Volume 20 Issue 3
Mar.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(3): 511-513
WU Xiao-li, NI Jue-min, CHEN Jian-e, WANG Jian, KONG Xiang-dong. Analysis of the incidence and risk factors of cerebral infarction on maintenance haemodialysis patients[J]. Chinese Journal of General Practice, 2022, 20(3): 511-513. doi: 10.16766/j.cnki.issn.1674-4152.002389
Citation: WU Xiao-li, NI Jue-min, CHEN Jian-e, WANG Jian, KONG Xiang-dong. Analysis of the incidence and risk factors of cerebral infarction on maintenance haemodialysis patients[J]. Chinese Journal of General Practice, 2022, 20(3): 511-513. doi: 10.16766/j.cnki.issn.1674-4152.002389
shu

Analysis of the incidence and risk factors of cerebral infarction on maintenance haemodialysis patients

doi: 10.16766/j.cnki.issn.1674-4152.002389
  • 1.

    Department of Neurology, the First People's Hospital of Fuyang District, Hangzhou, Zhejiang 311400, China

Funds:

 2020KY802

  • Received Date: 2021-04-16
    Available Online: 2022-08-13
    Abstract
  •   Objective  To understand the incidence of cerebral infarction in maintenance haemodialysis (MHD) patients and analyze its influencing factors.  Methods  Total 208 uremic patients treated with MHD in the Blood Purification Center of the First People's Hospital of Fuyang District, Hangzhou from January 2018 to January 2020 were selected as the research objects. Patients were divided into the ischemic cerebral infarction group (n=23) and non-cerebral infarction group (n=185) according to whether cerebral infarction occurred during treatment. General clinical data were compared between the two groups, and risk factors for ischemic cerebral infarction in MHD patients were analysed.  Results  The incidence of ischemic cerebral infarction was 11.06% in 23 of 208 patients. Comparing the clinical indexes of the two groups of patients, the results showed that ischemic cerebral infarction patients in diabetes, coronary heart disease, atrial fibrillation, systolic pressure, diastolic blood pressure before dialysis before dialysis, uric acid were significantly higher than that of the patients in non-cerebral infarction group (all P < 0.05), and two groups of patients in the frequency of sex, age, duration of dialysis, dialysis, hyperlipidaemia, smoking history, glomerular filtration rate, oral aspirin, oral statin drugs, blood phosphorus, haemoglobin and albumin were not statistically significant (P > 0.05). Logistic regression analysis showed that coronary heart disease, diabetes mellitus, pre-dialysis systolic blood pressure, pre-dialysis diastolic blood pressure, atrial fibrillation and UA were independent risk factors for cerebral infarction in MHD patients.  Conclusion  The proportion of MHD patients with ischemic cerebral infarction is relatively high, amongst which coronary heart disease, diabetes, pre-dialysis systolic blood pressure, pre-dialysis diastolic blood pressure, atrial fibrillation and UA are independent risk factors for the occurrence of ischemic cerebral infarction in MHD patients, and corresponding prevention and treatment measures should be given in the treatment of MHD patients to reduce the risk of cerebral infarction.

     

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