Volume 20 Issue 3
Mar.  2022
Turn off MathJax
Article Contents
ZHAO Feng, SUN Fang, WEI Guang-you, HE Hong-liang. Infection characteristics of 11 juvenile cases of COVID-19 in BoZhou City, Anhui Province[J]. Chinese Journal of General Practice, 2022, 20(3): 428-430. doi: 10.16766/j.cnki.issn.1674-4152.002369
Citation: ZHAO Feng, SUN Fang, WEI Guang-you, HE Hong-liang. Infection characteristics of 11 juvenile cases of COVID-19 in BoZhou City, Anhui Province[J]. Chinese Journal of General Practice, 2022, 20(3): 428-430. doi: 10.16766/j.cnki.issn.1674-4152.002369

Infection characteristics of 11 juvenile cases of COVID-19 in BoZhou City, Anhui Province

doi: 10.16766/j.cnki.issn.1674-4152.002369
Funds:

 2020M670084ZX

  • Received Date: 2021-04-12
    Available Online: 2022-08-13
  •   Objective  To study the epidemiological and clinical characteristics of juvenile patients with coronavirus disease 2019 (COVID-19) in BoZhou City, Anhui Province.  Methods  We conducted a retrospective study focusing on 11 juvenile patients diagnosed with COVID-19 in BoZhou City, Anhui Province from 24 January 2020 to 12 February 2020. Epidemiological, demographic, clinical, laboratory, radiological and treatment data were collected and analysed.  Results  Amongst the hospitalised juvenile patients with COVID-19, the median age was 10.54(7.5, 13.0) years, and 6(54.5%) were male. All 11 patients were detected by real-time RT-PCR, and at least 1 family members were infected with COVID-19. Patients had clinical manifestations of fever [4(36.3)% patients], mild upper respiratory tract symptoms [8(72.7%) patients], cough [2(18.2%) patients], muscle ache [1(9.1%) patients], sore throat [2(18.2%) patients] and nasal congestion [4(36.4%) patients]. One patient (9.1%) showed significant gastrointestinal symptoms and other clinical manifestations 1-2 days before the diagnosis of COVID-19. Eight patients (72.7%) had decreased lymphocyte counts, 9(81.8%) had elevated c-reactive protein levels, 3(27.2%) had elevated ALT and AST, and 4(36.4%) had normal white blood cell counts. According to imaging examination, 3(27.2%) patients showed bilateral pneumonia, and 5(45.5%) patients showed multiple mottling and ground-glass opacity.  Conclusion  Compared with adults, there are not many cases of juvenile patients, and relevant studies are insufficient. The above information provides valuable guidance for the effective management and accurate treatment of this disease.

     

  • loading
  • [1]
    中华预防医学会新型冠状病毒肺炎防控专家组. 新型冠状病毒肺炎流行病学特征的最新认识[J]. 中国病毒病杂志, 2020, 10(2): 86-92. https://www.cnki.com.cn/Article/CJFDTOTAL-ZRYX202002002.htm

    Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. An update on the epidemiological characteristics of novel coronavirus pneumonia(COVID-19)[J]. Chinese Journal of Viral Diseases, 2020, 10(2): 86-92. https://www.cnki.com.cn/Article/CJFDTOTAL-ZRYX202002002.htm
    [2]
    WANG D W, HU B, HU C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China[J]. JAMA, 2020, 323(11): 1061-1069. doi: 10.1001/jama.2020.1585
    [3]
    CHANG D, LIN M G, WEI L, et al. Epidemiologic and clinical characteristics of novel coronavirus infections involving 13 patients outside Wuhan, China[J]. JAMA, 2020, 323(11): 1092-1093. doi: 10.1001/jama.2020.1623
    [4]
    缪莎, 罗稀, 王左, 等. 重症病区新型冠状病毒肺炎患者心理状况及影响因素分析[J]. 徐州医科大学学报, 2020, 40(8): 612-616. doi: 10.3969/j.issn.2096-3882.2020.08.015

    MIAO S, LUO X, WANG Z, et al. Analysis of psychological status and influencing factors of COVID-19 patients in the intensive care unit[J]. Journal of Xuzhou Medical University, 2020, 40(8): 612-616. doi: 10.3969/j.issn.2096-3882.2020.08.015
    [5]
    蔡洁皓, 王相诗, 葛艳玲, 等. 上海首例儿童新型冠状病毒感染[J]. 中华儿科杂志, 2020, 58(2): 86-87. doi: 10.3760/cma.j.issn.0578-1310.2020.02.002

    CAI J H, WANG X S, GE Y L, et al. First case of 2019 novel coronavirus infection in children in Shanghai[J]. Chinese Journal of Pediatrics, 2020, 58(2): 86-87. doi: 10.3760/cma.j.issn.0578-1310.2020.02.002
    [6]
    国家卫生健康委办公厅国家中医药管理局办公室. 关于印发新型冠状病毒肺炎诊疗方案(试行第六版)的通知[EB/OL]. (2020-02-18)[2020-09-11]. http://bgs.satcm.gov.cn/zhengcewenjian/2020-02-19/13221.html.

    General Office of the National Health Commission and office of the State Administration of Traditional Chinese Medicine. Notice on the diagnosis and treatment of new coronavirus pneumonia (trial version sixth)[EB/OL]. (2020-02-18)[2020-09-11]. http://bgs.satcm.gov.cn/zhengcewenjian/2020-02-19/13221.html.
    [7]
    牛永亮, 时靖峰, 腾小宝, 等. 100例新型冠状病毒感染者临床病例分析[J]. 川北医学院学报, 2020, 35(3): 547-550. doi: 10.3969/j.issn.1005-3697.2020.03.049

    NIU Y L, SHI J F, TENG X B, et al. Analysis on clinical characteristics of 100 patients with novel coronavirus[J]. Journal of North Sichuan Medical College, 2020, 35(3): 547-550. doi: 10.3969/j.issn.1005-3697.2020.03.049
    [8]
    冯凯, 云永兴, 王险峰, 等. 儿童2019新型冠状病毒感染15例CT影像特征分析[J]. 中华儿科杂志, 2020, 58(4): 275-278. doi: 10.3760/cma.j.cn112140-20200210-00071

    FENG K, YUN Y X, WANG X F, et al. Analysis of CT features of 15 children with 2019 novel coronavirus infection[J]. Chinese Journal of Pediatrics, 2020, 58(4): 275-278. doi: 10.3760/cma.j.cn112140-20200210-00071
    [9]
    杨斌斌, 朱月玲. 儿童与成人新型冠状病毒肺炎的流行病学与治疗现状分析[J]. 西安交通大学学报(医学版), 2020, 41(4): 483-487. https://www.cnki.com.cn/Article/CJFDTOTAL-XAYX202004003.htm

    YANG B B, ZHU Y L. Epidemiology and treatment of novel coronavirus pneumonia in children and adults[J]. Journal of Xi ' an Jiaotong University(Medical Sciences), 2020, 41(4): 483-487. https://www.cnki.com.cn/Article/CJFDTOTAL-XAYX202004003.htm
    [10]
    PEERI N C, SHRESTHA N, RAHMAN M S, et al. The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: What lessons have we learned?[J]. Int J Epidemiol, 2020, 49(3): 717-726. doi: 10.1093/ije/dyaa033
    [11]
    DEL RIO C, MALANI P N. 2019 novel coronavirus: Important information for clinicians[J]. JAMA, 2020, 323(11): 1039-1040. doi: 10.1001/jama.2020.1490
    [12]
    KUMAR V, TAN K P, WANG Y M, et al. Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors[J]. Bioorg Med Chem, 2016, 24(13): 3035-3042. doi: 10.1016/j.bmc.2016.05.013
    [13]
    陈苗, 张旺生, 江光煚, 等. 襄阳市1 175例新型冠状病毒肺炎确诊病例流行病学特征分析[J]. 公共卫生与预防医学, 2020, 31(6): 15-18. doi: 10.3969/j.issn.1006-2483.2020.06.004

    CHEN M, ZHANG W S, JIANG G G, et al. Epidemiological characteristics of 1 175 confirmed cases of COVID-19 in Xiangyang[J]. Journal of Public Health and Preventive Medicine, 2020, 31(6): 15-18. doi: 10.3969/j.issn.1006-2483.2020.06.004
    [14]
    王巧凤, 杨艳霞, 李阳, 等. 玉溪14例新型冠状病毒肺炎患者的回顾性分析[J]. 云南医药, 2020, 41(6): 529-533. https://www.cnki.com.cn/Article/CJFDTOTAL-YNYY202006002.htm
    [15]
    ABDIRIZAK F, LEWIS R, CHOWELL G. Evaluating the potential impact of targeted vaccination strategies against severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks in the healthcare setting[J]. Theor Biol Med Mode, 2019, 16(1): 16. doi: 10.1186/s12976-019-0112-6
    [16]
    YOON S H, LEE K H, KIM J Y, et al. Chest radiographic and CT Findings of the 2019 novel coronavirus disease (COVID-19): Analysis of nine patients treated in Korea[J]. Korean J Radiol, 2020, 21(4): 494-500. doi: 10.3348/kjr.2020.0132
    [17]
    RYU S, CHUN B C. An interim review of the epidemiological characteristics of 2019 novel coronavirus[J]. Epidemiol Health, 2020, 42: e2020006. doi: 10.4178/epih.e2020006
    [18]
    任洪伟, 安维民, 董景辉, 等. 新型冠状病毒肺炎临床表现与影像学特征分析[J]. 中国临床医学, 2020, 27(3): 369-372. https://www.cnki.com.cn/Article/CJFDTOTAL-LCYX202003007.htm

    REN H W, AN W M, DONG J H, et al. Clinical and CT imaging features of COVID-19[J]. Chinese Journal of Clinical Medicine, 2020, 27(3): 369-372. https://www.cnki.com.cn/Article/CJFDTOTAL-LCYX202003007.htm
    [19]
    方峰, 罗小平. 面对2019新型冠状病毒感染重大疫情: 儿科医生的思考[J]. 中华儿科杂志, 2020, 58(2): 81-85. doi: 10.3760/cma.j.issn.0578-1310.2020.02.001

    FANG F, LUO X P. Facing the pandemic of 2019 novel coronavirus infections: the pediatric perspectives[J]. Chinese Journal of Pediatrics, 2020, 58(2): 81-85. doi: 10.3760/cma.j.issn.0578-1310.2020.02.001
    [20]
    刘苗, 万曦, 涂晓燕, 等. 一起家庭聚集性儿童感染新型冠状病毒分析[J]. 武汉大学学报(医学版), 2020, 41(3): 362-365. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYK202003005.htm

    LIU M, WAN X, TU X Y, et al. Family cluster of child SARS-CoV-2 infections: A case report[J]. Medical Journal of Wuhan University, 2020, 41(3): 362-365. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYK202003005.htm
    [21]
    钟霞, 李伟, 郭德莹, 等. COVID-19流行期间非定点收治三级综合医院感染防控实践的探索[J]. 中华全科医学, 2020, 18(12): 2117-2119, 2148. doi: 10.16766/j.cnki.issn.1674-4152.001702

    ZHONG X, LI W, GUO D Y, et al. Practice of infection prevention and control in non-designated three grade general hospital during COVID-19 epidemic period[J]. Chinese Journal of General Practice, 2020, 18(12): 2117-2119, 2148. doi: 10.16766/j.cnki.issn.1674-4152.001702
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(1)

    Article Metrics

    Article views (182) PDF downloads(1) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return