Volume 19 Issue 9
Sep.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(9): 1565-1568
LENG Yu-ling, WU Yong, ZHOU Xian-yang, XU heng, HAO Wan-rong, DING Yan-qi, ZENG Yong-lei, XIA Ke-chun. Effect of Pei86tu Guben Moxibustion on chemotherapy-related cancer-related fatigue of gastrointestinal tumour[J]. Chinese Journal of General Practice, 2021, 19(9): 1565-1568. doi: 10.16766/j.cnki.issn.1674-4152.002113
Citation: LENG Yu-ling, WU Yong, ZHOU Xian-yang, XU heng, HAO Wan-rong, DING Yan-qi, ZENG Yong-lei, XIA Ke-chun. Effect of Pei86tu Guben Moxibustion on chemotherapy-related cancer-related fatigue of gastrointestinal tumour[J]. Chinese Journal of General Practice, 2021, 19(9): 1565-1568. doi: 10.16766/j.cnki.issn.1674-4152.002113
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Effect of Pei86tu Guben Moxibustion on chemotherapy-related cancer-related fatigue of gastrointestinal tumour

doi: 10.16766/j.cnki.issn.1674-4152.002113

  • Oncology Department, the Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230031, China

Funds:

 皖卫教研2017[30号]

 1608085MH233

  • Received Date: 2020-12-23
    Available Online: 2022-02-15
    Abstract
  •   Objective  To investigate the clinical effect of the Peitu Guben Moxibustion in the chemotherapy-related cancer-related fatigue and its effect on the levels of adrenocorticotropic hormone (ACTH) and cortisol hormone (COR).  Methods  Total 50 patients with cancer-related fatigue caused by gastrointestinal cancer who were admitted to the Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2018 to November 2020 were selected and divided into treatment group (25 cases) and control group (25 cases) according to random number table method. The two groups were treated with standard chemotherapy regimen. On this basis, the treatment group was treated with the Peitu Guben Moxibustion therapy regimen, once a day, once a week as a course of treatment, for two courses of continuous treatment. After the treatment, the change of cancer-related fatigue degree and quality of life (EORTC-QLQ-C30) before and after treatment were compared between two groups. The levels of ACTH and COR were compared between the two groups before and after treatment, and investigated the correlation with cancer-related fatigue.  Results  After treatment, the mild fatigue, medium fatigue and severe fatigue patients in the treatment group were respectively 14 cases, 8 cases and 3 cases; in the control group, the mild fatigue, medium fatigue and severe fatigue patients were respectively 2 cases, 14 cases and 9 cases. The difference between the two groups after treatment was statistically significant (Z=-3.435, P=0.001). After treatment, the improvement of physical function, role function and emotional function in the treatment group was better than that in the control group (all P < 0.05). There were no significant changes in cognitive function and social function (all P>0.05). After treatment, the COR level of treatment group was higher than that of control group (P < 0.05), while the ACTH level of treatment group was lower than that of control group (P < 0.05).  Conclusion  The Peitu Guben Moxibustion in the treatment of chemotherapy-related cancer-related fatigue can effectively improve the fatigue symptoms and improve the quality of life score of patients, and increase the level of COR and decrease the level of ACTH in patients. The changes of COR and ACTH levels may be related to the degree of cancer-related fatigue.

     

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