Neuropharmacology, 2018, 131: 238-255. doi: 10.1016/j.neuropharm.2017.12.032
    [9]
    BOLAND J W, POCKLEY A G. Influence of opioids on immune function in patients with cancer pain: From bench to bedside[J]. Br J Pharmacol, 2018, 175(14): 2726-2736. doi: 10.1111/bph.13903
    [10]
    KELLY M E, MC NICHOLAS D, KILLEN J, et al. Thoracic paravertebral blockade in breast surgery: Is pneumothorax an appreciable concern? A review of over 1 000 cases[J]. Breast J, 2018, 24(1): 23-27. doi: 10.1111/tbj.12831
    [11]
    KUPERSZTYCH-HAGEGE E, DUBUISSON E, SZEKELY B, et al. Epidural hematoma and abscess related to thoracic epidural analgesia: A single-center study of 2, 907 patients who underwent lung surgery[J]. J Cardiothorac Vasc Anesth, 2017, 31(2): 446-452. doi: 10.1053/j.jvca.2016.07.022
    [12]
    WANG L P, WANG Y, ZHANG X, et al. Serratus anterior plane block or thoracic paravertebral block for postoperative pain treatment after uniportal video-assisted thoracoscopic surgery: A retrospective propensity-matched study[J]. J Pain Res, 2019, 12: 2231-2238. doi: 10.2147/JPR.S209012
    [13]
    CHU G M, JARVIS G C. serratus anterior plane block to address postthoracotomy and chest tube-related pain: A report on 3 cases[J]. A A Case Rep, 2017, 8(12): 322-325. doi: 10.1213/XAA.0000000000000502
    [14]
    KIM D H, OH Y J, LEE J G, et al. Efficacy of ultrasound-guided serratus plane block on postoperative quality of recovery and analgesia after video-assisted thoracic surgery: A randomized, triple-blind, placebo-controlled study[J]. Anesth Analg, 2018, 126(4): 1353-1361. doi: 10.1213/ANE.0000000000002779
    [15]
    OWUSU O A, HAMADEH I, SMITH M. Review of opioid pharmacogenetics and considerations for pain management[J]. Pharmacotherapy, 2017, 37(9): 1105-1121. doi: 10.1002/phar.1986
    [16]
    MYLES P S, MYLES D B, GALAGHER W, et al. Minimal clinically important difference for three quality of recovery scales[J]. Anesthesiology, 2016, 125(1): 39-45. doi: 10.1097/ALN.0000000000001158
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