Volume 19 Issue 9
Sep.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(9): 1500-1503
HUANG Yi-gui, CHEN Yu, FU Zheng-gao, ZHONG Pei-xiong, HAO Jin-xiang, XU Mei-sha, ZHOU You-ling. Risk factors of carbapenem-resistant Acinetobacter baumannii infection in a hospital[J]. Chinese Journal of General Practice, 2021, 19(9): 1500-1503. doi: 10.16766/j.cnki.issn.1674-4152.002096
Citation: HUANG Yi-gui, CHEN Yu, FU Zheng-gao, ZHONG Pei-xiong, HAO Jin-xiang, XU Mei-sha, ZHOU You-ling. Risk factors of carbapenem-resistant Acinetobacter baumannii infection in a hospital[J]. Chinese Journal of General Practice, 2021, 19(9): 1500-1503. doi: 10.16766/j.cnki.issn.1674-4152.002096
shu

Risk factors of carbapenem-resistant Acinetobacter baumannii infection in a hospital

doi: 10.16766/j.cnki.issn.1674-4152.002096

  • Department of Respiratory, the Third People's Hospital of Haikou, Haikou, Hainan 571100, China

Funds:

 17A200817

  • Received Date: 2020-12-21
    Available Online: 2022-02-15
    Abstract
  •   Objective  To explore and analyse risk factors affecting carbapenem-resistant Acinetobacter baumannii (CRAB) infection in our hospital and to provide evidence for infection prevention and control and clinical treatment.   Methods  From January 2017 to December 2019, 572 patients with Acinetobacter baumannii (AB) infection in our hospital were selected as the research objects. According to the results of drug sensitivity, they were divided into the CRAB group (387 cases) and carbapenem-sensitive Acinetobacter baumannii (CSAB) group (185 cases). The clinical data of both groups were collected. Single-factor and multivariate logistic regression were used to analyse the risk factors of CRAB infection.   Results  Amongst 572 patients with AB infection, the CRAB infection rate was 67.66% (387/572). Univariate analysis showed that history of diabetes, chronic lung disease, use of incision drainage tube, bronchoscopy, use of adrenal glucocorticoids, use of tigecycline, use of carbapenem antibiotics and use β-lactamase inhibitor antibiotics of CRAB group and CSAB group were statistically significant (all P < 0.05). Multivariate logistic regression analysis showed that diabetes history (OR=2.884, 95% CI: 1.105-7.206), use of incision drainage tube (OR=5.106, 95% CI: 1.834-14.270), bronchoscopy (OR=4.497, 95% CI: 1.704-12.365), use of tigecycline (OR=3.514, 95% CI: 1.482-8.945) and use of carbapenem antibiotics (OR=5.282, 95% CI: 2.146-15.308) were risk factors for CRAB infection (all P < 0.05).   Conclusion  Many risk factors are associated with CRAB infection. The management of patients with CRAB infection should be strengthened, and antibiotics should be used rationally to reduce the CRAB infection rate.

     

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