Volume 20 Issue 2
Feb.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(2): 246-250
DAI Li-li, TANG Wei, XIE Dao-yu, WU Hong-lin, CHEN Chao-hui. Construction and analysis of predictive model of poor olfactory improvement in patients with chronic rhinosinusitis after endoscopic surgery[J]. Chinese Journal of General Practice, 2022, 20(2): 246-250. doi: 10.16766/j.cnki.issn.1674-4152.002324
Citation: DAI Li-li, TANG Wei, XIE Dao-yu, WU Hong-lin, CHEN Chao-hui. Construction and analysis of predictive model of poor olfactory improvement in patients with chronic rhinosinusitis after endoscopic surgery[J]. Chinese Journal of General Practice, 2022, 20(2): 246-250. doi: 10.16766/j.cnki.issn.1674-4152.002324
shu

Construction and analysis of predictive model of poor olfactory improvement in patients with chronic rhinosinusitis after endoscopic surgery

doi: 10.16766/j.cnki.issn.1674-4152.002324

  • Department of Otorhinolaryngology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310015, China

Funds:

 2021KY896

  • Received Date: 2021-05-13
    Available Online: 2022-03-04
    Abstract
  •   Objective  To provide guidance for clinical work by constructing a predictive model of poor olfactory improvement in patients with chronic rhinosinusitis (CRS) after nasal endoscopic treatment.  Methods  The clinical data of 125 patients with CRS who underwent endoscopic sinus surgery in the Department of Otorhinolaryngology, Affiliated Hospital of Hangzhou Normal University from March 2018 to March 2021 were retrospectively analysed. All patients were accompanied by olfactory disorders. The improvement of olfactory disorders was divided into satisfactory group and unsatisfactory group. Factors affecting olfactory improvement were screened through single-factor analysis, and logistics multi-factor analysis was carried out. A prediction model was constructed according to the logistics regression equation, and its prediction performance was analysed.  Results  The clinical data of 125 patients, including 84 cases in the satisfactory group and 41 cases in the unsatisfactory group, were analysed. Logistics multivariate analysis revealed that a history of allergic diseases (B=1.145, OR=3.141, 95% CI: 1.282-7.693), nasal polyps (B=0.905, OR=2.472, 95% CI: 1.025-5.962) and long-term reduction congestion (B=1.043, OR=2.837, 95% CI: 1.164-6.917) is a risk factor for olfactory recovery. Adherence to comprehensive treatment (B= -1.225, OR=0.294, 95% CI: 0.107-0.807) is a risk factor for olfactory recovery. The nomogram model predicted that the C-index of CRS patients with poor olfactory improvement after nasal endoscopic treatment was 0.745(0.739-0.819). The calibration curve showed that the absolute error of the prediction probability of the nomogram model was 0.043.  Conclusion  A history of allergic diseases, nasal polyps, long-term decongestants and post-operative adherence to comprehensive treatment are the factors affecting olfactory recovery. The nomogram model established based on the above indicators can be used for olfactory improvement after nasal endoscopic treatment in patients with CRS patients.

     

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