Volume 20 Issue 3
Mar.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(3): 399-402
ZHANG Bing-tai, ZHANG Lei, LIU Jun, LI Hong-lin, LIU Xue-gang. Clinical effect observation of thoracoscopic lobectomy and segmentectomy in the treatment of early non-small cell lung cancer[J]. Chinese Journal of General Practice, 2022, 20(3): 399-402. doi: 10.16766/j.cnki.issn.1674-4152.002362
Citation: ZHANG Bing-tai, ZHANG Lei, LIU Jun, LI Hong-lin, LIU Xue-gang. Clinical effect observation of thoracoscopic lobectomy and segmentectomy in the treatment of early non-small cell lung cancer[J]. Chinese Journal of General Practice, 2022, 20(3): 399-402. doi: 10.16766/j.cnki.issn.1674-4152.002362
shu

Clinical effect observation of thoracoscopic lobectomy and segmentectomy in the treatment of early non-small cell lung cancer

doi: 10.16766/j.cnki.issn.1674-4152.002362
  • 1.

    Department of Thoracic and Cardiac Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2019A0340

  • Received Date: 2021-06-07
    Available Online: 2022-08-13
    Abstract
  •   Objective  To observe the clinical efficacy of thoracoscopic lobectomy and segmental lung resection in the treatment of patients with early stage non-small cell lung cancer (NSCLC), and analyse the differences between the two groups.  Methods  Sixty patients with early NSCLC who were admitted to the Department of Cardiac Surgery of the First Affiliated Hospital of Bengbu Medical College from January 2018 to December 2019 were selected. According to surgical methods, they were divided into the observation group (thoracoscopic segmentectomy) (n=30) and control group (thoracoscopic lobectomy) (n=30). Perioperative related indicators and postoperative complications were compared between the two groups, and preoperative and postoperative lung function and quality of life were analysed.  Results  Compared with the control group, the observation group had longer operation time[(140.32±12.31) min vs. (109.82±14.52) min], shorter postoperative drainage time and hospitalisation time[(5.12±1.07) days vs. (5.89±0.95) days, (7.89±1.24) days vs. (9.18±1.32) days], and lesser intraoperative blood loss[(65.09±15.45) mL vs. (86.46±17.87) mL, all P < 0.05]. The incidence of pulmonary air leakage was higher in the observation group, and no statistical significance was observed in the incidence of postoperative complications between the two groups (P>0.05). No significant difference was observed in preoperative lung function indexes (FEV1, FVC) between the two groups (all P>0.05). Statistically significant differences were observed in lung function indexes between the two groups and within the two groups at different time points after operation (all P < 0.05). An interaction was observed between group and time (Finteraction=65.982, 61.374, all P < 0.05). No significant difference was observed in preoperative KPS scores between the two groups (P>0.05). Statistically significant differences were observed in the KPS scores between the two groups and at different time points within the group after surgery (all P < 0.05). An interaction was observed between group and time (Finteraction=50.233, P < 0.05).  Conclusion  The overall effect of thoracoscopic pulmonary segmentectomy in the treatment of patients with early NSCLC is better than that of lobectomy, with lesser intraoperative bleeding, faster postoperative recovery and little impact on lung function, which has important clinical application value.

     

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