Volume 20 Issue 3
Mar.  2022
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(3): 458-460
LIU Xue, YANG Chong-yi, YANG Feng-qiang, GAO Yin, HU Zeng-gang, LI Guang-yin. Clinical effect of colour Doppler ultrasonography combined with contrast-enhanced ultrasound in the differential diagnosis of renal parenchymal tumour[J]. Chinese Journal of General Practice, 2022, 20(3): 458-460. doi: 10.16766/j.cnki.issn.1674-4152.002377
Citation: LIU Xue, YANG Chong-yi, YANG Feng-qiang, GAO Yin, HU Zeng-gang, LI Guang-yin. Clinical effect of colour Doppler ultrasonography combined with contrast-enhanced ultrasound in the differential diagnosis of renal parenchymal tumour[J]. Chinese Journal of General Practice, 2022, 20(3): 458-460. doi: 10.16766/j.cnki.issn.1674-4152.002377
shu

Clinical effect of colour Doppler ultrasonography combined with contrast-enhanced ultrasound in the differential diagnosis of renal parenchymal tumour

doi: 10.16766/j.cnki.issn.1674-4152.002377
  • 1.

    Department of Special Examination, the First Hospital of Ninghai County, Ningbo, Zhejiang 315600, China

Funds:

 2019RC272

  • Received Date: 2021-11-02
    Available Online: 2022-08-13
    Abstract
  •   Objective  To observe the clinical effect of colour Doppler ultrasonography (CDUS) and contrast-enhanced ultrasound (CEUS) in qualitative differential diagnosis of renal parenchymal tumour.  Methods  A total of 126 patients with renal parenchymal tumours in our hospital from January 2017 to August 2021 were selected as the research objects. All cases underwent CDUS and CEUS examination to analyse renal tumours with different properties. The histopathological test results were used as the gold standard to statistically analyse the difference in the diagnostic efficacy of the two detection methods in the differential diagnosis of renal tumours with different pathological types and different lesion sizes.  Results  In terms of CDUS imaging signal characteristics, malignant renal parenchymal tumours mostly protruded outside the renal contour, and most of them had pseudocapsule. Conversely, benign renal parenchymal tumours mostly did not protrude outside the renal contour, and most of them did not have a pseudocapsule. In terms of CEUS signal characteristics, malignant renal tumours were mainly characterised by fast perfusion, high intensity, uneven enhancement of the lesion and annular enhancement around the lesion, whereas benign renal tumours were mainly characterised by synchronous or slow perfusion, medium and low intensity, uniform enhancement of the lesion and no annular enhancement around the lesion. The sensitivity (91.67%), specificity (87.04%) and accuracy (89.68%) of CEUS were significantly higher than those of CDUS (72.22%, 68.52% and 70.63%; χ2=9.199, P=0.002; χ2=5.357, P=0.021; χ2=14.371, P < 0.001). The Kappa value and area under ROC curve of CEUS for the qualitative diagnosis of small renal tumour (0.789 and 0.894) were higher than those of CDUS (0.405 and 0.704).  Conclusion  CEUS is superior to CDUS in the qualitative differential diagnosis of small renal tumours. The combined application of CEUS and CDUS can improve the diagnostic efficiency of renal parenchymal tumours and is worthy of clinical application.

     

    • FullText(HTML)
  • loading
    • References(15)
  • [1]
    王旭东, 杨培谦. 肾小细胞癌的临床诊治进展[J]. 国际外科学杂志, 2018, 45(5): 352-356. doi: 10.3760/cma.j.issn.1673-4203.2018.05.016

    WANG X D, YANG P Q. Advances in clinical diagnosis and treatment of small cell carcinoma of the kidney[J]. International Journal of Surgery, 2018, 45(5): 352-356. doi: 10.3760/cma.j.issn.1673-4203.2018.05.016
    [2]
    李聪聪, 石士奎. 肾癌功能影像诊断研究进展[J]. 中国现代医药杂志, 2020, 22(1): 100-104. doi: 10.3969/j.issn.1672-9463.2020.01.031

    LI C C, SHI S K. Advances in functional imaging diagnosis of renal cell carcinoma[J]. Modern Medicine Journal of China, 2020, 22(1): 100-104. doi: 10.3969/j.issn.1672-9463.2020.01.031
    [3]
    赵广宁, 李黎明. 肾细胞癌临床治疗的新进展[J]. 医学综述, 2021, 27(8): 1545-1550. doi: 10.3969/j.issn.1006-2084.2021.08.016

    ZHAO G N, LI L M. New progress in clinical treatment of renal cell carcinoma[J]. Medical Recapitulate, 2021, 27(8): 1545-1550. doi: 10.3969/j.issn.1006-2084.2021.08.016
    [4]
    许慧莹, 李月红. 实体肿瘤相关性肾病[J]. 临床内科杂志, 2020, 37(3): 148-150. doi: 10.3969/j.issn.1001-9057.2020.03.002

    XU H Y, LI Y H. Solid tumor associated nephropathy[J]. Journal of Clinical Internal Medicine, 2020, 37(3): 148-150. doi: 10.3969/j.issn.1001-9057.2020.03.002
    [5]
    史凌波, 李军. 动态增强磁共振成像与16层螺旋CT对小肾癌诊断及术前评估的价值对比[J]. 影像科学与光化学, 2021, 39(2): 310-314. https://www.cnki.com.cn/Article/CJFDTOTAL-GKGH202102026.htm

    SHI L D, LI J. Comparison the diagnosis and preoperative evaluation of dynamic enhanced magnetic resonance imaging and 16-slice spiral CT in small renal carcinoma[J]. Imaging Science and Photochemistry, 2021, 39(2): 310-314. https://www.cnki.com.cn/Article/CJFDTOTAL-GKGH202102026.htm
    [6]
    姚治情, 陈兴发. B超引导下经皮肾穿刺活检术在肾肿瘤诊断中的应用研究[J]. 临床医学研究与实践, 2017, 2(6): 75-76. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS201706038.htm

    YAO Z Q, CHEN X F. Ultrasound guided percutaneous renal biopsy in the diagnosis of renal tumor research[J]. Clinical Research and Practice, 2017, 2(6): 75-76. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS201706038.htm
    [7]
    刘雪, 高银, 杨崇一, 等. 超声造影与增强CT对肾脏占位性病变良恶性鉴别诊断的效能比较[J]. 中华全科医学, 2020, 18(11): 1911-1915. doi: 10.16766/j.cnki.issn.1674-4152.001652

    LIU X, GAO Y, YANG C Y, et al. Comparison of the effectiveness of differential diagnosis on renal space occupying lesions between and contrast-enhanced ultrasonography and contrast-enhanced CT[J]. Chinese Journal of General Practice, 2020, 18(11): 1911-1915. doi: 10.16766/j.cnki.issn.1674-4152.001652
    [8]
    李展展. 多层螺旋CT薄层后处理技术诊断肾肿瘤的价值分析[J]. 实用医学影像杂志, 2020, 21(5): 508-511. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXY202005025.htm

    LI Z Z. The value of multi-slice spiral thin-slice CT postprocessing technique in the diagnosis of renal tumor[J]. Journal of Practical Medical Imaging, 2020, 21(5): 508-511. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXY202005025.htm
    [9]
    何小红, 纪久雨. MRI及CT对不同亚型肾细胞癌的特征分析[J]. 国际泌尿系统杂志, 2021, 41(4): 685-690. doi: 10.3760/cma.j.cn431460-20200318-00030

    HE X H, JI J Y. Characteristic analysis of different subtypes of renal cell carcinoma diagnosed by MRI and CT[J]. International Journal of Urology and Nephrology, 2021, 41(4): 685-690. doi: 10.3760/cma.j.cn431460-20200318-00030
    [10]
    余薇, 杨阳, 邬颖华. 肾癌的多模态MRI研究进展[J]. 磁共振成像, 2021, 12(9): 113-115, 120. https://www.cnki.com.cn/Article/CJFDTOTAL-CGZC202109029.htm

    YU W, YANG Y, WU Y H. Research progress of multimodal MRI in renal cell carcinoma[J]. Chinese Journal of Magnetic Resonance Imaging, 2021, 12(9): 113-115, 120. https://www.cnki.com.cn/Article/CJFDTOTAL-CGZC202109029.htm
    [11]
    朱婷, 张秋琴, 车欣, 等. 超声造影定性及定量技术在鉴别肾脏良恶性肿瘤中的应用[J]. 中国临床研究, 2020, 33(12): 1691-1693, 1697. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCK202012025.htm

    ZHU T, ZHANG Q Q, CHE X, et al. Qualitative and quantitative techniques of contrast-enhanced ultrasound in differentiating benign and malignant renal tumors[J]. Chinese Journal of Clinical Research, 2020, 33(12): 1691-1693, 1697. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCK202012025.htm
    [12]
    刘阳, 陈双喜, 朱丽, 等. 超声造影对肾脏实性肿瘤的诊断价值[J]. 中国临床保健杂志, 2021, 24(3): 394-397. doi: 10.3969/J.issn.1672-6790.2021.03.025

    LIU Y, CHEN S X, ZHU L, et al. Value of contrast-enhanced ultrasound in the diagnosis of solid renal tumor[J]. Chinese Journal of Clinical Healthcare, 2021, 24(3): 394-397. doi: 10.3969/J.issn.1672-6790.2021.03.025
    [13]
    陈淑群. 彩色多普勒超声检查对小肾癌患者的诊断价值分析[J]. 中国现代药物应用, 2020, 14(8): 38-39. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWYY202008017.htm

    CHEN S Q. Analysis of the diagnostic value of color Doppler ultrasound in small renal carcinoma[J]. Chinese Journal of Modern Drug Application, 2020, 14(8): 38-39. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWYY202008017.htm
    [14]
    汪朝阳, 黄鹏飞, 张晴, 等. 常规超声结合超声造影诊断肾占位性病变的价值[J]. 东南国防医药, 2021, 23(5): 479-483. doi: 10.3969/j.issn.1672-271X.2021.05.007

    WANG C Y, HUANG P F, ZHANG Q, et al. The value of conventional ultrasound combined with contrast-enhanced ultrasound in the diagnosis of renal space occupying lesions[J]. Military Medical Journal of Southeast China, 2021, 23(5): 479-483. doi: 10.3969/j.issn.1672-271X.2021.05.007
    [15]
    郑丽丽, 任新平, 詹维伟, 等. 常规超声结合超声造影对肾透明细胞癌与肾血管平滑肌脂肪瘤的鉴别诊断价值[J]. 第二军医大学学报, 2021, 42(6): 609-616. https://www.cnki.com.cn/Article/CJFDTOTAL-DEJD202106004.htm

    ZHANG L L, REN X P, ZHAN W W, et al. Conventional ultrasound combined with contrast-enhanced ultrasound in differential diagnosis of clear cell renal cell carcinoma and renal angiomyolipoma[J]. Academic Journal of Second Military Medical University, 2021, 42(6): 609-616. https://www.cnki.com.cn/Article/CJFDTOTAL-DEJD202106004.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (371) PDF downloads(3) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return