Volume 19 Issue 11
Nov.  2021
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SONG Jian-long, WANG Zi, WEI Jian-lin, LIU Chang, HU Wei, XIA Cheng-yu, ZHU Yu-you. Analysis on the characteristics of middle cerebral arterial plaque in young and middle-aged patients with acute ischemic cerebrovascular disease[J]. Chinese Journal of General Practice, 2021, 19(11): 1811-1814. doi: 10.16766/j.cnki.issn.1674-4152.002173
Citation: SONG Jian-long, WANG Zi, WEI Jian-lin, LIU Chang, HU Wei, XIA Cheng-yu, ZHU Yu-you. Analysis on the characteristics of middle cerebral arterial plaque in young and middle-aged patients with acute ischemic cerebrovascular disease[J]. Chinese Journal of General Practice, 2021, 19(11): 1811-1814. doi: 10.16766/j.cnki.issn.1674-4152.002173

Analysis on the characteristics of middle cerebral arterial plaque in young and middle-aged patients with acute ischemic cerebrovascular disease

doi: 10.16766/j.cnki.issn.1674-4152.002173
Funds:

 1804h08020250

 201904a07020086

  • Received Date: 2020-07-05
  •   Objective  To study the characteristics of middle cerebral artery plaques in young and middle-aged adults with acute ischemic cerebrovascular disease using high-resolution magnetic resonance vessel wall imaging.   Methods  We collected 74 young and middle-aged patients with acute ischemic stroke or transient ischemic attack hospitalised from June 2018 to February 2020 using high-resolution magnetic resonance imaging to evaluate the location and nature of plaques and to compare the location distribution characteristics of symptomatic and asymptomatic middle cerebral arteries and plaques of different properties.   Results  There were 74 patients, including 62 cases of intracranial atherosclerotic plaque. A total of 124 middle cerebral arteries were scanned by magnetic resonance imaging in 62 patients, of which 48 were symptomatic side vessel roots (38.7%) and 76 were non-symptomatic lateral vessels (61.3%). There were 96 plaques, 39 stable plaques (40.6%), 57 unstable plaques (59.4%), 16 superior plaques (16.7%), 38 inferior plaques (39.6%), 10 dorsal plaques (10.4%) and 32 ventral plaques (33.3%). There were 41 and 16 symptomatic and non-symptomatic central cerebral artery unstable plaques (P < 0.01); stable plaques and unstable plaque locations (ventral 10 vs. 22, dorsal 2 vs. 8, superior 5 vs. 11, inferior side 22 vs. 16, all P < 0.05); symptomatic side and non-symptomatic middle cerebral artery plaque location (ventral 16 vs. 16, dorsal 6 vs. 4, superior 9 vs. 7, inferior 14 vs. 24, all P < 0.05).   Conclusion  The middle cerebral artery plaques in young and middle-aged patients with acute ischemic cerebrovascular disease are mainly distributed in the lower and ventral side of the blood vessels, and the properties of symptomatic plaques are mostly unstable plaques, which tend to be distributed in the ventral, dorsal and upper side of the middle cerebral artery.

     

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