Volume 19 Issue 10
Oct.  2021
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(10): 1725-1728
WU Xiu-ji, WANG Yong-qing, QIU Mei-hua. Predictive value of reticulocyte parameters and relative value of immature granulocytes in adverse pregnancy outcome[J]. Chinese Journal of General Practice, 2021, 19(10): 1725-1728. doi: 10.16766/j.cnki.issn.1674-4152.002152
Citation: WU Xiu-ji, WANG Yong-qing, QIU Mei-hua. Predictive value of reticulocyte parameters and relative value of immature granulocytes in adverse pregnancy outcome[J]. Chinese Journal of General Practice, 2021, 19(10): 1725-1728. doi: 10.16766/j.cnki.issn.1674-4152.002152
shu

Predictive value of reticulocyte parameters and relative value of immature granulocytes in adverse pregnancy outcome

doi: 10.16766/j.cnki.issn.1674-4152.002152

  • Department of Clinical Laboratory, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou, Hainan 570208, China

Funds:

 18A200020

  • Received Date: 2020-07-15
    Available Online: 2022-02-15
    Abstract
  •   Objective  To investigate the predictive value of reticulocyte parameters and immature granulocytes in pregnant women with adverse pregnancy outcomes.  Methods  A total of 100 non-pregnant women, 300 normal pregnant women and 201 unhealthy pregnant women were divided into three groups. The reticulocyte percentage (Ret%), immature reticulocyte index (IRF), reticulocyte haemoglobin (Ret-He), and relative value (%IG) of immature granulocytes and haemoglobin (Hb) were detected by XN-9000 automatic haematology analyser (Sysmex, Japan). The ROC curve was used to explore the predictive value of reticulocyte parameters and relative value of immature granulocytes for adverse pregnancy outcomes of pregnant women.  Results  Compared with the non-pregnancy group, the unhealthy pregnant women group had significantly reduced Hb and Ret-He and increased IRF (P < 0.05), whilst the normal pregnancy group had significantly reduced Hb and significantly increased Ret%, IRF and %IG (P < 0.05). Compared with the normal pregnancy group, the unhealthy pregnant women group had significantly reduced Hb, Ret%, IRF, Ret-He and %IG (P < 0.05). The areas under the ROC curve of Ret%, IRF, Ret-He and %IG were 0.611, 0.619, 0.727 and 0.821, respectively. The best predicted cut-off values were 1.695, 14.100, 32.450 and 1.350. The sensitivity values were 0.814, 0.833, 0.502 and 0.671, whereas the specificity values were 0.375, 0.667, 0.875 and 0.896.  Conclusion  The Ret%, IRF, Ret-He and %IG are related to the occurrence of adverse pregnancy outcomes. The %IG predicts the occurrence of adverse pregnancy outcomes with the greatest specificity, whilst IRF has the highest sensitivity. Reticulocyte parameters combined with the detection of the relative value of immature granulocytes have certain value in predicting the adverse pregnancy outcomes of pregnant women.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    张芝银, 李秀央, 郑国英, 等. 不良妊娠结局的影响因素分析[J]. 预防医学, 2020, 32(1): 94-97. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX202001029.htm
    [2]
    祁娟. 不同年龄孕产妇血液学指标与妊娠结局的关系比较[J]. 检验医学与临床, 2018, 15(14): 2077-2079, 2082. doi: 10.3969/j.issn.1672-9455.2018.14.016
    [3]
    于晓红, 赵静, 张翠玲. 早发型子痫前期终止妊娠血清学指标的临床研究[J]. 中华全科医学, 2019, 17(5): 805-808. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY201905028.htm
    [4]
    朱姣. 红细胞分布宽度在子痫前期孕妇的妊娠结局中的预测价值[J]. 齐齐哈尔医学院学报, 2018, 39(18): 2139-2140. doi: 10.3969/j.issn.1002-1256.2018.18.013
    [5]
    彭碧, 马永能, 何芳, 等. 网织红细胞相关参数在珠蛋白生成障碍性贫血和缺铁性贫血中的诊断价值[J]. 国际检验医学杂志, 2018, 39(2): 153-155. https://www.cnki.com.cn/Article/CJFDTOTAL-GWSQ201802009.htm
    [6]
    杨勇, 蔡世川, 辛琴. 网织红细胞参数与红细胞参数在妊娠期缺铁性贫血中的临床应用研究[J]. 中国医药指南, 2018, 16(1): 16-17. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK201801011.htm
    [7]
    刘小芳, 刘蕾, 王凌云, 等. 围产期妇女血液系统问题的处理思考[J]. 临床医药文献电子杂志, 2019, 6(75): 12-13. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWX201975007.htm
    [8]
    SHIM J Y, MADRIGAL J M, APARICIO J, et al. Beyond routine abortion practice: Identifying adolescents and young adults at risk for anemia[J]. J Pediatr Adolesc Gynecol, 2018, 31(5): 468-472. doi: 10.1016/j.jpag.2018.06.002
    [9]
    胡美娜, 赵银珠, 邹晓璇, 等. 低出生体重发生率及影响因素[J]. 中国生育健康杂志, 2019, 30(2): 127-130. https://www.cnki.com.cn/Article/CJFDTOTAL-SYJK201902006.htm
    [10]
    成丽虹, 张淑仪, 吴羽雷, 等. 妊娠晚期贫血孕妇维生素A营养状况及网织红细胞参数分析[J]. 国际妇产科学杂志, 2020, 47(2): 199-202. https://www.cnki.com.cn/Article/CJFDTOTAL-GWVC202002020.htm
    [11]
    蒋永悟. 妊娠贫血患者不同孕期血常规及凝血功能变化研究[J]. 陕西医学杂志, 2019, 48(8): 1052-1055. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYZ201908026.htm
    [12]
    叶金丹, 王秀娟. 早期综合管理对妊娠期贫血患者干预效果评价[J]. 中国农村卫生事业管理, 2019, 39(7): 519-522. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNWS201907016.htm
    [13]
    AYRES L S, SGNAOLIN V, MUNHOZ T P. Immature granulocytes index as early marker of sepsis[J]. Int J Lab Hematol, 2019, 41(3): 392-396.
    [14]
    BLAZKOVA J, GUPTA S, LIU Y, et al. Multicenter systems analysis of human blood reveals immature neutrophils in males and during pregnancy[J]. J Immunol, 2017, 198(6): 2479-2488. http://pubmedcentralcanada.ca/pmcc/articles/PMC5337813/
    [15]
    张瀚月, 张璐璐, 许瑞, 等. 网织红细胞血红蛋白含量等指标在妊娠期缺铁性贫血筛检中的意义[J]. 中国医药, 2019, 14(5): 763-767. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYG201905030.htm
    [16]
    蒋智锋. 网织红细胞血红蛋白含量在铁缺乏诊断中的临床价值[J]. 医学理论与实践, 2020, 33(4): 635-636. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL202004064.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(2)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (238) PDF downloads(1) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return